CAS 570-62-7

(3α,5β,12β)-3,12-Dihydroxycholan-24-oic acid

Description:

(3α,5β,12β)-3,12-Dihydroxycholan-24-oic acid, commonly known as chenodeoxycholic acid, is a bile acid that plays a crucial role in the digestion and absorption of dietary fats and fat-soluble vitamins in the intestine. It is a steroid acid derived from cholesterol and is characterized by its hydroxyl groups at the 3 and 12 positions, which contribute to its amphipathic nature, allowing it to emulsify fats. This compound is typically found in the bile of mammals and is involved in the regulation of cholesterol metabolism. Chenodeoxycholic acid has therapeutic applications, particularly in the treatment of certain types of gallstones and as a cholesterol-lowering agent. Its molecular structure includes a steroid backbone with a carboxylic acid functional group, which enhances its solubility in aqueous environments. Additionally, it exhibits biological activities that influence lipid metabolism and has been studied for its potential effects on liver function and cholesterol homeostasis.

Formula: C₂₄H₄₀O₄

InChI: InChI=1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21-,23+,24-/m1/s1

InChI key: InChIKey=KXGVEGMKQFWNSR-MFSKYVBHSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(C[C@H]1O)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Synonyms:

• (3α,5β,12β)-3,12-Dihydroxycholan-24-oic acid
• 12-Epideoxycholic acid
• 12-epi-Deoxycholic acid
• 3a,12b-Dihydroxy-5b-cholan-24-oic acid
• 3a,12b-Dihydroxy-5b-cholanicacid
• 3a,12b-Dihydroxy-5b-cholanoic acid
• 3a,12b-Dihydroxycholanoic acid
• 3α,12β-Dihydroxy-5β-cholanic acid
• 5b-Cholan-24-oic acid, 3a,12b-dihydroxy- (8CI)
• 5b-Cholanic acid, 3a,12b-dihydroxy- (7CI)
• 5β-Cholan-24-oic acid, 3α,12β-dihydroxy-
• 5β-Cholanic acid, 3α,12β-dihydroxy-
• Cholic acid, 12-epi-deoxy-

3α,12β-Dihydroxycholanoic acid

CAS: 570-62-7

3α,12β-Dihydroxycholanoic acid

Purity: 96%

Molecular weight: 392.57g/mol

Ref: 54-OR1001755

Cholic Acid Impurity 27

CAS: 570-62-7

Formula: C₂₄H₄₀O₄

Color and Shape: White To Off-White Solid

Molecular weight: 392.58

Ref: 4Z-C-5743

Lagodeoxycholic Acid

CAS: 570-62-7

Formula: C24H40O4

Purity: >98%

Color and Shape: Solid

Molecular weight: 392.57

Ref: 48-65-1104

3α,12β-Dihydroxycholanoic acid

CAS: 570-62-7

3α,12β-Dihydroxycholanoic acid, a bile acid, can be isolated from urine specimens of healthy humans.

Formula: C₂₄H₄₀O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 392.57

Ref: TM-T13505

3a,12b-Dihydroxycholanoic Acid

Controlled Product

CAS: 570-62-7

Applications 3α,12β-Dihydroxycholanoic Acid is a bile acid that may decrease of the toxic effects of deoxycholic acid on lipid peroxidn.
References Hino, A., et. al.: J. Biochem., 129, 683 (2001)

Formula: C₂₄H₄₀O₄

Color and Shape: Neat

Molecular weight: 392.57

Ref: TR-D447440

(R)-4-((3R,5R,8R,9S,10S,12R,13R,14S,17R)-3,12-DIHYDROXY-10,13-DIMETHYLHEXADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL)PENTANOIC ACID

CAS: 570-62-7

Purity: 99%

Molecular weight: 392.5799866

Ref: 10-F808649

3±,12²-Dihydroxycholanoic acid

Controlled Product

CAS: 570-62-7

3±,12²-Dihydroxycholanoic acid is a non-steroidal anti-inflammatory drug that inhibits the synthesis of prostaglandins in the body. It is used to treat bowel disease and inflammatory diseases such as Crohn's disease and ulcerative colitis. 3±,12²-Dihydroxycholanoic acid causes decreased transport rates in the intestine and may have beneficial effects on cancer cells. The drug is also effective against HIV infection, which may be due to its ability to inhibit protein synthesis in the virus.

Formula: C₂₄H₄₀O₄

Purity: Min. 95%

Molecular weight: 392.57 g/mol

Ref: 3D-AAA57062

3α,12β-Dihydroxycholanoic Acid

CAS: 570-62-7

Formula: C₂₄H₄₀O₄

Molecular weight: 392.58

Ref: ST-EA-CP-U1013