CAS 34523-34-7

4′-Hydroxyacetophenone oxime

Description:

4′-Hydroxyacetophenone oxime, with the CAS number 34523-34-7, is an organic compound characterized by the presence of both a hydroxyl group and an oxime functional group. It is derived from acetophenone, where the acetyl group is substituted with a hydroxyl group at the para position and an oxime group. This compound typically appears as a solid and is known for its potential applications in organic synthesis, particularly as an intermediate in the production of various pharmaceuticals and agrochemicals. Its structure contributes to its reactivity, allowing it to participate in various chemical reactions, including condensation and oxidation. Additionally, 4′-Hydroxyacetophenone oxime may exhibit biological activity, making it of interest in medicinal chemistry. The compound is generally soluble in organic solvents, and its properties can vary based on environmental conditions such as temperature and pH. Safety data should be consulted for handling and storage, as with any chemical substance.

Formula: C₈H₉NO₂

InChI: InChI=1S/C8H9NO2/c1-6(9-11)7-2-4-8(10)5-3-7/h2-5,10-11H,1H3

InChI key: InChIKey=BVZSQTRWIYKUSF-UHFFFAOYSA-N

SMILES: C(=NO)(C)C1=CC=C(O)C=C1

Synonyms:

• Ethanone, 1-(4-hydroxyphenyl)-, oxime
• p-Hydroxyacetophenone oxime
• 1-(4-Hydroxyphenyl)ethanone oxime
• Acetophenone, 4′-hydroxy-, oxime
• 4′-Hydroxyacetophenone oxime

4'-Hydroxyacetophenone Oxime

CAS: 34523-34-7

Formula: C₈H₉NO₂

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 151.17

Ref: 3B-H1512

4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one

CAS: 34523-34-7

Formula: C₈H₉NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 151.1626

Ref: IN-DA00C9FF

4’-Hydroxyacetophenone Oxime

CAS: 34523-34-7

4’-Hydroxyacetophenone Oxime

Purity: 98%

Molecular weight: 151.16g/mol

Ref: 54-OR1011391

Paracetamol EP Impurity G

CAS: 34523-34-7

Formula: C₈H₉NO₂

Color and Shape: White To Off-White Solid

Molecular weight: 151.17

Ref: 4Z-A-0219

1-(4-Hydroxyphenyl)ethanone Oxime (4-Hydroxyacetophenone Oxime)

Controlled Product

CAS: 34523-34-7

Formula: C₈H₉NO₂

Color and Shape: Neat

Molecular weight: 151.16

Ref: 86-MM0042.12

4’-Hydroxyacetophenone Oxime

Controlled Product

CAS: 34523-34-7

Impurity Paracetamol EP Impurity G
Applications 4’-Hydroxyacetophenone Oxime is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).
References (1) Sengupta, S., et al.: Metal. Based Drugs, 8, 293 (2002) (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)

Formula: C₈H₉NO₂

Color and Shape: Neat

Molecular weight: 151.16

Ref: TR-H741050

4-Hydroxyacetophenone oxime

CAS: 34523-34-7

Molecular weight: 151.165

Ref: 10-F987074

Paracetamol EP Impurity G

CAS: 34523-34-7

Formula: C₈H₉NO₂

Molecular weight: 151.17

Ref: ST-EA-CP-P10007

4-Hydroxyacetophenone oxime

CAS: 34523-34-7

4-Hydroxyacetophenone oxime is a reactive amide that can be synthesized by the Suzuki coupling of 4-hydroxyacetophenone and an allyl bromide. This product reacts with aluminium, chloride, and hydrochloric acid to produce a nucleophilic attack. The reaction products are alkanoic acids, which are recycled for use in the next process in this synthetic process. Trifluoroacetic acid is used as a catalyst, protonating the 4-hydoxyacetophenone oxime and producing trifluoroacetic anhydride.

Formula: C₈H₉NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 151.16 g/mol

Ref: 3D-FH67568

4-Hydroxyacetophenone oxime

CAS: 34523-34-7

4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol), a potent COX-2 and hepatic NAT2 inhibitor used as an antipyretic and analgesic drug.

Formula: C₈H₉NO₂

Color and Shape: Solid

Molecular weight: 151.16

Ref: TM-T10143