Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(94 products)
- CDK(500 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(261 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(70 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
Show 10 more subcategories
Found 3477 products of "Cell Cycle/Checkpoint"
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PD 407824
CAS:<p>PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).</p>Formula:C20H12N2O3Purity:98.02%Color and Shape:SolidMolecular weight:328.322'-O-Methyl-5-iodouridine
CAS:<p>2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a</p>Formula:C10H13IN2O6Purity:99.89%Color and Shape:SolidMolecular weight:384.12TG003
CAS:<p>TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.</p>Formula:C13H15NO2SPurity:99.46%Color and Shape:SolidMolecular weight:249.33Talotrexin
CAS:<p>Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.</p>Formula:C27H27N9O6Color and Shape:SolidMolecular weight:573.56kb-NB77-78
CAS:<p>kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).</p>Formula:C18H25NO3SiPurity:99.54%Color and Shape:SolidMolecular weight:331.48Rabusertib
CAS:<p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>Formula:C18H22BrN5O3Purity:98.86% - 99.87%Color and Shape:SolidMolecular weight:436.3Trilaciclib
CAS:<p>Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.</p>Formula:C24H30N8OPurity:99.624%Color and Shape:SolidMolecular weight:446.55Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formula:C29H32N4O3SPurity:98.04% - 99.44%Color and Shape:SolidMolecular weight:516.65Mps1-IN-3 hydrochloride
<p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>Formula:C26H32ClN7O4SColor and Shape:SolidMolecular weight:574.09NSC 617145
CAS:<p>NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent</p>Formula:C13H10Cl4N2O4Purity:99.72%Color and Shape:SolidMolecular weight:400.04GDC0575 monohydrochloride
CAS:<p>GDC0575 (ARRY575), a potent Chk1 inhibitor, IC50 1.2nM, disrupts cell cycle arrest, allowing DNA repair before mitosis.</p>Formula:C16H21BrClN5OPurity:97.85%Color and Shape:SolidMolecular weight:414.73AT-9283 HCl
CAS:<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Formula:C19H24ClN7O2Color and Shape:SolidMolecular weight:417.89Dasabuvir sodium
CAS:<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Formula:C26H26N3NaO5SColor and Shape:SolidMolecular weight:515.56Phosphonoformic acid trisodium salt hexa
CAS:<p>Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.</p>Formula:CH12Na3O11PPurity:98%Color and Shape:SolidMolecular weight:300.03E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Formula:C17H12N4O2SPurity:98.31% - 99.11%Color and Shape:SolidMolecular weight:336.37EN4
CAS:<p>EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.</p>Formula:C25H24N2O4Purity:98.51%Color and Shape:SolidMolecular weight:416.47CKI-7 free base
CAS:<p>CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Formula:C11H12ClN3O2SColor and Shape:SolidMolecular weight:285.75MLS000532223
CAS:<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Formula:C15H9NO3Purity:98.6%Color and Shape:SolidMolecular weight:251.24TH-263
CAS:<p>TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.</p>Formula:C21H20N2O3SPurity:99.54%Color and Shape:SolidMolecular weight:380.46iRGD peptide
CAS:<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Formula:C35H57N13O14S2Purity:98.77%Color and Shape:SolidMolecular weight:948.04Orbofiban
CAS:<p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>Formula:C17H23N5O4Color and Shape:SolidMolecular weight:361.4APTO-253 HCl
CAS:<p>APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.</p>Formula:C22H15ClFN5Color and Shape:SolidMolecular weight:403.84HA-100 hydrochloride
CAS:<p>HA-100 hydrochloride inhibits protein kinases PKG, PKA, PKC, MLC-kinase (IC50: 4-240 μM) and ROCK.</p>Formula:C13H16ClN3O2SColor and Shape:SolidMolecular weight:313.8BMH-21
