CAS 458-24-2

Fenfluramine

Description:

Fenfluramine is a chemical compound primarily known for its use as an appetite suppressant in the treatment of obesity. It belongs to the class of phenethylamines and is structurally related to amphetamines. Fenfluramine acts primarily by increasing the levels of serotonin in the brain, which helps to reduce appetite. The substance is typically found as a white to off-white crystalline powder and is soluble in water and alcohol. Its mechanism of action involves the inhibition of serotonin reuptake and the release of serotonin from presynaptic neurons. Fenfluramine was once widely prescribed but was withdrawn from the market in many countries due to concerns about its association with serious cardiovascular side effects, including pulmonary hypertension and valvular heart disease. Despite its withdrawal, fenfluramine has been studied for other potential therapeutic uses, including in the treatment of certain neurological disorders. As with any pharmaceutical compound, its use should be carefully monitored and regulated due to its potential side effects and health risks.

Formula: C₁₂H₁₆F₃N

InChI: InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3

InChI key: InChIKey=DBGIVFWFUFKIQN-UHFFFAOYSA-N

SMILES: C(C(NCC)C)C1=CC(C(F)(F)F)=CC=C1

Synonyms:

• 3-(Trifluoromethyl)-N-ethyl-α-methylphenethylamine
• <span class="text-smallcaps">DL</span>-Fenfluramine
• Acino
• Benzeneethanamine, N-ethyl-α-methyl-3-(trifluoromethyl)-
• DL-Fenfluramine
• Ethyl(Alpha-Methyl-3-Trifluoromethylphenethyl)Amine
• Fenfluramin
• Fenfluramina
• N-Ethyl-α-methyl-3-(trifluoromethyl)benzeneethanamine
• N-Ethyl-α-methyl-3-(trifluoromethyl)phenethylamine
• Obedrex
• Pesos
• Phenethylamine, N-ethyl-α-methyl-m-(trifluoromethyl)-
• Ponderax PA
• Rotondin

Fenfluramine

CAS: 458-24-2

Formula: C₁₂H₁₆F₃N

Color and Shape: Colorless Liquid

Molecular weight: 231.26

Ref: 4Z-F-108015

Fenfluramine-d5

CAS: 458-24-2

Formula: C₁₂H₁₁F₃ND₅

Molecular weight: 236.29

Ref: 4Z-F-108002

DL-Fenfluramine

Controlled Product

CAS: 458-24-2

Applications Anorectic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pinder, et al.: Drugs, 10, 241 (1975); Caccia, S., et al.: Eur. J. Clin. Pharmacol., 29, 221 (1985); Finner, N., et al.: Curr. Ther. Res., 38, 847 (1985);

Formula: C₁₂H₁₆F₃N

Color and Shape: Neat

Molecular weight: 231.26

Ref: TR-F247600