CAS 54-85-3
:Isoniazid
Description:
Isoniazid, with the CAS number 54-85-3, is an organic compound primarily used as an antibiotic in the treatment of tuberculosis. It is a pyridine derivative, specifically a hydrazide of isonicotinic acid, and has the molecular formula C6H6N4O. Isoniazid is characterized by its ability to inhibit the synthesis of mycolic acids, essential components of the bacterial cell wall in Mycobacterium tuberculosis. This mechanism of action makes it effective against tuberculosis bacteria. The compound is typically administered orally and is known for its relatively good absorption and distribution in the body. Isoniazid can have side effects, including hepatotoxicity and peripheral neuropathy, which necessitate monitoring during treatment. It is often used in combination with other antitubercular agents to prevent the development of drug resistance. Additionally, isoniazid is a weak base and is soluble in water, which facilitates its use in clinical settings. Its effectiveness and relatively low cost have made it a cornerstone in tuberculosis therapy worldwide.
Formula:C6H7N3O
InChI:InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
InChI key:InChIKey=QRXWMOHMRWLFEY-UHFFFAOYSA-N
SMILES:C(NN)(=O)C=1C=CN=CC1
Synonyms:- 4-(Hydrazinocarbonyl)pyridine
- 4-(Hydrazinomethyl)Pyridine
- 4-Pyridinecarbonylhydrazine
- 4-Pyridylcarbonylhydrazide
- Antimicina
- Armazid
- Armazide
- Atcotibine
- Cedin
- Cotinazin
- Dianicotyl
- Dinacrin
- Ditubin
- Eralon
- Ertuban
- Eutizon
- Gink
- HIA
- Hidranizil
- Hidrasonil
- Hycozid
- Hydrazid
- Hyzyd
- Inah
- Ipcazide
- Isidrina
- Isobicina
- Isocaldin
- Isocid
- Isocotin
- Isokin
- Isolyn
- Isonex
- Isoniazid
- Isoniazida
- Isoniazide
- Isonicid
- Isonico
- Isonicotan
- Isonicotinohydrazide
- Isonicotinoylhydrazine
- Isonicotinsaeure-Hydrazid
- Isonicotinylhydrazide
- Isonidrin
- Isonilex
- Isonindon
- Isonizide
- Isotebezid
- Isozide
- Isozin
- Isozyd
- Lafepe
- Laniazid
- Mayambutol
- Mybasan
- Neoteben
- Neoxin
- Neumandin
- Nevin
- Niadrin
- Nicetal
- Nicizina
- Niconyl
- Nicotibina
- Nicotisan
- Nicozide
- Nidaton
- Nidrazid
- Nikozid
- Niplen
- Nitadon
- Nydrazid
- Nyscozid
- Pelazid
- Pycazide
- Pyricidin
- Pyridine-3-Carbohydrazide
- Pyridine-4-carbohydrazide
- Pyrizidin
- RU-EF-Tb
- Raumanon
- Retozide
- Rimicid
- Rimifon
- Rimiphone
- Rimitsid
- Robisellin
- Sauterazid
- Solonex
- TB-Vis
- Tebecid
- Teebaconin
- Tekazin
- Tibinide
- Tibizide
- Tisin
- Tisiodrazida
- Tizide
- Tubazid
- Tubazide
- Tubeco
- Tubicon
- Tubilysin
- Tubomel
- Tyvid
- Unicozyde
- Vazadrine
- Vederon
- Zidafimia
- Zinadon
- Zonazide
- [(4-Pyridinylcarbonyl)oxy]hydrazine
- 5015 R.P.
- Isonicotinic hydrazide
- Isonicotinic acid hydrazide
- 4-Pyridinecarboxylic acid, hydrazide
- FSR 3
- See more synonyms
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Isonicotinic acid hydrazide, 98+%
CAS:Used for fluorescent HPLC detection of delta 4-3-ketosteroids This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference hFormula:C6H7N3OPurity:98+%Color and Shape:White to pale cream, Powder or crystalsMolecular weight:137.14Isoniazid
CAS:IsoniazidFormula:C6H7N3OPurity:99.7%Color and Shape:White. To. Off-WhiteMolecular weight:137.05891ISONIAZID CRS
CAS:ISONIAZID CRSFormula:C6H7N3OColor and Shape:Crystalline Powder. White. Colourless Crystals. Powder.Molecular weight:137.1393Isoniazid
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C6H7N3OColor and Shape:Colorless White Crystalline PowderMolecular weight:137.15 g/molIsoniazid
CAS:Isoniazid (Isonicotinic hydrazide) is an antibacterial agent used primarily as a tuberculostatic.Formula:C6H7N3OPurity:99.21% - 99.79%Color and Shape:SolidMolecular weight:137.144-Pyridinecarboxylic acid, hydrazide
CAS:Formula:C6H7N3OPurity:%Color and Shape:SolidMolecular weight:137.1393Ref: IN-DA00I9N2
10g23.00€25g23.00€100g25.00€50g30.00€200g49.00€300g57.00€500g66.00€1kg127.00€1000g129.00€5kg345.00€Isoniazid, EP grade
CAS:Formula:C6H7N3OPurity:99.0 - 101.0 % (dried substance)Color and Shape:White or almost white crystalline powder, or colourless crystalsMolecular weight:137.14Isoniazid
CAS:Formula:C6H7N3OPurity:(Titration) ≥ 98.5% (dried basis)Color and Shape:White to off-white crystalline powderMolecular weight:137.14Isonicotinic Acid Hydrazide
CAS:Formula:C6H7N3OPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:137.14Pyridine-4-carbohydrazide
CAS:Pyridine-4-carbohydrazideFormula:C6H7N3OPurity:98%Color and Shape:White Solid-PowderMolecular weight:137.13928Isoniazid
CAS:Controlled ProductApplications Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic).
References Brewer, G.A., et al.: Anal. Profiles Drug Subs., 6, 183 (1977), Weber, W.W., et al.: Clin. Pharmacokinet., 4, 401 (1979)Formula:C6H7N3OColor and Shape:NeatMolecular weight:137.14lsoniazid
CAS:Lysostaphin is an antimicrobial enzyme with a mode of action that cleaves the cell wall of Staphylococcus aureus. It is used for treating staphylococcal infections and in research applications.Formula:C6H7N3OPurity:Min. 95%Color and Shape:White PowderMolecular weight:137.14 g/mol
