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CAS 22960-18-5

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8-bromo-6-fluoroquinoline

Description:
8-Bromo-6-fluoroquinoline is a heterocyclic organic compound belonging to the quinoline family, characterized by a fused bicyclic structure containing a benzene ring and a pyridine ring. The presence of bromine and fluorine substituents at the 8 and 6 positions, respectively, significantly influences its chemical properties and reactivity. This compound typically exhibits a pale yellow to brownish appearance and is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its biological activity. The bromine atom can enhance lipophilicity and influence the compound's interaction with biological targets, while the fluorine atom can improve metabolic stability and bioavailability. 8-Bromo-6-fluoroquinoline may also exhibit fluorescence properties, making it useful in various analytical applications. Its synthesis often involves halogenation reactions and can be achieved through various methods, including electrophilic aromatic substitution. As with many halogenated compounds, it is essential to handle it with care due to potential toxicity and environmental concerns.
Formula:C9H5BrFN
InChI:InChI=1/C9H5BrFN/c10-8-5-7(11)4-6-2-1-3-12-9(6)8/h1-5H
SMILES:c1cc2cc(cc(c2nc1)Br)F
Synonyms:
  • Quinoline, 8-Bromo-6-Fluoro-
  • 8-Bromo-6-fluoroquinoline
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