CAS:<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Formula:C21H20N4O2Purity:99.47% - 99.84%Color and Shape:SolidMolecular weight:360.41S-trityl-L-Cysteine
CAS:<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Formula:C22H21NO2SPurity:97.02%Color and Shape:Almost White To Light Yellow Granular PowderMolecular weight:363.47Apcin
CAS:<p>Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.</p>Formula:C13H14Cl3N7O4Purity:96.74%Color and Shape:SolidMolecular weight:438.65CHR-6494
CAS:<p>CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).</p>Formula:C16H16N6Purity:98.78%Color and Shape:SolidMolecular weight:292.34Palmatine chloride
CAS:<p>Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.</p>Formula:C21H22ClNO4Purity:97.9% - 99.47%Color and Shape:SolidMolecular weight:387.857Datelliptium chloride hydrochloride
CAS:<p>Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.</p>Formula:C23H29Cl2N3OPurity:99.46%Color and Shape:SolidMolecular weight:434.4CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Formula:C26H31BrN8OPurity:98.51% - 99.89%Color and Shape:SolidMolecular weight:551.48AZD-7762
CAS:<p>AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.</p>Formula:C17H19FN4O2SPurity:98.96% - 99.19%Color and Shape:SolidMolecular weight:362.42Netarsudil free base
CAS:<p>Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.</p>Formula:C28H27N3O3Color and Shape:SolidMolecular weight:453.53NG 52
CAS:<p>NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.</p>Formula:C16H19ClN6OPurity:98% - 99.34%Color and Shape:SolidMolecular weight:346.81LY3143921
CAS:<p>LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].</p>Formula:C16H12FN5OColor and Shape:SolidMolecular weight:309.3RCM-1
CAS:<p>RCM-1 is an inhibitor of FOXM1.</p>Formula:C20H12N2OS4Purity:98.08%Color and Shape:SolidMolecular weight:424.58IRE1α kinase-IN-1
CAS:<p>IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.</p>Formula:C26H26ClFN8Purity:99.18%Color and Shape:SolidMolecular weight:504.99Levomefolate calcium
CAS:<p>Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.</p>Formula:C20H23CaN7O6Purity:97.35%Color and Shape:Off-White To Pale Yellow SolidMolecular weight:497.52Carotegrast methyl
CAS:<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Formula:C28H26Cl2N4O5Purity:99.26% - 99.72%Color and Shape:SolidMolecular weight:569.44Brr2-IN-3
CAS:<p>Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.</p>Formula:C24H20N4O3SPurity:99.26%Color and Shape:SolidMolecular weight:444.51Avotaciclib trihydrochloride
CAS:<p>Avotaciclib trihydrochloride (BEY1107) is an oral CDK1 inhibitor targeting advanced pancreatic cancer.</p>Formula:C13H14Cl3N7OPurity:99%Color and Shape:SolidMolecular weight:390.653'-Deoxyguanosine
CAS:<p>3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.</p>Formula:C10H13N5O4Purity:98.85% - 98.96%Color and Shape:SolidMolecular weight:267.24Tempo
CAS:<p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>Formula:C9H18NOPurity:98.35%Color and Shape:Orange Crystals Or PowderMolecular weight:156.25AI-10-49
CAS:<p>AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.</p>Formula:C30H22F6N6O5Purity:97.14%Color and Shape:SolidMolecular weight:660.526-Thioinosine
CAS:<p>6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.</p>Formula:C10H12N4O4SPurity:97.74%Color and Shape:SolidMolecular weight:284.29Deoxythymidine triphosphate
CAS:<p>Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.</p>Formula:C10H14N2Na3O14P3Purity:99.78%Color and Shape:White Amorphous PowderMolecular weight:548.11PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:<p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>Formula:C18H21Cl3N4OPurity:99.5%Color and Shape:SolidMolecular weight:415.75Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Formula:C23H15F2NO2Purity:99.1% - 99.57%Color and Shape:SolidMolecular weight:375.37Pyridostatin hydrochloride
