Mdm2

28 products on this category.

Product data	Purity	Price range	Estimated delivery
MX69 REF: TM-T3653CAS: 1005264-47-0	97.27%	66.00 € ~ 834.00 €	3 Feb 2022
Kevetrin hydrochloride REF: TM-T3184CAS: 66592-89-0	99.93%	67.00 € ~ 941.00 €	3 Feb 2022
NSC 207895 REF: TM-T6610CAS: 58131-57-0	98.0%	156.00 € ~ 2,024.00 €	3 Feb 2022
Tenovin-1 REF: TM-T1919CAS: 380315-80-0	99.44%	65.00 € ~ 215.00 €	3 Feb 2022
RITA REF: TM-T1798CAS: 213261-59-7	98.49%	63.00 € ~ 349.00 €	3 Feb 2022
RG7112 REF: TM-T6965CAS: 939981-39-2	99.90%	88.00 € ~ 806.00 €	3 Feb 2022
MI-1061 REF: TM-T12031CAS: 1410737-34-6	98.00%	To inquire	3 Feb 2022
SJ-172550 REF: TM-T16888CAS: 431979-47-4	98.00%	72.00 € ~ 729.00 €	3 Feb 2022
Nutlin-3a REF: TM-T6023CAS: 675576-98-4	95.62%	67.00 € ~ 382.00 €	3 Feb 2022
MI773 REF: TM-T6585CAS: 1303607-60-4	98.0%	66.00 € ~ 467.00 €	3 Feb 2022
MD-224 REF: TM-T11980CAS: 2136247-12-4	100.00%	85.00 € ~ 1,333.00 €	3 Feb 2022
BH3I1 REF: TM-T1493CAS: 300817-68-9	97.60%	59.00 € ~ 787.00 €	3 Feb 2022
Idasanutlin REF: TM-T6254CAS: 1229705-06-9	99.13%	41.00 € ~ 426.00 €	3 Feb 2022
YH239-EE REF: TM-T6149CAS: 1364488-67-4	100.00%	74.00 € ~ 695.00 €	3 Feb 2022
Nutlin-3b REF: TM-T6614CAS: 675576-97-3	98.83%	79.00 € ~ 384.00 €	3 Feb 2022
AM-8735 REF: TM-T14203CAS: 1429386-01-5	98.00%	To inquire	3 Feb 2022
PhiKan 083 REF: TM-T16523LCAS: 880813-36-5	98.20%	76.00 € ~ 236.00 €	3 Feb 2022
Siremadlin REF: TM-T5555CAS: 1448867-41-1	- - -	75.00 € ~ 1,024.00 €	3 Feb 2022
Nutlin3 REF: TM-T2158CAS: 548472-68-0	99.89%	77.00 € ~ 844.00 €	3 Feb 2022
SP 141 REF: TM-T21773CAS: 1253491-42-7	99.21%	94.00 € ~ 809.00 €	3 Feb 2022
AMG232 REF: TM-TQ0127CAS: 1352066-68-2	98.59%	111.00 € ~ 2,328.00 €	3 Feb 2022
MA242 REF: TM-T11931CAS: 1049704-18-8	98.00%	To inquire	3 Feb 2022
RO-5963 REF: TM-T16771CAS: 1416663-77-8	98.00%	To inquire	3 Feb 2022
MG-277 REF: TM-T12027	98.00%	To inquire	3 Feb 2022
Serdemetan REF: TM-T2243CAS: 881202-45-5	98.00%	72.00 € ~ 748.00 €	3 Feb 2022
RO8994 REF: TM-T3517CAS: 1309684-94-3	98.87%	72.00 € ~ 273.00 €	3 Feb 2022
Milademetan REF: TM-T12040CAS: 1398568-47-2	98.00%	174.00 € ~ 839.00 €	3 Feb 2022
PK11000 REF: TM-T4459CAS: 38275-34-2	100.00%	65.00 € ~ 376.00 €	3 Feb 2022

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MX69

CAS:1005264-47-0

MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.

