CAS 85-73-4

Phthalylsulfathiazole

Description:

Phthalylsulfathiazole, with the CAS number 85-73-4, is a sulfonamide antibiotic that is primarily used for its antibacterial properties. It is characterized by its chemical structure, which includes a phthalyl group and a sulfathiazole moiety, contributing to its efficacy against a range of bacterial infections. This compound is typically administered orally and is known for its ability to inhibit bacterial growth by interfering with folic acid synthesis, a vital process for bacterial proliferation. Phthalylsulfathiazole is often utilized in veterinary medicine, particularly for treating gastrointestinal infections in animals. Its solubility in water is limited, which can affect its absorption and bioavailability. Additionally, it may exhibit side effects common to sulfonamides, such as allergic reactions or gastrointestinal disturbances. Due to its specific applications and potential side effects, the use of phthalylsulfathiazole is regulated, and it is important to follow appropriate guidelines when prescribing or administering this antibiotic.

Formula: C₁₇H₁₁N₃O₄S₂

InChI: InChI=1/C15H14N2O5S.C3H3NS/c1-16-23(21,22)11-8-6-10(7-9-11)17-14(18)12-4-2-3-5-13(12)15(19)20;1-2-5-3-4-1/h2-9,16H,1H3,(H,17,18)(H,19,20);1-3H

InChI key: InChIKey=PBMSWVPMRUJMPE-UHFFFAOYSA-N

SMILES: C(NC1=CC=C(S(NC2=NC=CS2)(=O)=O)C=C1)(=O)C3=C(C(O)=O)C=CC=C3

Synonyms:

• (o-Carboxybenzoyl)-p-aminophenylsulfonamidothiazole
• 2-(N⁴-Phthalylaminobenzenesulfonamide)thiazole
• 2-(N⁴-Phthalylsulfanilamido)thiazole
• 2-([4-[(1,3-Thiazol-2-yl)sulfamoyl]phenyl]carbamoyl)benzoic acid
• 2-[[4-(Methylsulfamoyl)Phenyl]Carbamoyl]Benzoic Acid
• 2-[[[4-[(2-Thiazolylamino)Sulfonyl]Phenyl]Amino]Carbonyl]Benzoic Acid
• 2-{[4-(1,3-Thiazol-2-Ylsulfamoyl)Phenyl]Carbamoyl}Benzoic Acid
• 4-(2-Thiazolylsulfamyl)phthalanilic acid
• 4′-(2-Thiazolylsulfamoyl)phthalanilic acid
• AFI-Ftalyl
• Benzoic acid, 2-[[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]carbonyl]-
• Cremothalidine
• Enteramida
• Entero-sulfina
• Entexidina
• Ftalazol
• Ftalil-Esteve
• Ftalil-Septol
• Ftalysept
• Intestiazol
• NSC 66454
• NSC 683525
• P-St
• PST
• Phtalazol
• Phthalanilic acid, 4′-(2-thiazolylsulfamoyl)-
• Phthalazol
• Phthalidin
• Phthalylnorsulfazole
• Phthalylsulfathiazole
• Phthalylsulfonazole
• Sulfacetil
• Sulfaphthalazole
• Sulfathalidine
• Sulftalyl
• Sulphaphthalyl
• Taleudron
• Talidine
• Taloudron
• Thalazole
• Thalinil
• Thalistanin
• Thalistatyl
• Thiazole
• Ultratiazol
• 2-(n(sup4)-phthalyaminobenzenesulfonamide)thiazole
• -phthalylsulfanilamido)thiazole
• 2-((4-[(1,3-Thiazol-2-ylamino)sulfonyl]anilino)carbonyl)benzoic acid
• 2-(N4-PHTHALYSULFANILAMIDO)THIAZOLE
• -phthalyaminobenzenesulfonamido)thiazole
• N4-PHTHALYLSULFATHIAZOLE
• 2-(N4-Phthalylaminobenzenesulfonamide)thiazole
• -phthalyaminobenzenesulfonamide)thiazole
• 2-(p-N-Phthalylsulfanilyl)aminothiazole
• 4
• 2-(n(sup4)-phthalylsulfanilamido)thiazole
• 2-[[[4-[(2-THIAZOLYLAMINO)SULFONYL]PHENYLAMINO]CARBONYL]BENZOIC ACID
• PHTHALYLSULPHATHIAZOLE
• 2-(n(sup4)-phthalyaminobenzenesulfonamido)thiazole
• PHTHALYLSULFATHIOZOLE
• 2-(N-PHTHALYLAMINOBENZENESULFONAMIDO)THIAZOLE

