CAS 565453-40-9

(2S)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carboxylic acid

Description:

The chemical substance known as (2S)-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carboxylic acid, with the CAS number 565453-40-9, is a synthetic compound that belongs to the class of amino acids and derivatives. It features a pyrrolidine ring, which is a five-membered nitrogen-containing heterocycle, and is characterized by the presence of a carboxylic acid functional group, an amino group, and a hydroxy group attached to an adamantyl moiety. This structure contributes to its potential biological activity, particularly in the context of medicinal chemistry, where it may exhibit properties relevant to drug design. The stereochemistry indicated by the (2S) designation suggests that the compound has specific spatial arrangements that can influence its interactions with biological targets. Additionally, the presence of the adamantyl group may enhance lipophilicity, potentially affecting the compound's pharmacokinetics and bioavailability. Overall, this compound's unique structural features make it a subject of interest for further research in pharmaceutical applications.

Formula: C₁₇H₂₆N₂O₄

InChI: InChI=1/C17H26N2O4/c20-14(19-3-1-2-13(19)15(21)22)9-18-16-5-11-4-12(6-16)8-17(23,7-11)10-16/h11-13,18,23H,1-10H2,(H,21,22)/t11?,12?,13-,16?,17?/m0/s1

SMILES: C1C[C@@H](C(=O)O)N(C1)C(=O)CNC12CC3CC(C1)CC(C3)(C2)O

N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline

CAS: 565453-40-9

Formula: C₁₇H₂₆N₂O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 322.3993

Ref: IN-DA0038MT

Vildagliptin carboxylic acid metabolite

CAS: 565453-40-9

Vildagliptin carboxylic acid metabolite

Purity: 97%

Molecular weight: 322.4g/mol

Ref: 54-OR1007117

Vildagliptin Carboxylic Acid Impurity

CAS: 565453-40-9

Formula: C₁₇H₂₆N₂O₄

Molecular weight: 322.40

Ref: ST-EA-CP-V1007

Vildagliptin Carboxylic Acid Lithium Salt Hydrate

Controlled Product

CAS: 565453-40-9

Applications The major metabolite of Vildagliptin (V305000).
References Reimer, M.K., et al.: Eur. J. Endocrinol., 146, 717 (2002), Villhauer, E.B., et al.: J. Med. Chem., 46, 2774 (2003), Ahren, B., et al.: J. Clin. Endocrinol. Metab., 85, 2078 (2004), He, H., et al.: Drug Metab. Dispos., 37, 545 (2009),

Formula: C₁₇H₂₅LiN₂O₄

Color and Shape: Neat

Molecular weight: 328.33

Ref: TR-V305015

N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline

Controlled Product

CAS: 565453-40-9

Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline, is a metabolite of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase.
References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

Formula: C₁₇H₂₆N₂O₄

Color and Shape: Neat

Molecular weight: 322.399

Ref: TR-H296965

N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline

CAS: 565453-40-9

Purity: 97%

Molecular weight: 322.4049988

Ref: 10-F862471