CAS 113866-14-1: BOC-GRR-AMC

Description: BOC-GRR-AMC, with the CAS number 113866-14-1, is a chemical compound that serves as a substrate in biochemical assays, particularly in the study of proteases. It is characterized by the presence of a BOC (tert-butyloxycarbonyl) protecting group, which is commonly used in peptide synthesis to protect amino groups. The GRR sequence indicates the presence of specific amino acids, likely arginine and glycine, which can be relevant for enzyme specificity. The AMC (7-amino-4-methylcoumarin) moiety is a fluorogenic group that emits fluorescence upon cleavage, making it useful for monitoring enzymatic activity in real-time. This compound is typically utilized in research settings to investigate proteolytic activity and enzyme kinetics. Its stability, solubility in organic solvents, and the ability to provide a measurable fluorescent signal upon reaction make it a valuable tool in biochemical and pharmaceutical research. Proper handling and storage conditions are essential to maintain its integrity and reactivity.

Formula: C₂₉H₄₄N₁₀O₇

Synonyms:

• T-Butyloxycarbonylglycyl-L-Arginyl-L-Arginine 4-Methylcoumaryl-7-Amide
• Boc-Gly-Arg-Arg-Mca
• Boc-Gly-Arg-Arg-Amc
• tert-butyl N-[2-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]carbamate
• BOC-GRR-AMC
• L-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]glycyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
• TERT-BUTYLOXYCARBONYL-GLYCYL-L-ARGINYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE

Boc-Gly-Arg-Arg-AMC

CAS: 113866-14-1

A substrate for flavivirus proteases such as West Nile virus protease, yellow fever virus NS3 …

• Formula: C₂₉H₄₄N₁₀O₇
• Purity: 98.7%
• Color and Shape: White Powder
• Molecular weight: 644.73

Boc-Gly-Arg-Arg-AMC acetate salt

CAS: 113866-14-1

Boc-Gly-Arg-Arg-AMC acetate salt is a protease inhibitor that inhibits the activity of serine proteases. This …

• Formula: C₂₉H₄₄N₁₀O₇•(C₂H₄O₂)x
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 644.72 g/mol

Boc-Gly-Arg-Arg-AMC

CAS: 113866-14-1

Boc-Gly-Arg-Arg-AMC is a research tool that has a high purity and is used in cell …

• Formula: C₂₉H₄₄N₁₀O₇
• Purity: Min. 95%
• Molecular weight: 644.72 g/mol

Boc-Gly-Arg-Arg-AMC trifluoroacetate

CAS: 113866-14-1

Boc-Gly-Arg-Arg-AMC trifluoroacetate is a potent inhibitor of kinases, which are enzymes that play a crucial …

• Formula: C₂₉H₄₄N₁₀O₇•(C₂HF₃O₂)x
• Purity: Min. 95%
• Color and Shape: Powder