CAS: 88899-55-2 - (5R)-2,4-dideoxy-1-C-{(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl}-4-methyl-5-(1-methylethyl)-alpha-D-threo-pentopyranose

Formula: C₃₅H₅₈O₉

InChI: InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3/b14-12+,20-13+,21-16+,29-17-/t22-,23+,24-,25-,26-,27+,28-,30-,31+,32+,33+,35+/m0/s1

InChI key: InChIKey=XDHNQDDQEHDUTM-JQWOJBOSSA-N

SMILES: O=C1OC(C(OC)C=CC=C(C)CC(C)C(O)C(C=C(C=C1OC)C)C)C(C)C(O)C(C)C2(O)OC(C(C)C)C(C)C(O)C2

Synonyms:

• (-)-Bafilomycin A₁
• (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one
• (5R)-2,4-Dideoxy-1-C-{(2S,3R,4S)-3-hydroxy-4-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl}-5-isopropyl-4-methyl-alpha-D-threo-pentopyranose
• Hygrolidin, 21-O-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-
• NSC 381866
• Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 8-hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-
• Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 8-hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-
• Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 8-hydroxy-16-[2-hydroxy-1-methyl-3-[tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyl-, [7R-[3Z,5E,7R*,8S*,9S*,11E,13E,15S*,16R*[1S*,2R*,3S*(2R*,4R*,5S*,6R*)]]]-
• Oxacyclohexadecane, hygrolidin deriv.
• alpha-D-threo-Pentopyranose, 2,4-dideoxy-1-C-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-4-methyl-5-C-(1-methylethyl)-, (5R)-
• tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-

Bafilomycin A1

CAS: 88899-55-2

Bafilomycin A1 is a specific potent inhibitor of vacuolar ATPases.It is used as an antibacterial, …

• Formula: C₃₅H₅₈O₉
• Color and Shape: White, Solid or film
• Molecular weight: 622.84

Bafilomycin A1, 0.1 mg/ml in DMSO, sterile-filtered

CAS: 88899-55-2

Bafilomycin A1 is a potent and selective inhibitor of V-ATPase (vacuolar-type H+ ATPase). The compound …

• Formula: C₃₅H₅₈O₉
• Color and Shape: Liquid, Pale yellow
• Molecular weight: 622.84

(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one

CAS: 88899-55-2

• Formula: C₃₅H₅₈O₉
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 622.8296

Bafilomycin A1

CAS: 88899-55-2

• Formula: C₃₅H₅₈O₉
• Purity: By hplc: >95% (Typical Value in Batch COA)
• Color and Shape: white lyophilizate solid
• Molecular weight: 622.83g/mol

Bafilomycin A1

CAS: 88899-55-2

Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) …

• Formula: C₃₅H₅₈O₉
• Purity: 95.87% - 99.14%
• Color and Shape: Solid
• Molecular weight: 622.83

Bafilomycin A1

CAS: 88899-55-2

• Formula: C₃₅H₅₈O₉
• Purity: ≥ 97.0%
• Color and Shape: White or off-white solid
• Molecular weight: 622.83

Bafilomycin A1

CAS: 88899-55-2

Stability Hygroscopic Applications Bafilomycin A1 is a specific inhibitor of vacuolar type H+-ATPase (V-ATPase) in …

• Formula: C₃₅H₅₈O₉
• Color and Shape: Neat
• Molecular weight: 622.83

Bafilomycin A1

CAS: 88899-55-2

Inhibitor of vacuolar-type proton pump

• Formula: C₃₅H₅₈O₉
• Purity: Min. 95 Area-%
• Color and Shape: White Powder
• Molecular weight: 622.83 g/mol