Formula:

C₂₇H₂₆N₂O₄S

Purity:

97.27%

Color and Shape:

Solid

Molecular weight:

474.57

Ref: TM-T3653

Estimated delivery in United States, on Thursday 3 Feb 2022

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Kevetrin hydrochloride

CAS:66592-89-0

Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor protein p53, with …

Formula:

C₅H₁₀ClN₃S

Purity:

99.93%

Color and Shape:

solid

Molecular weight:

179.67

Ref: TM-T3184

Estimated delivery in United States, on Thursday 3 Feb 2022

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NSC 207895

CAS:58131-57-0

NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and …

Formula:

C₁₁H₁₃N₅O₄

Purity:

98.0%

Color and Shape:

solid

Molecular weight:

279.25

Ref: TM-T6610

Estimated delivery in United States, on Thursday 3 Feb 2022

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Tenovin-1

CAS:380315-80-0

Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which …

Formula:

C₂₀H₂₃N₃O₂S

Purity:

99.44%

Color and Shape:

solid

Molecular weight:

369.48

Ref: TM-T1919

Estimated delivery in United States, on Thursday 3 Feb 2022

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RITA

CAS:213261-59-7

RITA(NSC 652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. …

Formula:

C₁₄H₁₂O₃S₂

Purity:

98.49%

Color and Shape:

solid

Molecular weight:

292.37

Ref: TM-T1798

Estimated delivery in United States, on Thursday 3 Feb 2022

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RG7112

CAS:939981-39-2

RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.

Formula:

C₃₈H₄₈Cl₂N₄O₄S

Purity:

99.90%

Color and Shape:

solid

Molecular weight:

726.28

Ref: TM-T6965

Estimated delivery in United States, on Thursday 3 Feb 2022

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MI-1061

CAS:1410737-34-6

MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).

Formula:

C₃₀H₂₆Cl₂FN₃O₄

Purity:

98.00%

Color and Shape:

Solid

Molecular weight:

582.45

Ref: TM-T12031

Estimated delivery in United States, on Thursday 3 Feb 2022

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SJ-172550

CAS:431979-47-4

SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).

Formula:

C₂₂H₂₁ClN₂O₅

Purity:

98.00%

Color and Shape:

Solid

Molecular weight:

428.87

Ref: TM-T16888

Estimated delivery in United States, on Thursday 3 Feb 2022

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Nutlin-3a

CAS:675576-98-4

Nutlin-3a, the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein.

Formula:

C₃₀H₃₀Cl₂N₄O₄

Purity:

95.62%

Color and Shape:

solid

Molecular weight:

581.49

Ref: TM-T6023

Estimated delivery in United States, on Thursday 3 Feb 2022

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MI773

CAS:1303607-60-4

MI-773 (SAR405838) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.

Formula:

C₂₉H₃₄Cl₂FN₃O₃

Purity:

98.0%

Color and Shape:

solid

Molecular weight:

562.5

Ref: TM-T6585

Estimated delivery in United States, on Thursday 3 Feb 2022

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MD-224

CAS:2136247-12-4

MD-224 is a highly potent and efficacious MDM2 degrader based on the proteolysistargeting chimera (PROTAC) …

Formula:

C₄₈H₄₃Cl₂FN₆O₆

Purity:

100.00%

Color and Shape:

Solid

Molecular weight:

889.8

Ref: TM-T11980

Estimated delivery in United States, on Thursday 3 Feb 2022

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BH3I1

CAS:300817-68-9

BH3I-1 is a Bcl-2 antagonist.

Formula:

C₁₅H₁₄BrNO₃S₂

Purity:

97.60%

Color and Shape:

solid

Molecular weight:

400.31

Ref: TM-T1493

Estimated delivery in United States, on Thursday 3 Feb 2022

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Idasanutlin

CAS:1229705-06-9

Idasanutlin (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).

Formula:

C₃₁H₂₉Cl₂F₂N₃O₄

Purity:

99.13%

Color and Shape:

solid

Molecular weight:

616.48

Ref: TM-T6254

Estimated delivery in United States, on Thursday 3 Feb 2022

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YH239-EE

CAS:1364488-67-4

YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.

Formula:

C₂₅H₂₇Cl₂N₃O₄

Purity:

100.00%

Color and Shape:

solid

Molecular weight:

504.41

Ref: TM-T6149

Estimated delivery in United States, on Thursday 3 Feb 2022

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Nutlin-3b

CAS:675576-97-3

Nutlin-3b is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 μM), 150-fold less potent (+)-enantiomer of …

Formula:

C₃₀H₃₀Cl₂N₄O₄

Purity:

98.83%

Color and Shape:

solid

Molecular weight:

581.49

Ref: TM-T6614

Estimated delivery in United States, on Thursday 3 Feb 2022

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AM-8735

CAS:1429386-01-5

AM-8735 is an inhibitor of MDM2 ( IC50: 25 nM).

