CAS 62893-19-0: Cefoperazone

Description: Cefoperazone is a broad-spectrum cephalosporin antibiotic, classified under the third generation of cephalosporins. It is primarily used to treat a variety of bacterial infections, particularly those caused by Gram-negative bacteria, including Pseudomonas aeruginosa. Cefoperazone is characterized by its beta-lactam structure, which is essential for its antibacterial activity. It is typically administered via injection, as it is poorly absorbed from the gastrointestinal tract. The compound is known for its stability against certain beta-lactamases, making it effective against resistant strains. Cefoperazone has a relatively long half-life, allowing for less frequent dosing compared to some other antibiotics. It is often used in combination with other antibiotics to enhance its efficacy and broaden its spectrum of activity. Common side effects may include gastrointestinal disturbances, allergic reactions, and alterations in liver function tests. As with all antibiotics, it is crucial to use cefoperazone judiciously to minimize the risk of developing antibiotic resistance.

Formula: C₂₅H₂₇N₉O₈S₂

InChI: InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1

InChI key: InChIKey=GCFBRXLSHGKWDP-XCGNWRKASA-N

SMILES: O=C(O)C1=C(CSC2=NN=NN2C)CSC3N1C(=O)C3NC(=O)C(NC(=O)N4C(=O)C(=O)N(CC)CC4)C5=CC=C(O)C=C5

Synonyms:

• (6R,7R)-7-[[(2R)-2-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2S)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, [6R-[6α,7β(R*)]]-
• Biocefazon
• Cefob
• Cefobid
• Cefoperazine
• Cefoperazon
• Cefoperazone,sodium salt
• Cefoperazono
• Cefozon
• Cephaperazon
• Medocef
• sodium 7-{[{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}(4-hydroxyphenyl)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Cefoperazone

Cefoperazone

CAS: 62893-19-062893-20-3

• Formula: C₂₅H₂₇N₉O₈S₂
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 645.67

Cefoperazone dihydrate CRS

CAS: 62893-19-0

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,(6R,7R)-

CAS: 62893-19-0

• Formula: C₂₅H₂₇N₉O₈S₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 645.6674

Cefoperazone

CAS: 62893-19-0

• Purity: 99.4%
• Molecular weight: 645.67g/mol

Cefoperazone

CAS: 62893-19-0

• Formula: C₂₅H₂₇N₉O₈S₂·xH₂O
• Purity: ≥ 95.0% (anhydrous basis)
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 645.66 (anhydrous)

Cefoperazone

CAS: 62893-19-0

• Formula: C₂₅H₂₇N₉O₈S₂
• Molecular weight: 645.67

Cefoperazone 1000 µg/mL in Acetonitrile

CAS: 62893-19-0

• Formula: C₂₅H₂₇N₉O₈S₂
• Color and Shape: Single Solution
• Molecular weight: 645.67

Cefoperazone

CAS: 62893-19-0

Cefoperazone (Medocef) inactivates PBPs, disrupting bacterial cell wall synthesis and division; inhibits rMrp2 [3H]E217βG uptake …

• Formula: C₂₅H₂₇N₉O₈S₂
• Purity: 98.99% - 99.41%
• Color and Shape: Solid
• Molecular weight: 645.67

Cefoperazone RS

CAS: 62893-19-0

• Color and Shape: White To Slightly Pale Yellow Solid Crystal To Powder

Cefoperazone Acid

CAS: 62893-19-0

Applications Cefoperazone acid is an antimicrobial β-lactamase inhibitor. References Ou, W., et al.: Zhongguo Linchuang …

• Formula: C₂₅H₂₇N₉O₈S₂
• Color and Shape: Neat
• Molecular weight: 645.67

Cefoperazone free acid

CAS: 62893-19-0

Please enquire for more information about Cefoperazone free acid including the price, delivery time and …

• Formula: C₂₅H₂₇N₉O₈S₂
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 645.67 g/mol

Cefoperazone N-Ethyl-d5

CAS: 62893-19-0

• Formula: C₂₅D₅H₂₂N₉O₈S₂
• Color and Shape: Neat
• Molecular weight: 650.698

Cefoperazone N-Methyl-d3

CAS: 62893-19-0

• Formula: C₂₅D₃H₂₄N₉O₈S₂
• Color and Shape: Neat
• Molecular weight: 648.686