CAS 33522-95-1

(-)-Noroxymorphone

Description:

(-)-Noroxymorphone is an opioid analgesic that is a derivative of oxymorphone, primarily known for its potent analgesic properties. It is classified as a semi-synthetic opioid and is structurally related to morphine, exhibiting a similar mechanism of action by binding to the mu-opioid receptors in the central nervous system. This compound is characterized by its stereochemistry, specifically the presence of a specific chiral center that contributes to its pharmacological effects. (-)-Noroxymorphone is typically encountered in research settings and is not commonly used in clinical practice due to its potential for abuse and addiction, similar to other opioids. Its pharmacokinetics involve metabolism primarily in the liver, and it may produce effects such as analgesia, sedation, and euphoria, alongside potential side effects like respiratory depression and constipation. Safety and regulatory considerations are paramount due to its classification as a controlled substance in many jurisdictions. Overall, (-)-Noroxymorphone represents a significant compound in the study of opioid pharmacology and its implications in pain management.

Formula: C₁₆H₁₇NO₄

InChI: InChI=1/C16H17NO4/c18-9-2-1-8-7-11-16(20)4-3-10(19)14-15(16,5-6-17-11)12(8)13(9)21-14/h1-2,11,14,17-18,20H,3-7H2/t11-,14+,15+,16-/m1/s1

InChI key: InChIKey=HLMSIZPQBSYUNL-IPOQPSJVSA-N

SMILES: O[C@]12[C@@]34C=5C(O[C@]3(C(=O)CC1)[H])=C(O)C=CC5C[C@]2(NCC4)[H]

Synonyms:

• (-)-Noroxymorphone
• (5Alpha)-3,14-Dihydroxy-4,5-Epoxymorphinan-6-One
• (5Beta)-3,14-Dihydroxy-4,5-Epoxymorphinan-6-One
• (5alpha)-4,5-Epoxy-3,14-dihydroxymorphinan-6-one
• 14-Hydroxydihydronormorphinone
• 7,8-Dihydro-14-hydroxynormorphinone
• En 3169
• Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-, (5α)-
• Morphinan-6-one, 4,5α-epoxy-3,14-dihydroxy-
• Normorphinone, 7,8-dihydro-14-hydroxy-
• Unii-9Nz7111A9O
• (5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-one
• Naloxone Impurity 7（Naloxone EP Impurity A）
• Naloxone HCl Impurity
• Naltrexone Impurity 6 Monomer
• Naltrexone EP Impurity B
• LTREXONE HYDROCHLORIDE - IMPURITY B
• 4,5α-Epoxy-3,14-dihydroxymorphinan-6-one
• Naltrexone hydrochloride iMpurity B
• (5a)-4,5-Epoxy-3,14-dihydroxy-morphinan-6-one
• 4-Hydroxydihydronormorphinone
• Noroxymorphone hydrochloride solution
• Methanol(test NoroxymorphoneHCl,100μg/mLasfreebase)
• (4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one
• Naloxone EP Impurity A
• Naltrexone EP Impuirty B
• Naloxone Hydrochloride Impurit Ⅰ:(5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
• NoroxyMorphone HCl
• Naloxone?Hydrochloride EP Impurity A
• Nor Oxymorphone (1.0mg/ml in DMSO)

Nor Oxymorphone

Controlled Product

CAS: 33522-95-1

Applications A metabolite of Naloxone and Naltrexone.
References Cone, E., et al.: Drug Metab. Dispos., 6, 488 (1978), Leow, K., et al.: Ther. Drug Monit., 14, 479 (1992), Kassahun, K., et al.: Drug Metab. Dispos., 25, 81 (1997),

Formula: C₁₆H₁₇NO₄

Color and Shape: Neat

Molecular weight: 287.31

Ref: TR-N825300

Naltrexone impurity B

Controlled Product

CAS: 33522-95-1

Naltrexone impurity B is an impurity standard for the chemical compound Naltrexone, which is a drug used to treat opioid addiction. It is also a high-purity material for other applications such as pharmaceutical research and development, analytical chemistry, and toxicology studies. Naltrexone impurity B has been synthesized from natural sources and can be custom-synthesized to meet customer requirements. The compound is metabolized in both animals and humans, but the metabolites have not been identified. This product has not been evaluated by the FDA for safety or efficacy.

Formula: C₁₆H₁₇NO₄

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 287.31 g/mol

Ref: 3D-IN167106

Nor Oxymorphone-d5 (major) Hydrochloride

Controlled Product

CAS: 33522-95-1

Stability Hygroscopic
Applications Nor Oxymorphone-d5 Hydrochloride labelled analogue of Nor Oxymorphone (N825300), a metabolite of Naloxone and Naltrexone.
References Cone, E., et al.: Drug Metab. Dispos., 6, 488 (1978); Leow, K., et al.: Ther. Drug Monit., 14, 479 (1992); Kassahun, K., et al.: Drug Metab. Dispos., 25, 81 (1997)

Formula: C₁₆H₁₂D₅NO₄·HCl

Color and Shape: Neat

Molecular weight: 328.8

Ref: TR-N825303

Nor Oxymorphone (1 mg/ml in DMSO)

Controlled Product

CAS: 33522-95-1

Formula: C₁₆H₁₇NO₄

Color and Shape: Single Solution

Molecular weight: 287.31

Ref: TR-KIT0025

...Noroxymorphone

CAS: 33522-95-1

Please enquire for more information about ...Noroxymorphone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₆H₁₇NO₄

Purity: Min. 95%

Molecular weight: 287.31 g/mol

Ref: 3D-FN26470

Naltrexone EP Impurity B

CAS: 33522-95-1

Formula: C₁₆H₁₇NO₄

Molecular weight: 287.3

Ref: ST-EA-CP-N57002

Naloxone EP Impurity A

CAS: 33522-95-1

Formula: C₁₆H₁₇NO₄

Molecular weight: 287.32

Ref: ST-EA-CP-N37002