Formula:

C₂₇H₃₁Cl₂NO₆S

Purity:

98.00%

Color and Shape:

Solid

Molecular weight:

568.51

Ref: TM-T14203

Estimated delivery in United States, on Thursday 3 Feb 2022

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PhiKan 083

CAS:880813-36-5

PhiKan 083 is a carbazole derivative

Formula:

C₁₆H₁₈N₂

Purity:

98.20%

Color and Shape:

solid

Molecular weight:

238.33

Ref: TM-T16523L

Estimated delivery in United States, on Thursday 3 Feb 2022

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Siremadlin

CAS:1448867-41-1

Siremadlin is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.

Formula:

C₂₆H₂₄Cl₂N₆O₄

Molecular weight:

555.41

Ref: TM-T5555

Estimated delivery in United States, on Thursday 3 Feb 2022

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Nutlin3

CAS:548472-68-0

Nutlin-3 is an MDM2 antagonist. Nutlin-3 inhibits the MDM2-p53 interaction (IC50: 0.09 μM) and activates …

Formula:

C₃₀H₃₀Cl₂N₄O₄

Purity:

99.89%

Color and Shape:

solid

Molecular weight:

581.49

Ref: TM-T2158

Estimated delivery in United States, on Thursday 3 Feb 2022

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SP 141

CAS:1253491-42-7

SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.

Formula:

C₂₂H₁₆N₂O

Purity:

99.21%

Color and Shape:

solid

Molecular weight:

324.38

Ref: TM-T21773

Estimated delivery in United States, on Thursday 3 Feb 2022

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AMG232

CAS:1352066-68-2

AMG 232 is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 …

Formula:

C₂₈H₃₅Cl₂NO₅S

Purity:

98.59%

Molecular weight:

568.55

Ref: TM-TQ0127

Estimated delivery in United States, on Thursday 3 Feb 2022

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MA242

CAS:1049704-18-8

MA242 is a nuclear factor of activated T cells 1 (NFAT1) for Pancreatic Cancer Therapy …

Formula:

C₂₆H₂₁ClF₃N₃O₅S

Purity:

98.00%

Color and Shape:

Solid

Molecular weight:

579.98

Ref: TM-T11931

Estimated delivery in United States, on Thursday 3 Feb 2022

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RO-5963

CAS:1416663-77-8

RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, …

Formula:

C₂₄H₂₁ClF₂N₄O₅

Purity:

98.00%

Color and Shape:

Solid

Molecular weight:

518.9

Ref: TM-T16771

Estimated delivery in United States, on Thursday 3 Feb 2022

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MG-277

MG-277 is a molecular glue compound transformed from PROTAC degradation agent, MG-277 potently inhibits tumor …

Formula:

C₄₁H₄₂Cl₂FN₅O₅

Purity:

98.00%

Color and Shape:

solid

Molecular weight:

774.71

Ref: TM-T12027

Estimated delivery in United States, on Thursday 3 Feb 2022

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Serdemetan

CAS:881202-45-5

Serdemetan is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.

Formula:

C₂₁H₂₀N₄

Purity:

98.00%

Color and Shape:

solid

Molecular weight:

328.42

Ref: TM-T2243

Estimated delivery in United States, on Thursday 3 Feb 2022

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RO8994

CAS:1309684-94-3

RO8994 is a highly effective and specific inhibitor of spiroindolinone small-molecule MDM2, with IC50 of …

Formula:

C₃₁H₃₁Cl₂FN₄O₄

Purity:

98.87%

Color and Shape:

solid

Molecular weight:

613.51

Ref: TM-T3517

Estimated delivery in United States, on Thursday 3 Feb 2022

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Milademetan

CAS:1398568-47-2

Milademetan is a specific and oral inhibitor of MDM2.

Formula:

C₃₀H₃₄Cl₂FN₅O₄

Purity:

98.00%

Color and Shape:

Solid

Molecular weight:

618.53

Ref: TM-T12040

Estimated delivery in United States, on Thursday 3 Feb 2022

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PK11000

CAS:38275-34-2

PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.

Formula:

C₆H₅ClN₂O₄S

Purity:

100.00%

Color and Shape:

solid

Molecular weight:

236.63

Ref: TM-T4459

Estimated delivery in United States, on Thursday 3 Feb 2022

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