CAS 3715-90-0

Tramazoline hydrochloride

Description:

Tramazoline hydrochloride is a pharmaceutical compound primarily used as a topical decongestant. It belongs to the class of imidazoline derivatives and functions by acting on alpha-adrenergic receptors, leading to vasoconstriction and reduced nasal congestion. The substance is typically administered in the form of nasal sprays or drops. Tramazoline hydrochloride is characterized by its white to off-white crystalline powder appearance, and it is soluble in water, which facilitates its use in aqueous formulations. The compound has a relatively low molecular weight and exhibits a moderate pKa, indicating its behavior as a weak base. Its pharmacological effects generally manifest within minutes of administration, providing rapid relief from nasal congestion. However, prolonged use can lead to rebound congestion, a phenomenon known as rhinitis medicamentosa. As with any medication, it is essential to use tramazoline hydrochloride according to medical guidelines to minimize potential side effects and ensure efficacy.

Formula: C₁₃H₁₇N₃·ClH

InChI: InChI=1S/C13H17N3.ClH/c1-2-6-11-10(4-1)5-3-7-12(11)16-13-14-8-9-15-13;/h3,5,7H,1-2,4,6,8-9H2,(H2,14,15,16);1H

InChI key: InChIKey=RZOXEODOFNEZRS-UHFFFAOYSA-N

SMILES: N(C1=C2C(=CC=C1)CCCC2)C=3NCCN3.Cl

Synonyms:

• 1H-Imidazol-2-amine, 4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-, hydrochloride (1:1)
• 1H-Imidazol-2-amine, 4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-, monohydrochloride
• 2-Imidazoline, 2-[(5,6,7,8-tetrahydro-1-naphthyl)amino]-, monohydrochloride
• Biciron
• Ellatun
• Kb 227
• N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-aminium chloride
• Rhinaspray
• Rhinogutt
• Rhinospray
• Rinogutt
• Tramazolin hydrochlorid x 1H20

Tramazoline

CAS: 1082-57-1, 3715-90-0

Formula: C₁₃H₁₇N₃

Molecular weight: 215.30

Ref: 4Z-T-262001

Tramazoline Acetate Salt

Controlled Product

CAS: 3715-90-0

Applications Tramazoline Acetate Salt is commonly used in nasal spray as a nasal decongestant by acting as an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koutsourelakis, I., et al.: Eur. Respir. J., 42, 1055-63 (2003);

Formula: C₁₃H₁₇N₃•C₂H₄O₂

Color and Shape: Neat

Molecular weight: 275.34

Ref: TR-T704800

Tramazoline hydrochloride

CAS: 3715-90-0

Tramazoline hydrochloride: a nasal decongestant in sprays, it's an α-adrenergic agonist reducing mucus secretion.

Formula: C₁₃H₁₈ClN₃

Color and Shape: Solid

Molecular weight: 251.76

Ref: TM-T69341