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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 5592 products of "Apoptosis"

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  • Y-27632 HCl hydrate

    CAS:
    <p>Y-27632 HCl hydrate is an orally effective, ATP-competitive ROCK1/ROCK2 inhibitor (Ki=220 nM/300 nM) that inhibits caspase-3 and suppresses stem cell apoptosis.</p>
    Formula:C14H25Cl2N3O2
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:338.27
  • R406

    CAS:
    <p>R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.</p>
    Formula:C22H23FN6O5·C6H6O3S
    Purity:97.67% - 98.82%
    Color and Shape:Solid
    Molecular weight:628.63
  • R406 free base

    CAS:
    <p>R406 free base (R406 (free base)) is a potent Syk inhibitor.</p>
    Formula:C22H23FN6O5
    Purity:97.64% - 99.11%
    Color and Shape:Solid
    Molecular weight:470.45
  • β-mangostin

    CAS:
    <p>β-Mangostin: a xanthone in Cratoxylum arborescens, fights bacteria, malaria, tuberculosis (MIC 6.25μg/mL), and cancer.</p>
    Formula:C25H28O6
    Purity:98.01% - 99.69%
    Color and Shape:Faintly Yellow Powder
    Molecular weight:424.49
  • Xevinapant

    CAS:
    <p>Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.</p>
    Formula:C32H43N5O4
    Purity:98% - 99.94%
    Color and Shape:Solid
    Molecular weight:561.71
  • Alisertib Sodium

    CAS:
    <p>Alisertib Sodium (MLN 8237 Sodium)is a selective Aurora A inhibitor that causes G2/M phase arrest and chromosomal misalignment, leading to tumour cell apoptosis.</p>
    Formula:C27H19ClFN4NaO4
    Purity:99.77%
    Color and Shape:Solid
    Molecular weight:540.91
  • (R)-(-)-Gossypol acetic acid

    CAS:
    <p>(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.</p>
    Formula:C30H30O8·C2H4O2
    Purity:98.88% - 99.5%
    Color and Shape:Solid
    Molecular weight:578.61
  • All-trans-retinal

    CAS:
    <p>All-trans-retinal (Vitamin A aldehyde) is a one of the major vitamin A metabolites in the retina.</p>
    Formula:C20H28O
    Purity:98.56% - 98.70%
    Color and Shape:Solid
    Molecular weight:284.44
  • Tiplaxtinin

    CAS:
    <p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>
    Formula:C24H16F3NO4
    Purity:99.16% - 99.93%
    Color and Shape:Solid
    Molecular weight:439.38
  • Pilaralisib analogue

    CAS:
    <p>Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.</p>
    Formula:C21H16N6O2S2
    Purity:99.3% - 99.72%
    Color and Shape:Solid
    Molecular weight:448.52
  • Tripterin

    CAS:
    <p>Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.</p>
    Formula:C29H38O4
    Purity:98.56% - 99.8%
    Color and Shape:Red Crystalline Powder
    Molecular weight:450.61
  • AT9283

    CAS:
    <p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>
    Formula:C19H23N7O2
    Purity:99.83% - 99.98%
    Color and Shape:Solid
    Molecular weight:381.43
  • Solasodine

    CAS:
    <p>Solasodine, a toxic alkaloid from Solanaceae, kills HeLa cervical cancer and U937 leukemia cells.</p>
    Formula:C27H43NO2
    Purity:99.64% - 99.94%
    Color and Shape:Solid
    Molecular weight:413.64
  • PTC-028

    CAS:
    <p>PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected.</p>
    Formula:C19H12F5N5
    Purity:97.61% - 98.12%
    Color and Shape:Solid
    Molecular weight:405.32
  • Tamibarotene

    CAS:
    <p>Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic</p>
    Formula:C22H25NO3
    Purity:98.55% - 99.73%
    Color and Shape:Crystalline Solid
    Molecular weight:351.44
  • MI-136

    CAS:
    <p>MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.</p>
    Formula:C23H21F3N6S
    Purity:98.63% - 99.12%
    Color and Shape:Solid
    Molecular weight:470.51
  • D-Pantothenic acid sodium

    CAS:
    <p>D-Pantothenic acid sodium, a sodium salt of D-pantothenate, is a vital B5 derivative, aiding fat, carb, and amino acid oxidation.</p>
    Formula:C9H16NNaO5
    Purity:97.98%
    Color and Shape:White Powder
    Molecular weight:241.22
  • Avadomide

    CAS:
    <p>Avadomide (CC 122) is an orally available pleiotropic pathway modulator with potential antineoplastic activity.</p>
    Formula:C14H14N4O3
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:286.29
  • HS-173

    CAS:
    <p>HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).</p>
    Formula:C21H18N4O4S
    Purity:99.33% - 99.64%
    Color and Shape:Solid
    Molecular weight:422.46
  • Tofacitinib

    CAS:
    <p>Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.</p>
    Formula:C16H20N6O
    Purity:99% - >99.99%
    Color and Shape:Solid
    Molecular weight:312.37