CAS 86-99-7

7-chloroquinolin-4-ol

Description:

7-Chloroquinolin-4-ol, with the CAS number 86-99-7, is an organic compound that belongs to the class of quinoline derivatives. It features a chloro substituent at the 7-position and a hydroxyl group at the 4-position of the quinoline ring system. This compound is characterized by its pale yellow to brownish color and is typically solid at room temperature. It is known for its potential biological activities, including antimicrobial and antimalarial properties, making it of interest in medicinal chemistry. The presence of the hydroxyl group contributes to its solubility in polar solvents, while the chloro group can influence its reactivity and interaction with biological targets. 7-Chloroquinolin-4-ol can participate in various chemical reactions, including nucleophilic substitutions and complexation with metal ions. Its structural features allow it to serve as a scaffold for the development of new pharmaceuticals, particularly in the search for effective treatments against infectious diseases. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₉H₆ClNO

InChI: InChI=1S/C9H6ClNO/c10-6-1-2-7-8(5-6)11-4-3-9(7)12/h1-5H,(H,11,12)

InChI key: InChIKey=XMFXTXKSWIDMER-UHFFFAOYSA-N

SMILES: OC=1C2=C(C=C(Cl)C=C2)N=CC1

Synonyms:

• 4-Hydroxy-7-chloroquinoline
• 4-Quinolinol, 7-chloro-
• 7-Chloro-4-Quinolinol
• 7-Chloro-4-hydroxyquinoline
• 7-chloroquinolin-4(1H)-one
• NSC 38928
• 7-Chloroquinolin-4-ol

7-Chloroquinolin-4-ol

CAS: 86-99-7

Formula: C₉H₆ClNO

Purity: 97%

Color and Shape: Solid

Molecular weight: 179.6030

Ref: IN-DA003NEW

Piperaquine Impurity 7

CAS: 86-99-7

Formula: C₉H₆ClNO

Color and Shape: White To Off-White Solid

Molecular weight: 179.60

Ref: 4Z-P-229

7-Chloro-4-hydroxyquinoline

CAS: 86-99-7

7-Chloro-4-hydroxyquinoline

Purity: 98%

Molecular weight: 179.60304g/mol

Ref: 54-OR183477

Piperaquine Impurity D

CAS: 86-99-7

Formula: C₉H₆ClNO

Molecular weight: 179.61

Ref: ST-EA-CP-P19004

7-Chloroquinolin-4-ol

CAS: 86-99-7

Formula: C₉H₆ClNO

Purity: 95%

Color and Shape: Solid

Molecular weight: 179.6

Ref: 10-F239098

7-Chloro-4-hydroxyquinoline

CAS: 86-99-7

7-Chloro-4-hydroxyquinoline is a quinoline derivative that has been shown to be an effective anti-tuberculosis agent. It inhibits bacterial growth by binding to DNA and RNA, preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 7-Chloro-4-hydroxyquinoline also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Formula: C₉H₆ClNO

Purity: (Hplc) Min. 98%

Color and Shape: Powder

Molecular weight: 179.6 g/mol

Ref: 3D-FC40597

7-Chloroquinolin-4-ol

CAS: 86-99-7

7-Chloroquinolin-4-ol is a useful organic compound for research related to life sciences. The catalog number is T66240 and the CAS number is 86-99-7.

Formula: C₉H₆ClNO

Color and Shape: Solid

Molecular weight: 179.6

Ref: TM-T66240