CAS 109358-47-6

N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide

Description:

N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide, with CAS number 109358-47-6, is a synthetic compound characterized by its complex structure, which includes multiple amino acid residues and a benzopyran moiety. This compound features a dimethylethoxycarbonyl protecting group, which is commonly used in peptide synthesis to protect the amino group of the amino acids. The presence of L-leucine, L-lysine, and L-arginine indicates that it is a peptide derivative, potentially exhibiting biological activity. The benzopyran component suggests potential pharmacological properties, as compounds in this class are often associated with antioxidant and anti-inflammatory effects. The overall molecular structure implies that it may interact with biological systems, possibly influencing protein synthesis or enzyme activity. Its solubility, stability, and reactivity would depend on the specific conditions, such as pH and solvent, making it a candidate for further research in medicinal chemistry and drug development.

Formula: C₃₃H₅₂N₈O₇

InChI: InChI=1S/C33H52N8O7/c1-19(2)16-25(41-32(46)48-33(4,5)6)30(45)40-23(10-7-8-14-34)29(44)39-24(11-9-15-37-31(35)36)28(43)38-21-12-13-22-20(3)17-27(42)47-26(22)18-21/h12-13,17-19,23-25H,7-11,14-16,34H2,1-6H3,(H,38,43)(H,39,44)(H,40,45)(H,41,46)(H4,35,36,37)/t23-,24-,25-/m0/s1

InChI key: InChIKey=RRHPIUJOSIJECH-SDHOMARFSA-N

SMILES: CC=1C=2C(=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC(OC(C)(C)C)=O)CC(C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)=CC2)OC(=O)C1

Synonyms:

• <span class="text-smallcaps">L</smallcap>-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
• Boc-Leu-Lys-Arg-AMC
• Boc-Leu-Lys-Arg-Amc Hydrochloride Salt
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</smallcap>-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-<smallcap>L</span>-argininamide
• L-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
• N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide

Boc-Leu-Lys-Arg-AMC

CAS: 109358-47-6

Boc-LKR-AMC, a good substrate for the Kex2 endoprotease (kexin, previously known as proteinase yscF), a membrane-bound, calcium-dependent serine protease from yeast α-cells.

Formula: C₃₃H₅₂N₈O₇

Purity: 98.4%

Color and Shape: White Crystalline Powder

Molecular weight: 672.83

Ref: 01-4017091

Boc-Leu-Lys-Arg-AMC

CAS: 109358-47-6

Boc-Leu-Lys-Arg-AMC is an inhibitor of the human erythrocyte receptor for thrombin. It has shown activity in a number of other protein interactions, such as with the human receptor for epidermal growth factor (EGF) and the human receptor for insulin-like growth factor II. Boc-Leu-Lys-Arg-AMC is used as a research tool to study the function of proteins, including ion channels and receptors. This compound is also used as an antibody in immunological studies that examine protein interactions. Boc-Leu-Lys-Arg-AMC can be purchased in high purity and at a reasonable price from our store.

Formula: C₃₃H₅₂N₈O₇

Purity: Min. 95%

Molecular weight: 672.82 g/mol

Ref: 3D-MLK-3141-V

Boc-Leu-Lys-Arg-AMC hydrochloride salt

CAS: 109358-47-6

Boc-Leu-Lys-Arg-AMC is a synthetic substrate that has been used in a number of clinical studies to identify the serine proteases that are involved in autoimmune diseases. It is a synthetic peptide composed of the amino acid sequence found in soybean trypsin. The peptide was shown to have high salt tolerance and was able to be hydrolyzed by polyclonal antibodies with specificity for amyloid protein, suggesting it may be useful as a biochemical marker for Alzheimer's disease. Boc-Leu-Lys-Arg-AMC has also been shown to be an efficient substrate for collagenase, which is an enzyme that breaks down collagen and causes tissue damage. This property makes this compound useful as a proteolytic agent for the removal of unwanted scar tissue or other lesions from diseased organs. Boc-Leu-Lys-Arg-AMC also has an optimum pH level of 7.5 and is active against influenza

Formula: C₃₃H₅₂N₈O₇

Purity: Min. 95%

Molecular weight: 672.82 g/mol

Ref: 3D-FB110554