CAS: 481-49-2 - cepharanthine

Formula: C₃₇H₃₈N₂O₆

InChI: InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1

InChI key: InChIKey=YVPXVXANRNDGTA-WDYNHAJCSA-N

SMILES: O1C2=CC=C(C=C2)CC3C4=C(OC=5C=C6C(=CC5OC)CCN(C)C6CC7=CC=C(OC)C1=C7)C=8OCOC8C=C4CCN3C

Synonyms:

• (14S,27R)-22,33-dimethoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.2~16,19~.1~3,10~.1~21,25~.0~4,8~.0~14,39~.0~31,35~]nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-dodecaene (non-preferred name)
• (14aS,26aR)-2,3,13,14,14a,15,26,26a-Octahydro-22,30-dimethoxy-1,14-dimethyl-1H-4,6:16,19-dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline
• 1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline, 2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, (14aS,26aR)-
• 1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2′,3′:17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline, 2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, [14aS-(14aR*,26aS*)]-
• 22,33-Dimethoxy-13,28-Dimethyl-2,5,7,20-Tetraoxa-13,28-Diazaoctacyclo[25.6.2.2~16,19~.1~3,10~.1~21,25~.0~4,8~.0~14,39~.0~31,35~]Nonatriaconta-1(33),3,8,10(39),16,18,21(36),22,24,31,34,37-Dodecaene (Non-Preferred Name)
• Cepharanthin
• Cepharantin
• NSC 623442
• O-Methylcepharanoline
• Oxyacanthan, 6′,12′-dimethoxy-2,2′-dimethyl-6,7-[methylenebis(oxy)]-
• Sml 1269
• Stephanotis

1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline,2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-,(14aS,26aR)-

CAS: 481-49-2

• Formula: C₃₇H₃₈N₂O₆
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 606.7074

Cepharanthine

CAS: 481-49-2

Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid …

• Formula: C₃₇H₃₈N₂O₆
• Purity: 99.95%
• Color and Shape: Yellow Powder
• Molecular weight: 606.71

Cepharanthine

CAS: 481-49-2

• Formula: C₃₇H₃₈N₂O₆
• Purity: ≥ 95.0%
• Color and Shape: White to off-white or beige powder
• Molecular weight: 606.71

Cepharanthine

CAS: 481-49-2

• Formula: C₃₇H₃₈N₂O₆
• Purity: >90.0%(T)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 606.72

Cepharanthine

CAS: 481-49-2

• Formula: C₃₇H₃₈N₂O₆
• Purity: 95%~99%
• Molecular weight: 606.719

Cepharanthine

CAS: 481-49-2

Natural alkaloid

• Formula: C₃₇H₃₈N₂O₆
• Purity: ≥ 98.0 % (HPLC)
• Color and Shape: Powder
• Molecular weight: 606.72

Cepharanthine

CAS: 481-49-2

Applications Cepharanthine is a biscoclaurine alkaloid that has antiinflammatory and other biological functions.

• Formula: C₃₇H₃₈N₂O₆
• Color and Shape: Off-White to Pale Yellow Solid
• Molecular weight: 606.71

Cepharanthine

CAS: 481-49-2

Competes with eNOS for binding to HSP90α

• Formula: C₃₇H₃₈N₂O₆
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 606.71 g/mol