CAS 245329-78-6

N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]hexadecanamide

Description:

N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]hexadecanamide, with CAS number 245329-78-6, is a synthetic organic compound characterized by its complex structure, which includes a long aliphatic chain (hexadecanamide) and a bicyclic aromatic system (dihydro-benzodioxin). This compound features multiple functional groups, including hydroxyl and amide groups, contributing to its potential solubility in various solvents and biological activity. The presence of the pyrrolidine moiety suggests possible interactions with biological targets, making it of interest in medicinal chemistry. Its stereochemistry, indicated by the (1R,2R) configuration, may influence its pharmacological properties and interactions with receptors or enzymes. The compound's lipophilicity, derived from the hexadecane chain, may also affect its membrane permeability and bioavailability. Overall, this substance is likely to exhibit unique chemical and biological properties, warranting further investigation for potential applications in pharmaceuticals or related fields.

Formula: C₃₁H₅₂N₂O₄

InChI: InChI=1/C31H52N2O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-30(34)32-27(25-33-20-15-16-21-33)31(35)26-18-19-28-29(24-26)37-23-22-36-28/h18-19,24,27,31,35H,2-17,20-23,25H2,1H3,(H,32,34)/t27-,31-/m1/s1

Synonyms:

• N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(pyrrolidin-1-ylmethyl)ethyl]hexadecanamide
• D-t-EtDO-P4
• EtDO-P4
• Hexadecanamide, N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-
• N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]hexadecanamide

Hexadecanamide,N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-

CAS: 245329-78-6

Formula: C₃₁H₅₂N₂O₄

Purity: 98%

Molecular weight: 516.7556

Ref: IN-DA002OFZ

EtDO-P4

CAS: 245329-78-6

EtDO-P4 is a glucosylceramide synthase inhibitor which reduces the cellular levels of glucosylceramide (Glc-Cer) and the common biosynthetic precursor of most glycosphingolipids (GSLs). EtDO-P4 binds to the Glc-Cer synthase in a competitive manner and prevents the transfer of the first glucosyl residue, thus preventing further biosynthetic diversification into more elaborate glycosphingolipds. EtDO-P4 is a ceramide-like compound that was initially developed as a potential therapeutic for the treatment of diseases associated with altered glycosphingolipid levels. EtDO-P4 has also been used to indirectly increase sialylation levels in erythropoietin production. EtDO-P4 has been suggested, as part of compositions, for treatment of cardiac hypertrophy (Kwak, 2017).

Formula: C₃₁H₅₂N₂O₄

Purity: Min. 95%

Molecular weight: 516.76 g/mol

Ref: 3D-BE180400