BCL
BCL inhibitors are compounds that target the BCL-2 family of proteins, which play a key role in the regulation of apoptosis. The BCL-2 family includes both pro-apoptotic and anti-apoptotic members that control the mitochondrial pathway of apoptosis. Inhibiting anti-apoptotic BCL-2 proteins can promote cell death in cancer cells, making BCL inhibitors crucial in cancer therapy research. At CymitQuimica, we provide a comprehensive selection of high-quality BCL inhibitors to support your research in cancer, apoptosis, and cell biology.
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Dehydrocorydaline
CAS:30045-16-0
1.
Formula:
C22H24NO4
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
366.43
Ref: TM-T5S2358
| 1mg | 56.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 257.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 549.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BAM7
CAS:331244-89-4
BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).
Formula:
C21H19N5O2S
Purity:
98.68% - 99.23%
Color and Shape:
Solid
Molecular weight:
405.47
Ref: TM-T2453
| 1mg | 38.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 204.00 € | ||
| 50mg | 371.00 € | ||
| 100mg | 557.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Kurarinone
CAS:34981-26-5
Kurarinone is a flavonoid extracted from the shrub Sophora flavescens, which has anti-tumor, estrogenic and …
Formula:
C26H30O6
Purity:
98% - 99.72%
Color and Shape:
Solid
Molecular weight:
438.51
Ref: TM-T5S0993
| 1mg | 46.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 424.00 € | ||
| 50mg | 612.00 € | ||
| 100mg | 855.00 € | ||
| 500mg | 1,705.00 € | ||
| 1mL*10mM (DMSO) | 144.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Obatoclax Mesylate
CAS:803712-79-0
Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with …
Formula:
C20H19N3O·CH4O3S
Purity:
99.67% - 99.88%
Color and Shape:
Solid
Molecular weight:
413.49
Ref: TM-T6275
| 5mg | 50.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 209.00 € | ||
| 100mg | 351.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
(E/Z)-TG003
CAS:300801-52-9
(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.
Formula:
C13H15NO2S
Purity:
98% - 99.04%
Color and Shape:
Solid
Molecular weight:
249.33
Ref: TM-T1901
| 1mg | 48.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 262.00 € | ||
| 50mg | 448.00 € | ||
| 100mg | 655.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BI-3802
CAS:2166387-65-9
BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, …
Formula:
C24H29ClN6O3
Purity:
98.58%
Color and Shape:
Solid
Molecular weight:
484.98
Ref: TM-T5408
| 1mg | 143.00 € | ||
| 5mg | 347.00 € | ||
| 10mg | 517.00 € | ||
| 25mg | 833.00 € | ||
| 50mg | 1,132.00 € | ||
| 100mg | 1,542.00 € | ||
| 1mL*10mM (DMSO) | 375.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
S63845
CAS:1799633-27-4
S63845 is a selective myeloid leukemia 1(MCL1) inhibitor that binds to human MCL1 with a …
Formula:
C39H37ClF4N6O6S
Purity:
97.7% - ≥98%
Color and Shape:
Solid
Molecular weight:
829.26
Ref: TM-T5346
| 1mg | 85.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 231.00 € | ||
| 25mg | 412.00 € | ||
| 50mg | 607.00 € | ||
| 1mL*10mM (DMSO) | 212.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Navitoclax
CAS:923564-51-6
View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein …
Formula:
C47H55ClF3N5O6S3
Purity:
100% - 99.67%
Color and Shape:
Pale Yellow Solid
Molecular weight:
974.61
Ref: TM-T2101
| 5mg | 48.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 143.00 € | ||
| 100mg | 184.00 € | ||
| 200mg | 316.00 € | ||
| 500mg | 716.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Desmorpholinyl Navitoclax-NH-Me
CAS:2365172-82-1
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN …
Formula:
C44H51ClF3N5O5S3
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
918.55
Ref: TM-T39910
| 1mg | 69.00 € | ||
| 2mg | 91.00 € | ||
| 5mg | 155.00 € | ||
| 10mg | 236.00 € | ||
| 25mg | 432.00 € | ||
