CAS 24916-90-3

Dexamethasone 9,11-epoxide

Description:

Dexamethasone 9,11-epoxide is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is derived from dexamethasone, a well-known glucocorticoid, and features an epoxide functional group at the 9 and 11 positions of the steroid structure, which can influence its biological activity and metabolism. The compound is typically used in various therapeutic applications, including the treatment of inflammatory conditions, autoimmune disorders, and certain types of cancer. Its mechanism of action involves the modulation of gene expression through interaction with glucocorticoid receptors, leading to reduced inflammation and immune response. Dexamethasone 9,11-epoxide is characterized by its stability under standard conditions, but like many corticosteroids, it may undergo metabolic conversion in the body. Safety and efficacy profiles are essential considerations in its use, as corticosteroids can have significant side effects, particularly with long-term administration. As with any pharmaceutical compound, proper handling and adherence to safety guidelines are crucial in both clinical and laboratory settings.

Formula: C₂₂H₂₈O₅

InChI: InChI=1S/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)22(15)18(27-22)10-20(16,3)21(12,26)17(25)11-23/h6-7,9,12,15-16,18,23,26H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19+,20+,21+,22-/m1/s1

InChI key: InChIKey=GBDXNHBVYAMODG-QDBZYVRYSA-N

SMILES: C[C@@]12[C@@]34[C@]([C@]5([C@](C)(C[C@@]3(O4)[H])[C@](C(CO)=O)(O)[C@H](C)C5)[H])(CCC1=CC(=O)C=C2)[H]

Synonyms:

• (9B,11B,16A)-9,11-Epoxy-17,21-Dihydroxy-16-Methyl-Pregna-1,4-Diene-3,20-Dione
• (9β,11β,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
• 16-Alpha Methyl Epoxide
• 16-beta Methyl Epoxide
• 16a-MethylEpoxide
• 16α-Methyl epoxide(8-DM)
• 17,21-Dihydroxy-16-Methyl-9,11-Epoxypregna-1,4-Diene-3,20-Dione
• 8DM
• 9β-Pregna-1,4-diene-3,20-dione, 9,11β-epoxy-17,21-dihydroxy-16α-methyl-
• Dexamethasone 9,11-epoxide
• Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-16-methyl-, (9β,11β,16α)-

11β-Epoxydexamethasone (9β,11β-Epoxy-17,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione)

CAS: 24916-90-3

Ketone-phenols and ketones with other oxygen function

Formula: C₂₂H₂₈O₅

Color and Shape: White Crystalline Solid

Molecular weight: 372.19367

Ref: 45-1A06420

Pregna-1,4-diene-3,20-dione

CAS: 24916-90-3

Formula: C₂₂H₂₈O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 372.4547

Ref: IN-DA002PUT

Dexamethasone 9,11-epoxide

CAS: 24916-90-3

Dexamethasone 9,11-epoxide

Purity: ≥98%

Molecular weight: 372.45g/mol

Ref: 54-BUP11053

Dexamethasone EP Impurity D (Mometasone Furoate EP Impurity L)

CAS: 24916-90-3

Formula: C₂₂H₂₈O₅

Color and Shape: Off-White Solid

Molecular weight: 372.46

Ref: 4Z-D-3631

Dexamethasone 9,11-epoxide

CAS: 24916-90-3

Dexamethasone 9,11-epoxide

Purity: 98%

Molecular weight: 372.458g/mol

Ref: 54-OR97154

Dexamethasone EP Impurity D (Mometasone Furoate EP Impurity L)

Controlled Product

CAS: 24916-90-3

Formula: C₂₂H₂₈O₅

Color and Shape: Neat

Molecular weight: 372.45

Ref: 86-MM0213.04

Dexamethasone 9,11-epoxide

CAS: 24916-90-3

Dexamethasone 9,11-epoxide is a compound obtained by extraction and is an intermediate in the preparation of dexamethasone.

Formula: C₂₂H₂₈O₅

Purity: 98.76%

Color and Shape: Pale-Yellow Solid

Molecular weight: 372.45

Ref: TM-T19277

Dexamethasone EP Impurity D

CAS: 24916-90-3

Formula: C₂₂H₂₈O₅

Molecular weight: 372.46

Ref: ST-EA-CP-D17004

Dexamethasone 9,11-Epoxide

CAS: 24916-90-3

Impurity Mometasone Impurity L
Applications Dexamethasone intermediate.
References Isogai, M., et al.: J. Steroid Biochem. Mol. Biol., 44, 141 (1993),

Formula: C₂₂H₂₈O₅

Color and Shape: Neat

Molecular weight: 372.45

Ref: TR-D298795

Dexamethasone 9,11-Epoxide-d5

Controlled Product

CAS: 24916-90-3

Applications Dexamethasone 9,11-Epoxide-d5, is the labeled analogue of the unlabeled (D298795 ), a Dexamethasone intermediate.
References Isogai, M., et al.: J. Steroid Biochem. Mol. Biol., 44, 141 (1993),

Formula: C₂₂H₂₃D₅O₅

Color and Shape: Off-White

Molecular weight: 377.49

Ref: TR-D298797

Dexamethasone 9,11-epoxide

CAS: 24916-90-3

Please enquire for more information about Dexamethasone 9,11-epoxide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₂H₂₈O₅

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 372.45 g/mol

Ref: 3D-FD21402

Dexamethasone 9,11-Epoxide D3

Controlled Product

CAS: 24916-90-3

Formula: C₂₂D₃H₂₅O₅

Color and Shape: Neat

Molecular weight: 375.47

Ref: TR-D298796

Dexamethasone 9,11-epoxide

CAS: 24916-90-3

Purity: 98%

Molecular weight: 372.4609985

Ref: 10-F787629