CAS 118-57-0

Acetaminosalol

Description:

Acetaminosalol, also known as acetaminophen salicylate, is a chemical compound that combines the analgesic and antipyretic properties of acetaminophen with the anti-inflammatory effects of salicylate. It is characterized by its ability to relieve pain and reduce fever, making it useful in various therapeutic applications. The compound typically appears as a white to off-white crystalline powder and is soluble in water, which facilitates its use in pharmaceutical formulations. Acetaminosalol is often utilized in the treatment of mild to moderate pain and is considered to have a lower risk of gastrointestinal side effects compared to traditional non-steroidal anti-inflammatory drugs (NSAIDs). However, it is essential to monitor dosages carefully, as excessive intake can lead to hepatotoxicity, particularly due to the acetaminophen component. The compound's CAS number, 118-57-0, is a unique identifier that aids in its classification and regulatory oversight in chemical databases. Overall, acetaminosalol serves as a valuable option in pain management, balancing efficacy with a relatively favorable safety profile.

Formula: C₁₅H₁₃NO₄

InChI: InChI=1/C15H13NO4/c1-10(17)16-11-6-8-12(9-7-11)20-15(19)13-4-2-3-5-14(13)18/h2-9,18H,1H3,(H,16,17)

InChI key: InChIKey=TWIIVLKQFJBFPW-UHFFFAOYSA-N

SMILES: C(OC1=CC=C(NC(C)=O)C=C1)(=O)C2=C(O)C=CC=C2

Synonyms:

• 2-Hydroxybenzoic acid 4-(acetylamino)phenyl ester
• 4-(Acetylamino)Phenyl 2-Hydroxybenzoate
• 4-Acetamidophenyl Salicylate
• 4′-Hydroxyacetanilide salicylate
• Asalphen
• Benzoic acid, 2-hydroxy-, 4-(acetylamino)phenyl ester
• Cetosal
• Cetosalol
• Phenestal
• Phenetsal
• Phenosol
• Salicylic acid, ester with 4′-hydroxyacetanilide
• Salicylic acid, p-acetamidophenyl ester
• Salofena
• Salophen
• p-Acetamidophenyl salicylate
• p-Acetylaminophenyl salicylate
• 2-hydroxybenzoic acid (4-acetamidophenyl) ester
• acetaminosalol
• ACETYL-P-AMINOPHENYLSALICYLATE
• Salicylic acid 4-(acetylamino)phenyl
• (4-acetamidophenyl) 2-hydroxybenzoate
• 4-Acetaminophenyl salicylate

Acetaminosalol

CAS: 118-57-0

Color and Shape: Neat

Ref: 61-FOR1609.00

Acetaminosalol

CAS: 118-57-0

Formula: C₁₅H₁₃NO₄

Color and Shape: White

Molecular weight: 271.27

Ref: 86-MM1609.00

Acetaminosalol

Controlled Product

CAS: 118-57-0

Applications Acetaminosalol is used in cosmetic use; found in sunscreen. Also, is antipyretic agent treatment of VR1-antagonist-induced body temperature increase.
References Oliphant, T., et al.: U.S. Pat. Appl. Publ., (2011); Bannon, A., et al.: PCT Int. Appl.,(2006);

Formula: C₁₅H₁₃NO₄

Color and Shape: White

Molecular weight: 271.27

Ref: TR-A118570