CAS 16839-98-8

Noratropine

Description:

Noratropine, with the CAS number 16839-98-8, is a chemical compound that belongs to the class of tropane alkaloids. It is structurally related to atropine and scopolamine, which are well-known tropane derivatives. Noratropine is characterized by its bicyclic structure, which includes a nitrogen atom in a six-membered ring, contributing to its pharmacological properties. This compound exhibits anticholinergic activity, meaning it can inhibit the action of acetylcholine at muscarinic receptors, leading to effects such as reduced secretions and muscle relaxation. Noratropine is of interest in medicinal chemistry due to its potential applications in treating various conditions, including motion sickness and muscle spasms. However, its specific therapeutic uses and safety profile require further investigation. As with many alkaloids, the biological activity of noratropine can be influenced by its stereochemistry and the presence of functional groups, making it a subject of study in both pharmacology and organic synthesis.

Formula: C₁₆H₂₁NO₃

InChI: InChI=1/C16H21NO3/c18-10-15(11-4-2-1-3-5-11)16(19)20-14-8-12-6-7-13(9-14)17-12/h1-5,12-15,17-18H,6-10H2/t12-,13+,14+,15?

InChI key: InChIKey=ATKYNAZQGVYHIB-MCOXGKPRNA-N

SMILES: O(C(C(CO)C1=CC=CC=C1)=O)[C@H]2C[C@@]3(N[C@](C2)(CC3)[H])[H]

Synonyms:

• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Nortropan-3α-ol, (±)-tropate (ester)
• 2-[3-(8-Azabicyclo[3.2.1]Oct-3-Yl)Phenyl]-3-Hydroxypropanoic Acid
• 8-Azabicyclo[3.2.1]Oct-3-Yl 3-Hydroxy-2-Phenylpropanoate
• 8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate
• Benzeneacetic acid, alpha-(hydroxymethyl)-, (3-endo)-8-azabicyclo(3.2.1)oct-3-yl ester
• Benzeneacetic acid, alpha-(hydroxymethyl)-, 8-azabicyclo(3.2.1)oct-3-yl ester, endo-(+-)-
• Benzeneacetic acid, α-(hydroxymethyl)-, (3-endo)-8-azabicyclo[3.2.1]oct-3-yl ester
• Benzeneacetic acid, α-(hydroxymethyl)-, 8-azabicyclo[3.2.1]oct-3-yl ester, endo-
• N-Demethylatropine
• Norhyoscyamine
• 1αH,5αH-Nortropan-3α-ol, (±)-tropate (ester)

Noratropine

CAS: 16839-98-8

Formula: C₁₆H₂₁NO₃

Purity: 95%

Molecular weight: 275.3428

Ref: IN-DA001Y1B

Noratropine

CAS: 16839-98-8

Noratropine

Formula: C₁₆H₂₁NO₃

Purity: 95%

Molecular weight: 275.34

Ref: 54-OR1139308

Atropine EP Impurity B (Noratropine)

CAS: 16839-98-8

Formula: C₁₆H₂₁NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 275.35

Ref: 4Z-A-151034

Noratropine (Standard)

CAS: 16839-98-8

Noratropine (Standard) is a reference standard for research and analysis in studies involving Noratropine. Noratropine is a metabolite of Atropine (A794625).

Formula: C₁₆H₂₁NO₃

Color and Shape: Solid

Molecular weight: 275.34

Ref: TM-TMSM-2662

Noratropine

CAS: 16839-98-8

Natural alkaloid

Formula: C₁₆H₂₁NO₃

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 275.34

Ref: 5G-84107

Atropine EP Impurity B

CAS: 16839-98-8

Formula: C₁₆H₂₁NO₃

Molecular weight: 275.35

Ref: ST-EA-CP-A206002

Noratropine

CAS: 16839-98-8

Noratropine is a drug that belongs to the group of anticholinergic drugs. It is used as a pharmaceutical preparation for the treatment of urinary incontinence and other conditions that are caused by overactivity of the bladder muscles. Noratropine has been shown to have a significant effect on symptoms such as increased urination, urgency, frequency, and nocturia. In addition, it reduces the amount of urine produced at night and during the day. Noratropine can be found in pueraria lobata (Kudzu) and angelicae dahuricae (Angelica). These plants contain natural compounds with anticholinergic properties. Noratropine can also be synthesized from benzalkonium chloride and n-oxide. The synthesis involves two steps: first, benzalkonium chloride reacts with an alcohol to form an acid which then reacts with n-oxide to produce noratropine. This compound can also be obtained from tissue

Formula: C₁₆H₂₁NO₃

Purity: Min. 95%

Molecular weight: 275.34 g/mol

Ref: 3D-FN26428