| 50mg | 582.00 € | ||
| 100mg | 758.00 € | ||
| 200mg | 998.00 € | ||
| 1mL*10mM (DMSO) | 238.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Triacetylresveratrol
CAS:42206-94-0
Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic …
Formula:
C20H18O6
Purity:
99.81%
Color and Shape:
Off White Powder
Molecular weight:
354.35
Ref: TM-T5668
| 1g | 96.00 € | ||
| 500mg | 73.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Gossypol
CAS:303-45-7
Gossypol (BL 193) Acetate is a polyphenolic aldehyde that permeates cells and acts as an …
Formula:
C30H30O8
Purity:
98.52% - 99.89%
Color and Shape:
Solid
Molecular weight:
518.55
Ref: TM-T6518
| 10mg | 41.00 € | ||
| 25mg | 62.00 € | ||
| 50mg | 89.00 € | ||
| 100mg | 118.00 € | ||
| 500mg | 278.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
TC11
CAS:100823-03-8
TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of …
Formula:
C20H22N2O2
Purity:
97.86%
Color and Shape:
Solid
Molecular weight:
322.4
Ref: TM-T9083
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 308.00 € | ||
| 100mg | 466.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
(R)-(-)-Gossypol acetic acid
CAS:866541-93-7
(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. …
Formula:
C30H30O8·C2H4O2
Purity:
96.73% - 99.5%
Color and Shape:
Solid
Molecular weight:
578.61
Ref: TM-T6396
| 1g | 1,341.00 € | ||
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 279.00 € | ||
| 100mg | 458.00 € | ||
| 500mg | 994.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
S55746 hydrochloride
CAS:1448525-91-4
S55746 hydrochloride is a potent, orally active and selective inhibitor of BCL-2(Ki of 1.3 nM …
Formula:
C43H43ClN4O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
747.28
Ref: TM-T12824
| 25mg | 585.00 € | ||
| 50mg | 769.00 € | ||
| 100mg | 1,318.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
3',6-Disinapoylsucrose
CAS:139891-98-8
3',6-Disinapoylsucrose (Disinapoyl sucrose) shows the neuroprotective effect and antidepressive activity in rats.
Formula:
C34H42O19
Purity:
99.02% - ≥95%
Color and Shape:
Solid
Molecular weight:
754.69
Ref: TM-T3697
| 20mg | 116.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
17-Hydroxy sprengerinin C
CAS:1029017-75-1
17-Hydroxy sprengerinin C, a glycoside from Polygonatum sibiricum, has potent anticancer effects, modulating Blc-2, Bax, …
Formula:
C44H70O17
Purity:
96%
Color and Shape:
Solid
Molecular weight:
871.02
Ref: TM-TN1195
| 1mg | 95.00 € | ||
| 5mg | 213.00 € | ||
| 1mL*10mM (DMSO) | 331.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
HA14-1
CAS:65673-63-4
HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 …
Formula:
C17H17BrN2O5
Purity:
95.07% - 98%
Color and Shape:
Solid
Molecular weight:
409.23
Ref: TM-T1980
| 10mg | 46.00 € | ||
| 25mg | 67.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 124.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
ML311
CAS:315698-17-0
ML311 is a selective inhibitor of the Mcl-1/Bim interaction.
Formula:
C23H24F3N3O
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
415.45
Ref: TM-T5108
| 1mg | 43.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 234.00 € | ||
| 50mg | 420.00 € | ||
| 100mg | 616.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Gambogic Acid
CAS:2752-65-0
Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases.
Formula:
C38H44O8
Purity:
97.16% - 98.67%
Color and Shape:
Solid
Molecular weight:
628.75
Ref: TM-T6185
| 2mg | 39.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 157.00 € | ||
| 100mg | 222.00 € | ||
| 500mg | 545.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Venetoclax
CAS:1257044-40-8
Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders …
Formula:
C45H50ClN7O7S
Purity:
98% - 99.96%
Color and Shape:
Solid
Molecular weight:
868.44
Ref: TM-T2119
| 1g | 556.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 74.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 112.00 € | ||
| 500mg | 356.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
