CAS 2647-50-9

Flubromazepam

Description:

Flubromazepam is a chemical compound belonging to the benzodiazepine class, which is known for its psychoactive properties. It is characterized by its molecular structure, which includes a bromine atom and a benzodiazepine core, contributing to its pharmacological effects. Flubromazepam is recognized for its anxiolytic, sedative, and muscle relaxant properties, making it potentially useful in the treatment of anxiety disorders and insomnia. The compound acts primarily by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased neuronal inhibition. Its effects can vary based on dosage and individual response, and it may lead to side effects such as drowsiness, dizziness, and dependence with prolonged use. Flubromazepam is not approved for medical use in many countries and is often classified as a controlled substance due to its potential for abuse and addiction. As with other benzodiazepines, caution is advised when considering its use, particularly regarding dosage and duration of treatment.

Formula: C₁₅H₁₀BrFN₂O

InChI: InChI=1S/C15H10BrFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)

InChI key: InChIKey=ZRKDDZBVSZLOFS-UHFFFAOYSA-N

SMILES: BrC=1C=C2C(=NCC(=O)NC2=CC1)C3=C(F)C=CC=C3

Synonyms:

• 7-Bromo-5-(2-fluorophenyl)-1,3-dihydrobenzo[e]-1,4-diazepin-2-one
• Flubromazepam
• 2H-1,4-Benzodiazepin-2-one, 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-
• 7-Bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
• 2H-1,4-Benzodiazepin-2-one, 7-bromo-5-(o-fluorophenyl)-1,3-dihydro-

Flubromazepam (7-Bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one) 1.0 mg/ml in Methanol

Controlled Product

CAS: 2647-50-9

Color and Shape: Single Solution

Ref: 61-AMP1442.00-01

Flubromazepam (7-Bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one)

Controlled Product

CAS: 2647-50-9

Color and Shape: Neat

Ref: 61-FOR1442.00

Flubromazepam

Controlled Product

CAS: 2647-50-9

Applications Flubromazepam is a designer benzodiazepine drug structurally related to Phenazepam (P295300); a drug used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. Phenazepam (P295300) can also be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety.
References Moosmann, B., et al.: J. Mass Spectrom., 48, 1150 (2013); Ogiso, T., et al.: Chem. Pharm. Bull., 37, 446 (1989); Gu, Q., et al.: J. Med. Chem., 36, 1001 (1993); Bekhterev, V.N., et al.: Pharm. Chem. J., 42, 95 (2008)

Formula: C₁₅H₁₀BrFN₂O

Color and Shape: White

Molecular weight: 333.16

Ref: TR-F418600

Flubromazepam (1 mg/ml in Methanol)

Controlled Product

CAS: 2647-50-9

Formula: C₁₅H₁₀BrFN₂O

Color and Shape: Single Solution

Molecular weight: 333.16

Ref: TR-KIT2365

7-Bromo-5-(2-fluorophenyl)-1,3-dihydrobenzo[e]-1,4-diazepin-2-one

Controlled Product

CAS: 2647-50-9

7-Bromo-5-(2-fluorophenyl)-1,3-dihydrobenzo[e]-1,4-diazepin-2-one is a trifluoroacetic acid derivative that is a benzodiazepine with immunomodulatory and antimicrobial properties. It has shown to be effective against infectious diseases such as tuberculosis and malaria. The pharmacokinetics of 7-bromo-5-(2-fluorophenyl)-1,3-dihydrobenzo[e]-1,4-diazepin-2 one have been studied in human serum and the kinetic parameters are determined by using creatine kinase as the terminal enzyme. This compound has also been found to affect the matrix effect of liquid chromatography/mass spectrometry (LC/MS) for the analysis of lorazepam.

Formula: C₁₅H₁₀BrFN₂O

Purity: Min. 95%

Molecular weight: 333.16 g/mol

Ref: 3D-FB103654

2H-1,4-Benzodiazepin-2-one, 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-

CAS: 2647-50-9

Formula: C₁₅H₁₀BrFN₂O

Color and Shape: Solid

Molecular weight: 333.1551

Ref: IN-DA002TDA