CAS 231620-64-7
:3'-N-Demethylation Erythromycin A Oxime
Description:
3'-N-Demethylation Erythromycin A Oxime, identified by its CAS number 231620-64-7, is a derivative of erythromycin, a macrolide antibiotic. This compound is characterized by the modification of the erythromycin structure, specifically involving the demethylation at the 3' nitrogen position and the presence of an oxime functional group. As a result, it retains antibacterial properties, primarily effective against Gram-positive bacteria, while exhibiting a modified pharmacological profile compared to its parent compound. The oxime group can influence the compound's solubility, stability, and reactivity, potentially affecting its bioavailability and therapeutic efficacy. Additionally, this compound may be of interest in medicinal chemistry for its potential applications in antibiotic development and resistance studies. Its synthesis and characterization involve standard organic chemistry techniques, and it is typically analyzed using methods such as NMR spectroscopy and mass spectrometry to confirm its structure and purity. Overall, 3'-N-Demethylation Erythromycin A Oxime represents a significant modification of erythromycin that may enhance its clinical utility.
Formula:C36H66N2O13
Synonyms:- Erythromycin, N-demethyl-, 9-oxime, (9E)-
- 3'-N-Demethylation Erythromycin A Oxime
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