CAS 389-08-2: Nalidixic acid

Description: Nalidixic acid is a synthetic antibacterial agent belonging to the quinolone class of antibiotics. It is primarily used to treat urinary tract infections caused by susceptible bacteria. The compound is characterized by its bicyclic structure, which includes a naphthyridine ring system, and features a carboxylic acid functional group that contributes to its solubility and biological activity. Nalidixic acid exhibits broad-spectrum activity against Gram-negative bacteria, inhibiting bacterial DNA gyrase, an essential enzyme for DNA replication and transcription. Its pharmacokinetics include oral absorption, with peak plasma concentrations typically occurring within a few hours post-administration. The drug is metabolized in the liver and excreted primarily through the kidneys. Common side effects may include gastrointestinal disturbances and, in rare cases, central nervous system effects. Due to the emergence of bacterial resistance and the development of newer fluoroquinolones with improved efficacy and safety profiles, nalidixic acid is less commonly used today but remains a significant historical antibiotic in the treatment of specific infections.

Formula: C₁₂H₁₂N₂O₃

InChI: InChI=1S/C12H12N2O3/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14/h4-6H,3H2,1-2H3,(H,16,17)

InChI key: InChIKey=MHWLWQUZZRMNGJ-UHFFFAOYSA-N

SMILES: O=C(O)C1=CN(C2=NC(=CC=C2C1=O)C)CC

Synonyms:

• 1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
• 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-
• 1-Ethyl-1,4-Dihydro-7-Methyl-4-Oxo-1,8-Naphthyridine-3-Carboxylic Acid
• 1-Ethyl-7-Methyl-4-Oxo-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylate
• 1-Ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid
• 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid
• 1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
• 3-Carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one
• Acide Nalidixique
• Acido Nalidixico
• Betaxina
• Cetrimide Nalidixic acid Agar Supplement
• Cybis
• Dixiben
• Eucistin
• Innoxalomn
• Nacid
• Nalidic acid
• Nalidicron
• Nalidixan
• Nalidixicacid
• Nalidixin
• Nalidixinic acid
• Nalidixinsaure
• Nalidram
• Nalitucsan
• Nalix
• Nalurin
• Narigix
• Naxuril
• NegGram
• Nelidix
• Nevigramon
• Nicelate
• Nogram
• Nsc 82174
• Poleon
• Specifin
• Uralgin
• Uriben
• Uriclar
• Urisal
• Urodixin
• Uroman
• Uroneg
• Uropan
• Win 18320
• Wintomylon

Nalidixic Acid

CAS: 389-08-2

• Formula: C₁₂H₁₂N₂O₃
• Purity: >95.0%(T)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 232.24

Nalidixic acid, 99%

CAS: 389-08-2

Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent. It is also used as an inhibitor …

• Formula: C₁₂H₁₂N₂O₃
• Purity: 99%
• Color and Shape: White to pale cream to pale yellow, Powder
• Molecular weight: 232.24

1,8-Naphthyridine-3-carboxylic acid,1-ethyl-1,4-dihydro-7-methyl-4-oxo-

CAS: 389-08-2

• Formula: C₁₂H₁₂N₂O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 232.23527999999996

Nalidixic acid

CAS: 389-08-2

Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal …

• Formula: C₁₂H₁₂N₂O₃
• Purity: 99.22% - 99.95%
• Color and Shape: Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)
• Molecular weight: 232.24

Nalidixic acid

CAS: 389-08-2

• Formula: C₁₂H₁₂N₂O₃
• Color and Shape: Beige Powder
• Molecular weight: 232.24g/mol

Nalidixic acid, 99.5%

CAS: 389-08-2

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₂H₁₂N₂O₃
• Purity: 99.5%
• Color and Shape: White to light yellow, Powder
• Molecular weight: 232.24

Nalidixic acid 100 µg/mL in Acetonitrile

CAS: 389-08-2

• Formula: C₁₂H₁₂N₂O₃
• Color and Shape: Single Solution
• Molecular weight: 232.24

PharmaVetResiMix 3 Quinolones-v18 10 µg/mL in Methanol

CAS: 115550-35-1 119478-55-6 14698-29-4 149676-40-4 19562-30-2 28657-80-9 389-08-242835-25-6 51940-44-4 70458-96-7 74011-58-8 79660-72-3 82419-36-1 85721-33-1 91296-86-5 91296-87-6 93106-60-6 98079-52-8

• Color and Shape: Mixture

Nalidixic Acid

CAS: 389-08-2

• Formula: C₁₂H₁₂N₂O₃
• Color and Shape: Neat
• Molecular weight: 232.24

Nalidixic acid

CAS: 389-08-2

• Formula: C₁₂H₁₂N₂O₃
• Color and Shape: Neat
• Molecular weight: 232.24

GB/T 21312-2007 14 Quinolones 20 µg/mL in Methanol

CAS: 112398-08-0 14698-29-4 28657-80-9 389-08-242835-25-6 51940-44-4 70458-92-3 70458-96-7 74011-58-8 82419-36-1 85721-33-1 91296-87-6 93106-60-6 98079-52-8

• Color and Shape: Mixture

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3 113507-06-5 115550-35-1 117704-25-3 119478-55-6 122-11-2 1220-83-3 123997-26-2 127-71-9 127-79-7 144-82-1 144-83-2 14698-29-4 148-79-8 149676-40-4 155569-91-8 19562-30-2 20559-55-1 2447-57-6 28657-80-9 31430-15-6 31431-39-7 389-08-242835-25-6 43210-67-9 515-64-0 51940-44-4 53716-50-0 54029-12-8 54965-21-8 57-67-0 57-68-1 58306-30-2 59-40-5 63-74-1 651-06-9 68-35-9 68786-66-3 70288-86-7 70458-96-7 71751-41-2 72-14-0 723-46-6 729-99-7 74011-58-8 75184-71-3 79660-72-3 80-08-0 80-32-0 80-35-3 80983-34-2 82419-36-1 85721-33-1 88254-99-3 91296-86-5 91296-87-6 93106-60-6 948-71-0 98079-52-8

• Color and Shape: Mixture

Nalidixic acid 100 µg/mL in Methanol

CAS: 389-08-2

• Formula: C₁₂H₁₂N₂O₃
• Color and Shape: Single Solution
• Molecular weight: 232.24

Nalidixic acid

CAS: 389-08-2

• Formula: C₁₂H₁₂N₂O₃
• Purity: (Titration) 99.0 - 101.0 % (dried basis)
• Color and Shape: Almost white or pale yellow crystalline powder
• Molecular weight: 232.24

Nalidixic Acid

CAS: 389-08-2

Applications Antibacterial. References Bourguignon, G.J., et al.: Antimicrob. Agents Chemother., 4, 479 (1973), Grubb, P.E., …

• Formula: C₁₂H₁₂N₂O₃
• Color and Shape: Light Yellow
• Molecular weight: 232.24

1-Ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

CAS: 389-08-2

• Purity: 95.0%
• Color and Shape: Solid, No data available.
• Molecular weight: 232.23899841308594

Nalidixic acid

CAS: 389-08-2

Please enquire for more information about Nalidixic acid including the price, delivery time and more …

• Formula: C₁₂H₁₂N₂O₃
• Color and Shape: White Slightly Brown Powder
• Molecular weight: 232.24 g/mol

Nalidixic Acid free acid extrapure, 99%

CAS: 389-08-2

• Formula: C₁₂H₁₂N₂O₃
• Purity: min. 99%
• Color and Shape: White to pale yellow, Crystalline powder
• Molecular weight: 232.24