CAS: 404950-80-7 - 3-[4-[2-(2-Methyl-1H-indol-3-yl)ethylaminomethyl]phenyl]-2(E)-propenohydroxamic acid

Formula: C₂₁H₂₃N₃O₂

InChI: InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+

InChI key: InChIKey=FPOHNWQLNRZRFC-ZHACJKMWSA-N

SMILES: O=C(C=CC1=CC=C(C=C1)CNCCC=2C=3C=CC=CC3NC2C)NO

Synonyms:

• (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide
• (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide
• (E)-N-Hydroxy-3-(4-{[2-(2-Methyl-1H-Indol-3-Yl)-Ethylamino]-Methyl}-Phenyl)-Acrylamide
• 2-Propenamide, N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)-
• Farydak
• Lbh-589
• N-Hydroxy-3-[4-[2-(2-methyl-1H-indol-3-yl)ethylaminomethyl]phenyl]-2(E)-propenamide
• Nvp-Lbh-589
• Panobinostat

Panobinostat

CAS: 404950-80-7

• Formula: C₂₁H₂₃N₃O₂
• Purity: >93.0%(HPLC)
• Color and Shape: White to Light yellow to Light orange powder to crystal
• Molecular weight: 349.43

(2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide

CAS: 404950-80-7

• Formula: C₂₁H₂₃N₃O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 349.4262

Panobinostat

CAS: 404950-80-7

• Formula: C₂₁H₂₃N₃O₂
• Molecular weight: 349.43

Panobinostat

CAS: 404950-80-7

Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.

• Formula: C₂₁H₂₃N₃O₂
• Purity: 97.2% - 99.14%
• Color and Shape: Yellow Solid
• Molecular weight: 349.43

Panobinostat-d8 (Major) Hydrochloride Salt

CAS: 1185237-51-7 404950-80-7

Applications The novel labelled histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes …

• Formula: C₂₁H₁₆D₈ClN₃O₂
• Color and Shape: Neat
• Molecular weight: 393.94

Panobinostat(LBH-589)

CAS: 404950-80-7

Applications The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and …

• Formula: C₂₁H₂₃N₃O₂
• Color and Shape: Neat
• Molecular weight: 349.43

(E)-N-Hydroxy-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylamide

CAS: 404950-80-7

• Purity: 95.0%
• Color and Shape: Solid, White to off-white powder
• Molecular weight: 349.4339904785156

Panobinostat

CAS: 404950-80-7

Inhibitor of histone deacetylases

• Formula: C₂₁H₂₃N₃O₂
• Purity: Min. 97.5 Area-%
• Color and Shape: Off-White Slightly Brown Yellow Powder
• Molecular weight: 349.43 g/mol