CAS:<p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>Formula:C31H37Cl5N8O5Color and Shape:SolidMolecular weight:778.94BMS-8
CAS:<p>BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.</p>Formula:C27H28BrNO3Purity:98.88%Color and Shape:SolidMolecular weight:494.42Mps1-IN-1 dihydrochloride
CAS:<p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>Formula:C28H35Cl2N5O4SColor and Shape:SolidMolecular weight:608.58UNC10217938A
CAS:<p>UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects.</p>Formula:C26H28N6O2Purity:98%Color and Shape:SolidMolecular weight:456.54LY3405105
CAS:<p>LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-</p>Formula:C26H39N7O3Purity:99.66%Color and Shape:SolidMolecular weight:497.63Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Formula:C26H30FN7O3Purity:98.43% - 99.29%Color and Shape:SolidMolecular weight:507.56N6,N6-Dimethyladenosine
CAS:<p>N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.</p>Formula:C12H17N5O4Purity:98.79%Color and Shape:White PowderMolecular weight:295.29Proguanil
CAS:<p>Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .</p>Formula:C11H16ClN5Purity:99.6%Color and Shape:SolidMolecular weight:253.73FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Formula:C17H18FN3SPurity:98.61%Color and Shape:SolidMolecular weight:315.41NVP-LCQ195
CAS:<p>NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).</p>Formula:C17H19Cl2N5O4SPurity:99.56% - 99.85%Color and Shape:SolidMolecular weight:460.33JSH-150
CAS:<p>JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).</p>Formula:C24H33ClN6O2SPurity:99.96% - 99.96%Color and Shape:SolidMolecular weight:505.08Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66Atuveciclib
CAS:<p>Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.</p>Formula:C18H18FN5O2SPurity:98.8%Color and Shape:SolidMolecular weight:387.432-Chloroadenosine
CAS:<p>2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively</p>Formula:C10H12ClN5O4Purity:99.23%Color and Shape:White PowderMolecular weight:301.69Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Formula:C29H29FN3O9PPurity:95.87%Color and Shape:SolidMolecular weight:613.53GSK461364
CAS:<p>GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.</p>Formula:C27H28F3N5O2SPurity:99% - 99.73%Color and Shape:SolidMolecular weight:543.6ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Formula:C30H30F3N5OPurity:99.30%Color and Shape:SolidMolecular weight:533.593-AP
CAS:<p>3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).</p>Formula:C7H9N5SPurity:97.33% - 99.87%Color and Shape:SolidMolecular weight:195.24CW-069
CAS:<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Formula:C23H21IN2O3Purity:97.52% - 99.52%Color and Shape:SolidMolecular weight:500.33CCG-203971
CAS:<p>CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.</p>Formula:C23H21ClN2O3Purity:98.82% - 99.50%Color and Shape:SolidMolecular weight:408.88SP-146
<p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>Formula:C25H20FN7OPurity:97.82%Color and Shape:SolidMolecular weight:453.47LY2880070
CAS:<p>LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.</p>Formula:C19H23N7O2Purity:99.77%Color and Shape:SolidMolecular weight:381.43BMS-1001
CAS:<p>BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).</p>Formula:C35H34N2O7Purity:98.43%Color and Shape:SolidMolecular weight:594.7WNK-IN-11
CAS:<p>WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)</p>Formula:C21H21Cl2N5OSPurity:98.32%Color and Shape:SolidMolecular weight:462.4Bractoppin
CAS:<p>Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits</p>Formula:C25H23FN4OPurity:98.38%Color and Shape:SolidMolecular weight:414.47DMT-2′Fluoro-dU Phosphoramidite
