5(6)-Carboxynaphthofluorescein diacetate is a fluorescent dye commonly used in biological and chemical research, particularly in cell imaging and tracking applications. This compound is a derivative of fluorescein, characterized by its carboxyl and diacetate functional groups, which enhance its solubility and fluorescence properties. The presence of the carboxyl group allows for potential conjugation with biomolecules, making it useful for labeling and detection purposes. The diacetate moiety serves as a protective group that can be hydrolyzed in the presence of esterases, releasing the active fluorescent form of the dye. This property is particularly advantageous for live-cell imaging, as it minimizes background fluorescence until the dye is activated within the cell. The compound exhibits strong absorption and emission in the visible spectrum, making it suitable for various fluorescence microscopy techniques. Overall, 5(6)-carboxynaphthofluorescein diacetate is valued for its versatility, stability, and effectiveness in visualizing cellular processes.

5(6)-carboxynaphthofluorescein diacetate

163831-68-3: 5(6)-Carboxynaphthofluorescein diacetate is a fluorescent dye commonly used in biological and chemical research, particularly in cell imaging and tracking applications. This compound is a derivative of fluorescein, characterized by its carboxyl and diacetate functional groups, which enhance its solubility and fluorescence properties. The presence of the carboxyl group allows for potential conjugation with biomolecules, making it useful for labeling and detection purposes. The diacetate moiety serves as a protective group that can be hydrolyzed in the presence of esterases, releasing the active fluorescent form of the dye. This property is particularly advantageous for live-cell imaging, as it minimizes background fluorescence until the dye is activated within the cell. The compound exhibits strong absorption and emission in the visible spectrum, making it suitable for various fluorescence microscopy techniques. Overall, 5(6)-carboxynaphthofluorescein diacetate is valued for its versatility, stability, and effectiveness in visualizing cellular processes.

<p>Applications 3,11-bis(Acetyloxy)carboxynaphthofluorescein is an intermediate in the synthesis of 5-(6)-Carboxynaphthofluoroscein N-Succinimidyl Ester (C179025), a derivative compound of 5(6)-Carboxyfluorescein (C178315), which functions as a useful reagent for the preparation of hydrolytically stable fluorescent conjugates and is a useful starting material for the synthesis of other fluorescein-derives reagent.<br>References Theisen, P., et al.: Tetrahedron Lett., 33, 5033 (1992), Mattingly, P.: Bioconjgate Chem., 3, 430 (1992, Bertrand, R., et al.: Biochemistry, 34, 9500 (1995)<br></p>

CAS 163831-68-3

5(6)-carboxynaphthofluorescein diacetate

3,11-bis(Acetyloxy)carboxynaphthofluorescein

Ref: TR-A178345