Phthalylsulfathiazole

CAS: 85-73-4

Formula: C₁₇H₁₃N₃O₅S₂

Purity: >95.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 403.43

Ref: 3B-T0703

PHTHALYLSULFATHIAZOLE CRS

CAS: 85-73-4

PHTHALYLSULFATHIAZOLE CRS

Formula: C₁₇H₁₃N₃O₅S₂

Molecular weight: 403.4322

Ref: 41-P1500000

Phthalylsulfathiazole

CAS: 85-73-4

Phthalylsulfathiazole (N4-Phthalylsulfathiazole) is a broad spectrum antimicrobial agent, used in the treatment of dysentery, colitis, and gastroenteritis.

Formula: C₁₇H₁₃N₃O₅S₂

Purity: 97.16%

Color and Shape: Solid

Molecular weight: 403.43

Ref: TM-T0512

Phthalylsulfathiazole

CAS: 85-73-4

Phthalylsulfathiazole

Purity: ≥95%

Molecular weight: 403.43g/mol

Ref: 54-BUP19208

2-((4-(N-(Thiazol-2-Yl)Sulfamoyl)Phenyl)Carbamoyl)Benzoic Acid

CAS: 85-73-4

2-((4-(N-(Thiazol-2-Yl)Sulfamoyl)Phenyl)Carbamoyl)Benzoic Acid

Purity: 99%

Molecular weight: 403.43g/mol

Ref: 54-OR1009618

N4-Phthalylsulfathiazole

CAS: 85-73-4

Formula: C₁₇H₁₃N₃O₅S₂

Color and Shape: Neat

Molecular weight: 403.43

Ref: 04-C16190550

Phthalylsulfathiazole

CAS: 85-73-4

Color and Shape: Neat

Ref: 86-MM1935.00

Phthalylsulfathiazole

CAS: 85-73-4

Formula: C₁₇H₁₃N₃O₅S₂

Molecular weight: 403.43

Ref: 4Z-S-111004

Phthalylsulfathiazole

Controlled Product

CAS: 85-73-4

Applications Phthalylsulfathiazole (cas# 85-73-4) is a useful research chemical.

Formula: C₁₇H₁₃N₃O₅S₂

Color and Shape: Neat

Molecular weight: 403.43

Ref: TR-P397503

Phthalylsulfathiazole

CAS: 85-73-4

Phthalylsulfathiazole is a metal chelate that has been used as an antimicrobial agent and for the treatment of choroidal neovascularization. It has shown to be effective against infectious diseases such as urinary tract infections, pyelonephritis, and septicemia. Phthalylsulfathiazole is also used for the treatment of calcium pantothenate deficiency, which may be caused by intestinal bacteria. The drug's mechanism of action is not fully understood but it has been shown to bind to the hydroxyl group on DNA polymerase and inhibit its activity. Phthalylsulfathiazole can be synthesized in two ways: 1) Reaction with sodium carbonate and sodium citrate: 2) Reaction with sodium salts and metal ions: The reaction mechanism begins with the addition of metal ions onto the sulfonium salt. This leads to displacement of one chloride ion from the sulfonium salt,

Formula: C₁₇H₁₃N₃O₅S₂

Purity: Min. 95%

Molecular weight: 403.43 g/mol

Ref: 3D-FP40968