CAS 116853-25-9: Cefluprenam

Description: Cefluprenam is a synthetic antibiotic belonging to the cephalosporin class, characterized by its broad-spectrum activity against various bacterial pathogens. It is primarily used in the treatment of infections caused by Gram-positive and Gram-negative bacteria. The compound features a beta-lactam ring, which is essential for its antibacterial action, as it inhibits bacterial cell wall synthesis. Cefluprenam is known for its stability against certain beta-lactamases, enzymes produced by bacteria that can inactivate many antibiotics. This stability enhances its efficacy against resistant strains. The substance is typically administered via injection and is metabolized in the liver, with its excretion primarily occurring through the kidneys. Its pharmacokinetic profile allows for effective tissue penetration, making it suitable for treating systemic infections. As with other antibiotics, potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in normal flora. Overall, cefluprenam represents a valuable option in the arsenal against bacterial infections, particularly in cases where resistance to other antibiotics is a concern.

Formula: C₂₀H₂₅FN₈O₆S₂

InChI: InChI=1S/C20H25FN8O6S2/c1-3-29(2,7-11(22)30)6-4-5-10-8-36-18-13(17(32)28(18)14(10)19(33)34)24-16(31)12(26-35-9-21)15-25-20(23)37-27-15/h4-5,13,18H,3,6-9H2,1-2H3,(H5-,22,23,24,25,27,30,31,33,34)/b5-4+,26-12-/t13-,18-,29?/m1/s1

InChI key: InChIKey=XAKKNLNAJBNLPC-MAYKBZFQSA-N

SMILES: O=C([O-])C1=C(C=CC[N+](C)(CC(=O)N)CC)CSC2N1C(=O)C2NC(=O)C(=NOCF)C3=NSC(=N3)N

Synonyms:

• (-)-((E)-3-((6R,7R)-7-(2-(5-Amino-1,2,4-thiadiazol-3-yl)glyoxylamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo (4.2.0)oct-2-en-3-yl)allyl)(carbamoylmethyl)ethylmethylammonium hydroxide, inner salt, 7(sup 2)-(Z)-(O-(fluoromethyl)oxime)
• (-)-[(E)-3-[(6R,7R)-7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)glyoxylamido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]allyl](carbamoylmethyl)ethylmethylammonium hydroxide, inner salt, 7²-(Z)-[O-(fluoromethyl)oxime]
• 1,2,4-Thiadiazole, 2-propen-1-aminium deriv.
• 2-Propen-1-aminium, N-(2-amino-2-oxoethyl)-3-(7-(((5-amino-1,2,4-thiadiazol-3-yl)((fluoromethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)-N-ethyl-N-methyl-, inner salt, (6R-(3(E),6-alpha,7-beta(Z)))-
• 2-Propen-1-aminium, N-(2-amino-2-oxoethyl)-3-[(6R,7R)-7-[[(2Z)-(5-amino-1,2,4-thiadiazol-3-yl)[(fluoromethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]-N-ethyl-N-methyl-, inner salt, (2E)-
• 2-Propen-1-aminium, N-(2-amino-2-oxoethyl)-3-[(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(fluoromethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]-N-ethyl-N-methyl-, inner salt, (2E)-
• 2-Propen-1-aminium, N-(2-amino-2-oxoethyl)-3-[7-[[(5-amino-1,2,4-thiadiazol-3-yl)[(fluoromethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]-N-ethyl-N-methyl-, inner salt, [6R-[3(E),6α,7β(Z)]]-
• Antibiotic E 1077
• Cefluprenam [INN]
• E 1077
• Unii-098633Q42P

Cefluprenam

CAS: 116853-25-9

Cefluprenam is a a cephalosporin type antibacterial agent.

• Formula: C₂₀H₂₅FN₈O₆S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 556.59

Cefluprenam

CAS: 116853-25-9

• Formula: C₂₀H₂₅FN₈O₆S₂
• Color and Shape: Neat
• Molecular weight: 556.591

Cefluprenam

CAS: 116853-25-9

Cefluprenam is a broad-spectrum antibiotic that inhibits the growth of bacteria and fungi by binding …

• Formula: C₂₀H₂₅FN₈O₆S₂
• Purity: Min. 95%
• Molecular weight: 556.60 g/mol