Propargyl-PEG9-alcohol is a chemical compound characterized by its structure, which includes a propargyl group and a polyethylene glycol (PEG) moiety with nine ethylene glycol units, terminated by a hydroxyl group. This compound is typically used in bioconjugation and drug delivery applications due to its hydrophilic PEG segment, which enhances solubility and biocompatibility. The propargyl group allows for click chemistry reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating the attachment of various biomolecules or drugs. The presence of the hydroxyl group provides additional reactivity and can serve as a site for further functionalization. Propargyl-PEG9-alcohol is generally stable under standard laboratory conditions but should be handled with care, as with all chemical substances, to avoid any potential hazards. Its unique combination of hydrophilicity and reactive functional groups makes it a valuable tool in the fields of medicinal chemistry and materials science.

Propargyl-PEG9-alcohol is a crosslinker that can participate in copper catalyzed azide-alkyne Click Chemistry reactions to form stable triazole linkage. The PEG spacer increases the hydrophilicity of the molecule in aqueous media.

Propargyl-PEG9-alcohol

1351556-81-4: Propargyl-PEG9-alcohol is a chemical compound characterized by its structure, which includes a propargyl group and a polyethylene glycol (PEG) moiety with nine ethylene glycol units, terminated by a hydroxyl group. This compound is typically used in bioconjugation and drug delivery applications due to its hydrophilic PEG segment, which enhances solubility and biocompatibility. The propargyl group allows for click chemistry reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating the attachment of various biomolecules or drugs. The presence of the hydroxyl group provides additional reactivity and can serve as a site for further functionalization. Propargyl-PEG9-alcohol is generally stable under standard laboratory conditions but should be handled with care, as with all chemical substances, to avoid any potential hazards. Its unique combination of hydrophilicity and reactive functional groups makes it a valuable tool in the fields of medicinal chemistry and materials science.

<p>Propargyl-PEG8-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

CAS 1351556-81-4

Propargyl-PEG9-alcohol

Propargyl-PEG9-alcohol

Ref: 54-BIPG1718

Propargyl-PEG8-OH

Ref: TM-T16652

Propargyl-PEG8-OH

Ref: 10-F570399