CAS 4272-77-9

Dansyl acid

Description:

Dansyl acid, with the CAS number 4272-77-9, is a sulfonamide derivative known for its fluorescent properties, making it valuable in biochemical and analytical applications. It features a dansyl group, which is a 5-dimethylaminonaphthalene-1-sulfonyl moiety, contributing to its strong fluorescence. This compound is typically used as a labeling agent for amino acids and proteins, facilitating their detection and quantification in various assays. Dansyl acid is soluble in organic solvents such as methanol and dimethyl sulfoxide, but its solubility in water is limited. The compound exhibits a characteristic absorption and emission spectrum, which is essential for fluorescence-based techniques. Additionally, it can participate in various chemical reactions, including coupling with amines to form stable sulfonamide bonds. Due to its unique properties, dansyl acid is widely utilized in research fields such as biochemistry, molecular biology, and analytical chemistry, particularly in studies involving protein structure and function.

Formula: C₁₂H₁₃NO₃S

InChI: InChI=1/C12H13NO3S/c1-13(2)11-7-3-6-10-9(11)5-4-8-12(10)17(14,15)16/h3-8H,1-2H3,(H,14,15,16)/p-1

InChI key: InChIKey=BBEQQKBWUHCIOU-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)C=1C2=C(C(N(C)C)=CC=C2)C=CC1

Synonyms:

• 1-(Dimethylamino)-5-naphthalenesulfonic acid
• 1-Naphthalenesulfonic Acid, 5-(Dimethylamino)-
• 224-268-5
• 5-(Dimethylamino)-1-naphthalenesulfonic acid
• 5-(Dimethylamino)Naphthalene-1-Sulfonate
• 5-(Dimethylamino)Naphthalene-1-Sulfonic Acid
• 5-Dimethylamino-1-sulfonyl naphthalene
• Dansyl acid
• N,N-Dimethyl-1-naphthylamine-5-sulfonic acid
• 5-DIMETHYLAMINO-1-NAPHTHALENE
• 5-(Dimethylamino)-1-naphthalenesulfonic acid hydrate ,98%
• 1-(Dimethylamino)naphthalene-5-sulfonic acid
• 5-(Dimethylamino)
• 5-DIMETHYLAMINONAPHTHALENE-1-SULPHONIC ACID
• 5-DIMETHYLAMINONAPHTHALENE-1-SULFONIC ACID
• 5-(dimethylamino)-1-naphthalenesulfonicaci
• LABOTEST-BB LT00452749
• 5-(Dimethylamino)-1-naphthalenesulfonic acid hydrate,DNS
• DANSYL ACID 97%
• 5-Dimethylamino-1-naphthalenesulfonic acid, monohydrate,99%
• 1-DIMETHYLAMINONAPHTHALENE-5-SULPHONIC ACID
• 5-DIMETHYLAMINO-1-NAPHTHALENESULFONIC ACID MONOHYDRATE 99%
• Dansyl acid ,98%

5-(Dimethylamino)naphthalene-1-sulfonic acid

CAS: 4272-77-9

Formula: C₁₂H₁₃NO₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 251.3015

Ref: IN-DA003M7C

5-(Dimethylamino)naphthalene-1-sulfonic acid

CAS: 4272-77-9

5-(Dimethylamino)naphthalene-1-sulfonic acid

Purity: 98%

Ref: 54-OR1037080

Dansyl Acid

CAS: 4272-77-9

Formula: C₁₂H₁₃NO₃S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 251.30

Ref: 3B-D1426

5-(Dimethylamino)naphthalene-1-sulfonic acid

CAS: 4272-77-9

Purity: 98%

Molecular weight: 251.3000031

Ref: 10-F720785

Dansyl acid

CAS: 4272-77-9

Dansyl acid is a fatty acid that can be used as a fluorescent probe to study the binding of amines to receptors in human serum. Dansyl acid binds to amines by forming a covalent bond. It has been shown that the binding constants of dansyl acid are dependent on the pH, chloride concentration, and nitrogen atom content. The reaction mechanism of dansyl acid is proposed to involve an initial protonation step followed by nucleophilic attack. This process leads to a resonance-stabilized carbenium ion intermediate with two free electrons, which then quickly reacts with chloride ions or hydrochloric acid to form dansyl chloride or benzenesulfonic acid, respectively.

Formula: C₁₂H₁₃NO₃S

Purity: Min. 95%

Molecular weight: 251.3 g/mol

Ref: 3D-FD20785

Dansyl Acid

Controlled Product

CAS: 4272-77-9

Applications A fluorescent molecule used in protein analysis and FRET detection.
References Jarabak, R., et al.: J. Biochem. Toxicol., 5, 1 (1990), Fernandez-Tornero, C., et al.: J. Biol. Chem., 278, 21774 (2003), Mazooz, G., et al.: Canc. Res., 65, 1369 (2005),

Formula: C₁₂H₁₃NO₃S

Color and Shape: Neat

Molecular weight: 251.30

Ref: TR-D172860