CAS 243973-20-8

Pinoxaden

Description:

Pinoxaden is a selective herbicide primarily used for controlling grass weeds in various crops, particularly in cereals. It belongs to the chemical class of aryloxyphenoxypropionic acids and functions by inhibiting the enzyme acetyl-CoA carboxylase, which is crucial for fatty acid synthesis in plants. This inhibition disrupts the growth of target weeds while minimizing harm to broadleaf crops. Pinoxaden is characterized by its relatively low toxicity to mammals and its moderate persistence in the environment, which makes it a suitable choice for integrated weed management. It is typically applied post-emergence, allowing for effective control of established grass weeds. The substance is formulated in various ways, including emulsifiable concentrates and granules, to enhance its application and effectiveness. Additionally, Pinoxaden has a favorable environmental profile, with low potential for groundwater contamination and minimal impact on non-target organisms when used according to label instructions. Its efficacy and safety make it a valuable tool in modern agricultural practices.

Formula: C₂₃H₃₂N₂O₄

InChI: InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3

InChI key: InChIKey=MGOHCFMYLBAPRN-UHFFFAOYSA-N

SMILES: O(C(C(C)(C)C)=O)C1=C(C(=O)N2N1CCOCC2)C3=C(CC)C=C(C)C=C3CC

Synonyms:

• 8-(2,6-Diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl-2,2-dimethylpropanoat
• 8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl pivalate
• 8-(2,6-diethyl-p-tolyl)-1,2,4,5-tetrahydro-7-oxo-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl
• NewAxial
• Pinoxaden
• Propanoic acid, 2,2-dimethyl-, 8-(2,6-diethyl-4-methylphenyl)-1,2,4,5-tetrahydro-7-oxo-7H-pyrazolo(1,2-d)(1,4,5)oxadiazepin-9-yl ester

Pinoxaden

CAS: 243973-20-8

Pinoxaden

Molecular weight: 400.51g/mol

Ref: 54-BIP162

Pinoxaden

Controlled Product

CAS: 243973-20-8

Formula: C₂₃H₃₂N₂O₄

Color and Shape: Neat

Molecular weight: 400.51

Ref: 04-C16215000

Pinoxaden 100 µg/mL in Acetonitrile

CAS: 243973-20-8

Formula: C₂₃H₃₂N₂O₄

Color and Shape: Single Solution

Molecular weight: 400.51

Ref: 04-A16215000AL-100

Pinoxaden

CAS: 243973-20-8

Formula: C₂₃H₃₂N₂O₄

Molecular weight: 400.52

Ref: 4Z-P-258001

Pinoxaden-d3

Controlled Product

CAS: 243973-20-8

Applications Pinoxaden-d3 is a deuterized labeled form of Pinoxaden (P469505), which is derived from Diethylene Glycol Dimethanesulfonate (D444275), an intermediate in the production of alkylating agents.
References Wong, I., et al.: J. Med. Chem., 52, 5311 (2009); Muehlebach, M., et al.: Bioorg. Med. Chem., 17, 4241 (2009)

Formula: C₂₃H₂₉D₃N₂O₄

Color and Shape: Off-White

Molecular weight: 403.53

Ref: TR-P469507

Pinoxaden

CAS: 243973-20-8

Formula: C₂₃H₃₂N₂O₄

Color and Shape: White To Beige

Molecular weight: 400.51

Ref: TR-P469505

Pinoxaden

CAS: 243973-20-8

Pinoxaden is a protein kinase inhibitor that has shown promising results in the treatment of cancer. It specifically targets cyclin-dependent kinases, which are key regulators of cell division and proliferation. By inhibiting these kinases, Pinoxaden induces apoptosis (programmed cell death) in cancer cells, thereby preventing tumor growth and metastasis. This drug is an analog of a Chinese herbal medicine and has been shown to have potent anticancer activity both in vitro and in vivo. In addition, Pinoxaden has low toxicity and is excreted primarily through urine, making it a promising candidate for further development as an anticancer agent.

Formula: C₂₃H₃₂N₂O₄

Purity: Min. 95%

Molecular weight: 400.5 g/mol

Ref: 3D-TJA97320