CAS 56-75-7: (-)-Chloramphenicol

Description: (-)-Chloramphenicol, with the CAS number 56-75-7, is a broad-spectrum antibiotic originally derived from the bacterium Streptomyces venezuelae. It is characterized by its ability to inhibit bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome, effectively blocking peptide bond formation. This compound is a white to off-white crystalline powder that is soluble in water and alcohol but has limited solubility in organic solvents. Its molecular formula is C11H12Cl2N2O5, and it has a molecular weight of approximately 323.13 g/mol. (-)-Chloramphenicol exhibits antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. However, its use is limited due to potential side effects, including aplastic anemia and gray baby syndrome in newborns. As a result, it is often reserved for serious infections where other antibiotics are ineffective. Proper handling and dosage are crucial to minimize adverse effects and ensure therapeutic efficacy.

Formula: C₁₁H₁₂Cl₂N₂O₅

InChI: InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1

InChI key: InChIKey=WIIZWVCIJKGZOK-RKDXNWHRSA-N

SMILES: O=C(NC(CO)C(O)C1=CC=C(C=C1)N(=O)=O)C(Cl)Cl

Synonyms:

• 2,2-Dichloro-N-(2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl)-Acetamid
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-Dichloro-N-[2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-dichloro-N-[(1R,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• 2,2-dichloro-N-[(1S,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• Ak-Chlor
• Alficetyn
• Amphenicol
• Amphicol
• Amseclor
• Anacetin
• Aquamycetin
• Austracol
• Bradyoxetin
• CAF
• CAM
• CAP
• CPh
• Catilan
• Chemicetin
• Chemicetina
• Chlomycol
• Chloramex
• Chloramphenicol
• Chloramsaar
• Chlorasol
• Chlorcetin
• Chloricol
• Chlorocaps
• Chlorocid
• Chlorocide
• Chlorocin
• Chloromycetin
• Chloronitrin
• Chloroptic
• Ciplamycetin
• Cloramfen
• Cloramfenicol
• Cloramficin
• Cloramicol
• Clorocyn
• Cloromisan
• Cylphenicol
• D-(-)-Chloramphenicol
• D-(-)-Threo-2,2-Dichloro-N-[Beta-Hydroxy-Alpha-(Hydroxy-Methyl)-P-Nitrophenethyl]Acetamide
• D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol
• D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol
• D-(-)-threo-Chloramphenicol
• D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol
• D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
• Detreomycin
• Embacetin
• Enicol
• Enteromycetin
• Farmicetina
• Fenicol
• Globenicol
• Gloveticol
• Halcetin
• Intramycetin
• Ismicetina
• Juvamycetin
• Kamaver
• Kemicetine
• Klorita
• Leukomyan
• Leukomycin
• Levocin
• Levomicetina
• Levomitsetin
• Levomycetin
• Levoplast
• Levosin
• Levovetin
• Loromisin
• Mastiphen
• Micloretin
• Micoclorina
• Microcetina
• Mychel
• Mychel-Vet
• Mycinol
• Myclocin
• Mycochlorin
• Novomycetin
• Ocuphenicol
• Opclor
• Ophthochlor
• Pantovernil
• Paraxin
• Quemicetina
• Ronphenil
• Septicol
• Sintomicetin
• Sintomicetina
• Soluthor
• Stanomycetin
• Synthomycetin
• Synthomycin
• Tevcocin
• Tifomycine
• Treomicetina
• Unimycetin
• Veticol
• Viceton
• [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• D,L-chloramphenicol
• Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-
• nitrophenyl)ethyl]acetamide
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-

Chloramphenicol

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 323.13

(R,R)-Chloramphenicol, 98%

CAS: 56-75-7

Inhibitor of translation on the 50S subunit at the peptidyltransferase step. (R,R)-Chloramphenicol is widely utilized …

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: 98%
• Color and Shape: Crystals or powder or crystalline powder, White to yellow to cream to grey
• Molecular weight: 323.13

Chloramphenicol

CAS: 56-75-7

• Purity: 97.0%
• Color and Shape: Solid, Powder or Crystalline Powder or Needles
• Molecular weight: 323.1300048828125

Chloramphenicol

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: 97.68%
• Color and Shape: Colorless. Oil
• Molecular weight: 322.0

Chloramphenicol

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: 100.0%
• Color and Shape: Off-White
• Molecular weight: 322.01233

Chloramphenicol CRS

CAS: 56-75-7

Chloramphenicol for peak identification CRS

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Color and Shape: White. Whitish. Crystalline Powder. Powder.
• Molecular weight: 323.1294

Chloramphenicol RS

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Molecular weight: 323.1294

Chloramphenicol

CAS: 56-75-7

Chloramphenicol and its derivatives; salts thereof

• Formula: C₁₁H₁₂Cl₂N₂₀₅
• Color and Shape: White Powder
• Molecular weight: 3084.66178

Chloramphenicol

CAS: 56-75-7

Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and …

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: 99.6% - 99.84%
• Color and Shape: Needles Or Elongated Plates From Water Or Ethylene Dichloride Solid
• Molecular weight: 323.13

Chloramphenicol, USP grade, low endotoxin

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: 97.0 - 103.0 %
• Color and Shape: White to light-yellow crystalline powder
• Molecular weight: 323.14

Chloramphenicol, Ph. Eur. grade

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: (dried basis) 98.0 - 102.0 %
• Color and Shape: A white, greyish-white or yellowish-white, fine, crystalline powder or crystals
• Molecular weight: 323.14

Chloramphenicol

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: 98.5 - 101.5 % (dried basis)
• Color and Shape: White to light-yellow crystalline powder
• Molecular weight: 323.14

Chloramphenicol-d4

CAS: 56-75-7

• Formula: C₁₁H₈D₄Cl₂N₂O₅
• Color and Shape: Pale Yellow Solid
• Molecular weight: 327.15

Chloramphenicol, 98%

CAS: 56-75-7

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: 98%
• Color and Shape: White to yellowish-white to greyish-white, Crystalline powder
• Molecular weight: 323.13

Chloramphenicol

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Color and Shape: Neat
• Molecular weight: 323.13

Chloramphenicol 100 µg/mL in Ethyl acetate

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Color and Shape: Single Solution
• Molecular weight: 323.13

Chloramphenicol 10 µg/mL in Acetonitrile

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Color and Shape: Single Solution
• Molecular weight: 323.13

Chloramphenicol

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Color and Shape: Neat
• Molecular weight: 323.13

Chloramphenicol

CAS: 56-75-7

• Formula: C₁₁H₁₂Cl₂N₂O₅
• Purity: >99%
• Color and Shape: solid
• Molecular weight: 323.13g/mol