CAS 148498-78-6

adrenomedullin 52 human

Description:

Adrenomedullin 52 is a peptide that plays a significant role in various physiological processes, including vasodilation, regulation of blood pressure, and modulation of inflammatory responses. It is derived from the adrenomedullin precursor protein and consists of 52 amino acids. This peptide is primarily produced in the adrenal medulla and has been found in various tissues throughout the body, indicating its widespread biological relevance. Adrenomedullin 52 functions by binding to specific receptors, leading to the activation of signaling pathways that promote smooth muscle relaxation and enhance blood flow. Additionally, it has been implicated in the pathophysiology of several conditions, including cardiovascular diseases and metabolic disorders. The CAS number 148498-78-6 uniquely identifies this substance in chemical databases, facilitating research and regulatory processes. Its stability, solubility, and biological activity make it a subject of interest in pharmacological studies, particularly in the development of therapeutic agents targeting cardiovascular and inflammatory diseases.

Formula: C₂₆₄H₄₀₆N₈₀O₇₇S₃

Synonyms:

• Adrenomedullin
• Human adrenomedullin
• Adrenomedullin (human)
• H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bond)

Adrenomedullin (1-52), Human

CAS: 148498-78-6

For cellular and molecular biology applications

Color and Shape: White, Lyophilized Powder

Ref: 02-J66379

Adrenomedullin (human)

CAS: 148498-78-6

Adrenomedullin (ADM) elicits a potent and longlasting hypotensive effect and is considered as a hormone involved in blood pressure control. Additionally, ADM acts as a protective factor of blood vessels. Adrenomedullin is a potent stimulator of osteoblastic activity. Further biological activities of hADM include reduction of oxidative stress and inhibition of endothelial cell apoptosis.

Formula: C₂₆₄H₄₀₆N₈₀O₇₇S₃

Purity: ≥ 97%

Color and Shape: White

Molecular weight: 6028.82

Ref: 01-4030315

ADRENOMEDULLIN (HUMAN)

CAS: 148498-78-6

Formula: C₂₆₄H₄₀₆N₈₀O₇₇S₃

Purity: 95%

Molecular weight: 6028.7332

Ref: IN-DA001KY6

Adrenomedullin (AM) (1-52), human

CAS: 148498-78-6

Adrenomedullin (AM) (1-52), human is a 52-amino acid peptide that modulates cellular proliferation and angiogenesis in cancer.

Formula: C₂₆₄H₄₀₆N₈₀O₇₇S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 6028.82

Ref: TM-TP1146

Adrenomedullin (human)

CAS: 148498-78-6

Adrenomedullin (human)

Ref: 54-BIBA1020

Adrenomedullin (Human)

CAS: 148498-78-6

Adrenomedullin (human) is a research tool that has been shown to activate the ligand receptor. It is a member of the vasoactive peptide family, which includes adrenalin and noradrenaline. Adrenomedullin binds to the cell surface receptors on smooth muscle cells and endothelial cells and activates ion channels. This research tool is also known as AM.

Formula: C₂₆₄H₄₀₆N₈₀O₇₇S₃

Purity: Min. 95%

Molecular weight: 6,028.7 g/mol

Ref: 3D-PAD-4278-S

Adrenomedullin (human) trifluoroacetate salt

CAS: 148498-78-6

Adrenomedullin is a human peptide hormone that is produced and secreted by the heart in response to stress. It has been shown to play a role in the regulation of blood pressure, cardiac function, and inflammation. Adrenomedullin has been shown to increase blood flow to the kidneys and lungs, which may be due to its ability to induce pulmonary vasodilation. Adrenomedullin also plays a role in ischemic preconditioning by inducing cardioprotection through guanine nucleotide-binding proteins. The effects of low doses of adrenomedullin on cardiovascular parameters have been studied in humans.

Formula: C₂₆₄H₄₀₆N₈₀O₇₇S₃

Purity: Min. 95%

Molecular weight: 6,028.74 g/mol

Ref: 3D-FA108807