CAS 36051-31-7

5′-GTP trisodium salt

Description:

5′-GTP trisodium salt, also known as trisodium guanosine-5'-triphosphate, is a nucleotide that plays a crucial role in cellular processes, particularly in signal transduction and protein synthesis. It is characterized by its structure, which includes a guanine base, a ribose sugar, and three phosphate groups, with the sodium ions providing solubility in aqueous solutions. This compound is typically a white to off-white powder and is highly soluble in water, making it useful in various biochemical applications. In biological systems, 5′-GTP acts as a substrate for RNA synthesis and is involved in the activation of G-proteins, which are essential for transmitting signals within cells. The trisodium salt form enhances its stability and solubility, facilitating its use in laboratory settings, such as in enzyme assays and molecular biology experiments. Additionally, it is important to handle this compound with care, as it can be sensitive to light and moisture, which may affect its stability and reactivity.

Formula: C₁₀H₁₆N₅O₁₄P₃·3Na

InChI: InChI=1S/C10H16N5O14P3.3Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;/t3-,5-,6-,9-;;;/m1.../s1

InChI key: InChIKey=RLEBUCJSVMPZDI-CYCLDIHTSA-N

SMILES: O[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=C(N)N3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O.[Na]

Synonyms:

• 5′-GTP trisodium salt
• Guanosine 5-triphosphate sodium salt hydrate
• Guanosine 5′-(tetrahydrogen triphosphate), trisodium salt
• Guanosine-5'-Triphosphate,Trisodium Salt
• trisodium 5'-O-(hydroxy{[(phosphonatooxy)phosphinato]oxy}phosphoryl)guanosine

Guanosine 5'-(tetrahydrogen triphosphate), trisodium salt

CAS: 36051-31-7

Formula: C₁₀H₁₆N₅NaO₁₄P₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 546.1702

Ref: IN-DA00I759

Guanosine 5’-Triphosphate Sodium Salt Hydrate

CAS: 36051-31-7

Guanosine 5’-Triphosphate Sodium Salt Hydrate

Purity: 95%

Molecular weight: 589.13g/mol

Ref: 54-OR1013446

Guanosine 5'-triphosphate trisodium salt

CAS: 36051-31-7

Guanosine 5'-triphosphate trisodium salt

Purity: ≥98%

Molecular weight: 589.13g/mol

Ref: 54-BUP15888

Guanosine 5''-triphosphate sodium salt hydrate

CAS: 36051-31-7

Formula: C₁₀H₁₆N₅O₁₄P₃·xNa

Purity: ≥ 90.0%

Color and Shape: White powder

Molecular weight: 523.18 (free acid)

Ref: 7W-GN6493

Guanosine 5'-triphosphate trisodium salt

CAS: 36051-31-7

5'-GTP trisodium salt activates G proteins, regulates cell proliferation/apoptosis, and aids DNA/RNA biosynthesis.

Formula: C₁₀H₁₃N₅Na₃O₁₄P₃

Purity: 98.74% - 99.45%

Color and Shape: White Powder

Molecular weight: 589.13

Ref: TM-T4969

Guanosine-5'-triphosphate Trisodium Salt (Technical Grade)

Controlled Product

CAS: 36051-31-7

Formula: C₁₀H₁₃N₅Na₃O₁₄P₃

Color and Shape: White To Off-White

Molecular weight: 588.94

Ref: TR-G837910

Guanosine 5'-triphosphate sodium salt hydrate

CAS: 36051-31-7

Guanosine 5'-triphosphate sodium salt hydrate (GTP) is an energy-rich nucleotide that is synthesized from guanosine and inorganic phosphate. GTP acts as a coenzyme in the synthesis of proteins, lipids, and other biological molecules. It also has been shown to inhibit the growth of murine sarcoma virus by regulating intracellular calcium levels. GTP's binding to a receptor on the surface of cells leads to a cascade of reactions that ultimately lead to the production of proteins. This process can be inhibited by pharmacological agents such as thiostrepton, which blocks GTP's incorporation into proteins.

Formula: C₁₀H₁₆N₅O₁₄P₃•Nax•(H₂O)x

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 523.18 g/mol

Ref: 3D-NG30609

Guanosine 5′-triphosphate (trisodium salt)

CAS: 36051-31-7

Purity: 95%

Molecular weight: 589.94

Ref: 10-F554443

Guanosine-5'-triphosphate Trisodium Salt

CAS: 36051-31-7

Stability Hygroscopic
Applications Guanosine-5'-triphosphate Disodium Salt is one the substances used in GTP affinity probe for proteomics highlights flexibility in purine nucleotide selectivity for the study of GTP-binding proteins.
References George C., et al.: J. Am. Chem. Soc., 135, 4676 (2013)

Formula: C₁₀H₁₃N₅Na₃O₁₄P₃

Color and Shape: Neat

Molecular weight: 588.94

Ref: TR-G837905