CAS 106128-89-6

succinyl(asp6

Description:

Succinyl(asp6), with the CAS number 106128-89-6, is a derivative of aspartic acid, specifically modified by the addition of a succinyl group. This compound is characterized by its role as a peptide or amino acid derivative, often utilized in biochemical research and pharmaceutical applications. The succinyl group enhances the solubility and stability of the molecule, which can influence its biological activity. Succinyl(asp6) may exhibit properties such as being a zwitterion, possessing both positive and negative charges at physiological pH, which can affect its interaction with proteins and enzymes. Additionally, it may play a role in metabolic pathways or serve as a building block in peptide synthesis. The compound's structure typically includes a backbone of carbon, hydrogen, oxygen, and nitrogen atoms, contributing to its functional properties. As with many amino acid derivatives, its behavior in solution, reactivity, and potential applications can vary based on environmental conditions such as pH and temperature.

Formula: C₄₀H₅₅N₇O₁₁S

InChI: InChI=1/C40H55N7O11S/c1-24(2)19-28(37(55)45-27(36(41)54)17-18-59-4)44-33(49)23-42-39(57)31(21-26-13-9-6-10-14-26)47(3)40(58)30(20-25-11-7-5-8-12-25)46-38(56)29(22-35(52)53)43-32(48)15-16-34(50)51/h5-14,24,27-31H,15-23H2,1-4H3,(H2,41,54)(H,42,57)(H,43,48)(H,44,49)(H,45,55)(H,46,56)(H,50,51)(H,52,53)/t27-,28-,29-,30-,31-/m0/s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](CCSC)C(=N)O)O)N=C(CN=C([C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)N=C([C@H](CC(=O)O)N=C(CCC(=O)O)O)O)O)O

Synonyms:

• Succinyl-(Asp6,N-Me-Phe8)-Substance P (6-11)
• Suc-Asp-Phe-N-Me-Phe-Gly-Leu-Met-NH2
• Senktide
• N-(3-carboxypropanoyl)-L-alpha-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide
• Senktide?, BR
• Substance p (6-11), succinyl-Asp(6)-me-Phe(8)-
• L-Methioninamide, N-(3-carboxy-1-oxopropyl)-L-alpha-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-
• [SUCCINYL-ASP6 N-ME-PHE8]-SUBSTANCE P (6-11) (SENKTIDE)
• N-(3-Carboxy-1-oxopropyl)-6-(N-methyl-L-phenylalanine)-7-de-L-valine-4-10-neuromedin B (swine spinal cord)
• SUBSTANCE P SUCCINYL-[ASP6, N-ME-PHE8]-FRAGMENT 6-11
• SELECTIVE NEUROKININ B RECEPTOR PEPTIDE
• SENKTIDE (6-11)
• succinyl(asp6
• Substance P, fragment 6-11, succinyl[Asp6, NMePhe8]
• Substance p (6-11), succinyl-aspartyl(6)-methylphenylalanine(8)-
• Suc-[Asp6,MePhe8]substance P(6-11)
• DFFGLM (Modifications: Asp-1 = Succinyl-Asp, Phe-3 = Me-Phe, Met-6 = C-terminal amide) trifluoroacetate salt
• 4-10-Neuromedin B (swine spinal cord), N-(3-carboxy-1-oxopropyl)-6-(N-methyl-L-phenylalanine)-7-de-L-valine-
• L-Methioninamide, N-(3-carboxy-1-oxopropyl)-L-α-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-
• Senktide trifluoroacetate salt
• SUCCINYL-ASP-PHE-N-METHYL-PHE-GLY-LEU-MET-NH2
• N-(3-Carboxy-1-oxopropyl)-L-Asp-L-Phe-N-methyl-L-Phe-Gly-L-Leu-L-Met-NH2
• N-(3-Carboxy-1-oxopropyl)-L-αAsp-L-Phe-N-methyl-L-Phe-Gly-L-Leu-L-Met-NH2
• Succinyl-6-Asp-8-me-Phe-substance p (6-11)
• SUC-DF(ME)FGLM-NH2
• SUC-DF-(NMEF)-GLM-NH2
• [SUCCINYL-ASP6,N-ME-PHE8]-SUBSTANCE P, FRAGMENT 6-11
• SUC-[ASP6, N-ME-PHE8]-SUBSTANCE P (6-11)
• SUCCINYL-ASP-PHE-(N-ME)PHE-GLY-LEU-MET-NH2
• SUCCINYL-ASP-PHE-ME-PHE-GLY-LEU-MET-NH2
• [SUCCINYL-ASP6,ME-PHE8] SUBSTANCE P
• Suc-Asp-Phe-MePhe-Gly-Leu-Met-NH2 trifluoroacetate salt

Succinyl-(Asp⁶,N-Me-Phe⁸)-Substance P (6-11)

CAS: 106128-89-6

Senktide (selective neurokinin B receptor peptide) is a specific agonist for the substance P N-receptor in guinea pig ileum.

Formula: C₄₀H₅₅N₇O₁₁S

Purity: 99.0%

Molecular weight: 841.98

Ref: 01-4012515

Senktide

CAS: 106128-89-6

Formula: C₄₀H₅₅N₇O₁₁S

Purity: %

Color and Shape: Solid

Molecular weight: 841.9700

Ref: IN-DA00845A

Senktide

CAS: 106128-89-6

Senktide

Purity: ≥98%

Molecular weight: 841.97g/mol

Ref: 54-BUP21982

Senktide

CAS: 106128-89-6

Senktide is an agonist of tachykinin NK3 receptor.

Formula: C₄₀H₅₅N₇O₁₁S

Purity: 99.84% - >99.99%

Color and Shape: White Powder

Molecular weight: 841.97

Ref: TM-T7633

Senktide

CAS: 106128-89-6

Purity: 98%

Molecular weight: 841.98

Ref: 10-F979601

Succinyl-(Asp6,N-Me-Phe8)-Substance P (6-11)

CAS: 106128-89-6

Succinyl-(Asp6,N-Me-Phe8)-Substance P (6-11) Suc-Asp-Phe-N-Me-Phe-Gly-Leu-Met-NH2 is a synthetic opioid peptide that binds to the κ receptor. It has been shown to have analgesic effects in animal models of chronic pain and inflammatory pain. The peptide has also been shown to have antiinflammatory activity in a rat model of adjuvant arthritis. Succinyl-(Asp6,N-Me-Phe8)-Substance P (6-11) Suc-Asp-Phe can be used as a pharmacological agent for the treatment of autoimmune diseases such as multiple sclerosis. It may also be used as a treatment for brain disorders related to memory or learning. Succinyl-(Asp6,N-Me--Phe8)-Substance P (6--11) Suc--

Formula: C₄₀H₅₅N₇O₁₁S

Purity: Min. 95%

Molecular weight: 841.97 g/mol

Ref: 3D-FS109556