CAS: 152044-53-6 - (-)-EPOTHILONE A

Formula: C₂₆H₃₉NO₆S

InChI: InChI=1S/C26H39NO6S/c1-14-8-7-9-19-21(32-19)11-20(15(2)10-18-13-34-17(4)27-18)33-23(29)12-22(28)26(5,6)25(31)16(3)24(14)30/h10,13-14,16,19-22,24,28,30H,7-9,11-12H2,1-6H3/b15-10+/t14-,16+,19+,20-,21-,22-,24-/m0/s1

InChI key: InChIKey=HESCAJZNRMSMJG-KKQRBIROSA-N

SMILES: O=C1OC(C(=CC=2N=C(SC2)C)C)CC3OC3CCCC(C)C(O)C(C(=O)C(C)(C)C(O)C1)C

Synonyms:

• (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
• (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
• 4,17-Dioxabicyclo14.1.0heptadecane-5,9-dione, 7,11-dihydroxy-8,8,10,12-tetramethyl-3-(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl-, (1S,3S,7S,10R,11S,12S,16R)-
• 4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-, (1S,3S,7S,10R,11S,12S,16R)-
• 4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-8,8,10,12-tetramethyl-3-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-, [1R*,3R*(E),7R*,10S*,11R*,12R*,16S*]-
• Epo A

Epothilone A

CAS: 152044-53-6

• Formula: C₂₆H₃₉NO₆S
• Purity: ≥98%
• Color and Shape: Solid
• Molecular weight: 493.6560

Ixabepilone Impurity 5 (Epothilone A)

CAS: 152044-53-6

• Formula: C₂₆H₃₉NO₆S
• Color and Shape: Off-White Solid
• Molecular weight: 493.67

(-)-Epothilone A

CAS: 152044-53-6

• Formula: C₂₆H₃₉NO₆S
• Molecular weight: 493.66

Epothilone A

CAS: 152044-53-6

Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.

• Formula: C₂₆H₃₉NO₆S
• Purity: 99.48%
• Color and Shape: Solid
• Molecular weight: 493.66

Epothilone A

CAS: 152044-53-6

Applications The epothilones are a novel class of antineoplastic agents possessing antitubulin activity. Epothilone A, …

• Formula: C₂₆H₃₉NO₆S
• Color and Shape: White to Off-White Solid
• Molecular weight: 493.66

Epothilone A

CAS: 152044-53-6

Epothilone A is an anti-cancer drug that inhibits the mcl-1 protein, which is a member …

• Formula: C₂₆H₃₉NO₆S
• Purity: Min. 95%
• Molecular weight: 493.66 g/mol