CAS 51186-83-5

erythro-Glycopyrronium bromide

Description:

Erythro-Glycopyrronium bromide is a synthetic quaternary ammonium compound primarily used for its anticholinergic properties. It is characterized by its ability to inhibit the action of acetylcholine at muscarinic receptors, leading to reduced secretions and smooth muscle relaxation. This compound is often utilized in the management of conditions such as chronic obstructive pulmonary disease (COPD) and excessive sweating. Erythro-Glycopyrronium bromide is typically administered via inhalation or topical formulations, depending on the therapeutic application. Its chemical structure includes a glycopyrrolate backbone, which contributes to its pharmacological effects. The bromide ion serves as a counterion, enhancing the solubility and stability of the compound. In terms of safety, like other anticholinergics, it may cause side effects such as dry mouth, blurred vision, and urinary retention. Overall, erythro-Glycopyrronium bromide represents a valuable therapeutic agent in respiratory and dermatological treatments, with ongoing research exploring its broader applications in medicine.

Formula: C₁₉H₂₈NO₃·Br

InChI: InChI=1/C19H28NO3.BrH/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15;/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3;1H/q+1;/p-1/t17-,19-;/s2

InChI key: InChIKey=VPNYRYCIDCJBOM-HPUDQCTANA-M

SMILES: [C@@](C(O[C@@H]1C[N+](C)(C)CC1)=O)(O)(C2CCCC2)C3=CC=CC=C3.[Br-]

Synonyms:

• Pyrrolidinium, 3-[(cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethyl-, bromide, (R*,S*)-(±)-
• Ritropirronium bromide
• erythro-Glycopyrronium bromide
• Pyrrolidinium, 3-[[(2R)-2-cyclopentyl-2-hydroxy-2-phenylacetyl]oxy]-1,1-dimethyl-, bromide (1:1), (3S)-rel-
• Pyrrolidinium, 3-[[(2R)-cyclopentylhydroxyphenylacetyl]oxy]-1,1-dimethyl-, bromide, (3S)-rel-

Glycopyrronium Bromide

CAS: 51186-83-5

Color and Shape: Neat

Ref: 61-FOR0834.00

GLYCOPYRRONIUM FOR PEAK IDENTIFICATION CRS

CAS: 51186-83-5

GLYCOPYRRONIUM FOR PEAK IDENTIFICATION CRS

Formula: C₁₉H₂₈BrNO₃

Color and Shape: Powder

Molecular weight: 398.3345

Ref: 41-Y0001309

Glycopyrronium bromide

CAS: 51186-83-5

Glycopyrronium bromide

Formula: C₁₉H₂₈BrNO₃

Purity: 99.9%

Color and Shape: White

Molecular weight: 397.12526

Ref: 47-1110

GLYCOPYRRONIUM BROMIDE CRS

CAS: 51186-83-5

GLYCOPYRRONIUM BROMIDE CRS

Formula: C₁₉H₂₈BrNO₃

Color and Shape: Powder

Molecular weight: 398.3345

Ref: 41-Y0001308

Glycopyrrolate

CAS: 51186-83-5

Drugs with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Formula: C₁₉H₂₈BrNO₃

Color and Shape: White Powder

Molecular weight: 397.12526

Ref: 45-1296009

Glycopyrronium Bromide

Controlled Product

CAS: 51186-83-5

Formula: C₁₉H₂₈NO₃·Br

Color and Shape: Neat

Molecular weight: 398.33

Ref: 86-MM0834.00

N-Nitroso Glycopyrrolate Impurity 29

CAS: 51186-83-5, 596-51-0

Formula: C₁₇H₂₂N₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 318.37

Ref: 4Z-G-3251

erythro-Glycopyrronium bromide

CAS: 51186-83-5

Erythro-Glycopyrronium bromide is a quaternary ammonium anticholinergic drug with clinical use in the treatment of pulmonary disease. It acts by blocking the action of acetylcholine at the muscarinic acetylcholine receptor. Erythro-Glycopyrronium bromide has been shown to be safe and effective in human clinical trials, with no adverse effects on heart rate or blood pressure. This drug has a long duration of action and is an enantiomer of glycopyrrolate. The erythro form is more potent than the threo form, which is used clinically as an antispasmodic agent for gastrointestinal disorders.

Formula: C₁₉H₂₈NO₃·Br

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 398.33 g/mol

Ref: 3D-FG166398