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CAS 142955-50-8

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boc-glycine N-carboxy anhydride

Description:
Boc-glycine N-carboxy anhydride (Boc-Gly-NCA) is a cyclic imide derivative of glycine, characterized by its unique structure that includes a tert-butyloxycarbonyl (Boc) protecting group and an N-carboxy anhydride functionality. This compound is typically used in peptide synthesis, particularly in the preparation of poly(amino acids) through ring-opening polymerization. Boc-Gly-NCA is known for its stability under dry conditions and can be sensitive to moisture, which may lead to hydrolysis. It is generally soluble in organic solvents such as dichloromethane and dimethylformamide, making it suitable for various organic synthesis applications. The presence of the Boc group provides a protective mechanism for the amino group, allowing for selective reactions. Additionally, Boc-Gly-NCA can facilitate the formation of peptide bonds, making it a valuable intermediate in the synthesis of peptides and proteins. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested, and appropriate personal protective equipment should be used.
Formula:C8H11NO5
Synonyms:
  • tert-Butyl 2,5-dioxooxazolidine-3-carboxylate
  • N-Boc-glycine N-Carboxyanhydride
  • BOC-GLYCINE NCA
  • 2,5-Dioxo-3-oxazolidinecarboxylic Acid 1,1-DiMethylethyl Ester
  • 3-Oxazolidinecarboxylic acid, 2,5-dioxo-, 1,1-dimethylethyl ester
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Found 2 products.
  • N-Boc-glycine N-carboxyanhydride
    Biosynth
    + Info

    N-Boc-glycine N-carboxyanhydride

    CAS:
    N-Boc-glycine N-carboxyanhydride is a reagent that is used to prepare the activated ester of pyridine with an alkyl ester. It is soluble in a variety of solvents and has a high reactivity. This product can be used in peptide synthesis, especially for the protection of alpha amino groups during coupling reactions. It has been shown to have good fluorine atom properties, as well as an electronegativity that is higher than that of chlorine or bromine.
    Formula:C8H11NO5
    Purity:Min. 98 Area-%
    Color and Shape:Powder
    Molecular weight:201.18 g/mol

    Ref: 3D-FB18946

    1g
    513.00€
    2g
    883.00€
    5g
    1,513.00€
    10g
    2,678.00€
    500mg
    349.00€
  • N-Boc-glycine N-Carboxyanhydride
    TRC
    + Info

    N-Boc-glycine N-Carboxyanhydride

    Controlled Product
    CAS:

    Applications Used in the preparation of polyesters with functional-peptide blocks.
    References Pierschbacher, M., et al.: Nature, 309, 30 (1984), Kowalski, A., et al.: Macromolecules, 33, 1964 (2000), Kubies, D., et al.: Biomaterials, 21, 529 (2000),

    Formula:C8H11NO5
    Color and Shape:Neat
    Molecular weight:201.177

    Ref: TR-B656130

    10g
    1,509.00€