CymitQuimica logo

CAS 148179-94-6

:

spongistatin 1

Description:
Spongistatin 1 is a natural product derived from marine organisms, specifically from the sponge *Spongia officinalis*. It is classified as a polyketide and exhibits a complex molecular structure characterized by multiple rings and functional groups. Spongistatin 1 has garnered attention in the field of medicinal chemistry due to its potent biological activities, particularly its ability to inhibit cell proliferation and induce apoptosis in various cancer cell lines. This compound interacts with cellular pathways, making it a subject of interest for cancer research and drug development. Additionally, spongistatin 1 has shown potential in modulating immune responses, which could have implications for treating autoimmune diseases. Its unique structure and biological properties make it a valuable compound for further investigation in pharmacology and therapeutic applications. However, due to its complex nature, the synthesis and extraction of spongistatin 1 can be challenging, necessitating advanced techniques in organic chemistry and biochemistry for its study and potential application.
Formula:C63H95ClO21
InChI:InChI=1/C63H95ClO21/c1-33(19-43(67)18-17-35(3)64)20-53-55(72)58-80-54(71)26-46-24-48(77-40(8)65)30-62(83-46)32-60(10,74)28-49(84-62)21-34(2)36(4)56(78-41(9)66)38(6)50(69)25-45-23-47(76-11)29-61(82-45)27-44(68)22-42(39(61)7)15-13-12-14-16-52-37(5)51(70)31-63(75,85-52)57(73)59(79-53)81-58/h13,15,17-18,36-39,42-49,51-53,55-59,67-68,70,72-75H,1-3,12,14,16,19-32H2,4-11H3/b15-13u,18-17+
Synonyms:
  • 8,12,45,46,47,48,50-Heptaoxaheptacyclo(39.3.1.1(1,5).1(9,13).1(15,19).1(25,29).1(29,33))pentacont-23-ene-7,35-dione, 3,37-bis(acetyloxy)-11-(7-chloro-4-hydroxy-2-methylene-5,7-octadienyl)-10,14,15,17,27,43-hexahydroxy-31-methoxy-18,36,38,43,49-pentamethyl-39-methylene-
  • 8,12,45,46,47,48,50-Heptaoxaheptacyclo(39.3.1.11,5.19,13.115,19.125,29.129,33)pentacont-23-ene-7,35-dione, 3,37-bis(acetyloxy)-11-(7-chloro-4-hydroxy-2-methylene-5,7-octadienyl)-10,14,15,17,27,43-hexahydroxy-31-methoxy-18,36,38,43,49-pentamethyl-39-methyl
  • 11-[(5E)-7-chloro-4-hydroxy-2-methylideneocta-5,7-dien-1-yl]-10,14,15,17,27,43-hexahydroxy-31-methoxy-18,36,38,43,47-pentamethyl-39-methylidene-7,35-dioxo-8,12,45,46,48,49,50-heptaoxaheptacyclo[39.3.1.11,5.19,13.115,19.125,29.129,33]pentacont-23-ene-3,37-diyl diacetate
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 1 products.
  • Spongistatin 1
    Biosynth
    + Info

    Spongistatin 1

    CAS:
    <p>Spongistatin 1 is a complex macrocyclic lactone, which is a potent cytotoxic compound originally isolated from marine sponges. This compound is derived from sponges of the genus Spongia, primarily found in the Indo-Pacific region. Spongistatin 1 exerts its effects through the disruption of microtubule dynamics, thereby inhibiting mitosis in tumor cells. It binds to tubulin, preventing microtubule assembly, which is crucial for cellular division, leading to cell cycle arrest and apoptosis in cancer cells.</p>
    Formula:C63H95ClO21
    Purity:Min. 95%
    Molecular weight:1,223.87 g/mol

    Ref: 3D-XS177353

    ne
    To inquire