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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3477 products of "Cell Cycle/Checkpoint"

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  • Haspin-IN-2

    CAS:
    <p>Haspin-IN-2 is a potent haspin inhibitor (IC50: 50 nM) and also inhibits CLK1 (IC50: 445 nM) and DYRK1A (IC50: 917 nM).</p>
    Formula:C12H8N4O3
    Color and Shape:Solid
    Molecular weight:256.22
  • Fradafiban

    CAS:
    <p>Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.</p>
    Formula:C20H21N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:367.40
  • 2'-F-UMP

    CAS:
    <p>2'-F-UMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Formula:C9H12FN2O8P
    Molecular weight:326.17
  • 6-B345TTQ

    CAS:
    <p>6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.</p>
    Formula:C22H20BrNO4
    Color and Shape:Solid
    Molecular weight:442.303
  • Galidesivir

    CAS:
    <p>Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.</p>
    Formula:C11H15N5O3
    Purity:96.73% - 99.13%
    Color and Shape:Solid
    Molecular weight:265.27
  • Des-ethyl-carafiban

    CAS:
    <p>Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.</p>
    Formula:C22H23N5O5
    Color and Shape:Solid
    Molecular weight:437.448
  • 2′-O-MOE-AMP

    CAS:
    <p>2′-O-MOE-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Formula:C13H20N5O8P
    Color and Shape:Solid
    Molecular weight:405.30
  • CDK4/6-IN-13

    CAS:
    <p>Compounds 10B and 10C: potent cdk4/6 inhibitors with low nM activity, great antiproliferative effects, excellent metabolism, and good pharmacokinetics.</p>
    Formula:C25H29N7O
    Color and Shape:Solid
    Molecular weight:443.54
  • Aurora B inhibitor 1

    CAS:
    <p>Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki &lt;0.010 uM) with potential anticancer activity for cancer research.</p>
    Formula:C25H26ClF2N7O2
    Purity:98.37%
    Color and Shape:Solid
    Molecular weight:529.97
  • PD-1/PD-L1-IN-53

    CAS:
    <p>PD-1/PD-L1-IN-53 (compound B3) serves as an inhibitor targeting both the PD-1/PD-L1 and VISTA signaling pathways. It is utilized in cancer research.</p>
    Formula:C31H37N3O4
    Color and Shape:Solid
    Molecular weight:515.64
  • 2'-F-AMP

    CAS:
    <p>2'-F-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Formula:C10H13FN5O6P
    Molecular weight:349.21
  • CDK2-IN-30

    CAS:
    <p>CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.</p>
    Formula:C18H25N7O3S
    Color and Shape:Solid
    Molecular weight:419.50
  • LNA-UTP

    CAS:
    <p>LNA-UTP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Formula:C10H15N2O15P3
    Color and Shape:Solid
    Molecular weight:496.15
  • BWC0977

    CAS:
    <p>BWC0977 is an effective topoisomerase inhibitor that disrupts bacterial DNA replication by targeting both DNA gyrase and topoisomerase IV. The minimum inhibitory concentration (MIC90) of BWC0977 against MDR (multi-drug resistant) Gram-negative bacteria ranges from 0.03 to 2 µg/mL.</p>
    Formula:C22H21FN6O5
    Color and Shape:Solid
    Molecular weight:468.44
  • DYRK1-IN-1

    CAS:
    <p>DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.</p>
    Formula:C12H12N6
    Color and Shape:Solid
    Molecular weight:240.26
  • GSK3-IN-10

    CAS:
    <p>GSK3-IN-10 (Compound 4) is a multi-target inhibitor primarily affecting GSK3α and GSK3β with IC50 values of 1.0 nM and 2.0 nM, respectively. It inhibits the activation of β-catenin, enhances neuronal survival, and provides protective effects against endoplasmic reticulum stress.</p>
    Formula:C17H18F2N4O3
    Color and Shape:Solid
    Molecular weight:364.347
  • Antitumor agent-74


    <p>Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.</p>
    Formula:C26H23FN6
    Color and Shape:Solid
    Molecular weight:438.5
  • Pseudouridine 5'-OTBDPS

    CAS:
    <p>Pseudouridine5'-OTBDPS [5-(5-O-TBDPS-β-D-ribofuranosyl)uracil] is an intermediate of Pseudouridine.</p>
    Formula:C25H30N2O6Si
    Color and Shape:Solid
    Molecular weight:482.60
  • N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine

    CAS:
    <p>N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a nucleoside analog that resembles the natural nucleotide adenosine in structure. It acts as an activator of ribonucleotide reductase, facilitating the conversion of ribonucleotides into deoxyribonucleotides.</p>
    Formula:C38H35N5O6
    Color and Shape:Solid
    Molecular weight:657.714
  • RNAP-σ interaction inhibitor-1

    CAS:
    <p>RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.</p>
    Formula:C19H11Cl3N2O6S2
    Color and Shape:Solid
    Molecular weight:533.79