CAS:<p>DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.</p>Formula:C39H46FN4O8PPurity:99.5%Color and Shape:SolidMolecular weight:748.78BMS-5
CAS:<p>BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.</p>Formula:C17H14Cl2F2N4OSPurity:98.01% - 99.88%Color and Shape:SolidMolecular weight:431.292′-Deoxy-2′-fluoroguanosine
CAS:<p>2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).</p>Formula:C10H12FN5O4Purity:99.89%Color and Shape:SolidMolecular weight:285.23AZD-5597
CAS:<p>AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent</p>Formula:C23H28FN7OPurity:98.01%Color and Shape:SolidMolecular weight:437.51WR99210 hydrochloride(47326-86-3 free base)
CAS:<p>WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.</p>Formula:C14H19Cl4N5O2Purity:97.77% - 99.8%Color and Shape:SolidMolecular weight:431.14Saccharin 1-methylimidazole
CAS:<p>Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.</p>Formula:C7H5NO3S·C4H6N2Purity:98.21%Color and Shape:SolidMolecular weight:265.29LDC-4297 HCl (1453834-21-3(free base))
<p>LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.</p>Formula:C23H29ClN8OPurity:100%Color and Shape:SolidMolecular weight:469.02Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Formula:C30H33ClN4O2Purity:98% - 99.09%Color and Shape:SolidMolecular weight:517.06Bonafton
CAS:<p>Bonafton (Bonaphthone) is an antiviral agent.</p>Formula:C10H5BrO2Purity:97.16%Color and Shape:SolidMolecular weight:237.053-Deazauridine
CAS:<p>3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.</p>Formula:C10H13NO6Purity:99.86%Color and Shape:SolidMolecular weight:243.21Calcium N5-methyltetrahydrofolate
CAS:<p>Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and</p>Formula:C20H23CaN7O6Purity:99.41%Color and Shape:SolidMolecular weight:497.51CC-671
CAS:<p>CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.</p>Formula:C28H28N6O4Purity:98.66% - 98.8%Color and Shape:SolidMolecular weight:512.56Arg-Gly-Asp TFA (99896-85-2(free base))
<p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>Formula:C14H23F3N6O8Purity:99.2% - ≥98%Color and Shape:SolidMolecular weight:460.36Trifluridine/tipiracil hydrochloride mixture
CAS:<p>Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a</p>Formula:C29H34Cl2F6N8O12Purity:98% - 99.79%Color and Shape:SolidMolecular weight:871.53Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Formula:C20H18FNO4Purity:98.33% - 99.58%Color and Shape:SolidMolecular weight:355.36EHT 1864 2HCl
CAS:<p>EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.</p>Formula:C25H29Cl2F3N2O4SPurity:98.39% - 99.42%Color and Shape:SolidMolecular weight:581.47Danofloxacin
CAS:<p>Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.</p>Formula:C19H20FN3O3Purity:99.77% - 99.8%Color and Shape:SolidMolecular weight:357.38GPRP acetate (67869-62-9 free base)
CAS:<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Formula:C20H35N7O7Purity:>99.99%Color and Shape:SolidMolecular weight:485.536-O-Methyl Guanosine
CAS:<p>6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.</p>Formula:C11H15N5O5Purity:97.5%Color and Shape:SolidMolecular weight:297.27MLN0905
CAS:<p>MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).</p>Formula:C24H25F3N6SPurity:97.17% - 98%Color and Shape:SolidMolecular weight:486.56Levoleucovorin Calcium
CAS:<p>Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.</p>Formula:C20H21N7O7·CaPurity:99.07% - ≥98%Color and Shape:White Crystalline PowderMolecular weight:511.5BMS-3
CAS:<p>BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.</p>Formula:C17H12Cl2F2N4OSPurity:99.31% - 99.81%Color and Shape:SolidMolecular weight:429.27Fanotaprim
CAS:<p>Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.</p>Formula:C19H22N8OPurity:98.1%Color and Shape:SolidMolecular weight:378.43TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33EOAI3402143
CAS:<p>EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.</p>Formula:C25H28Cl2N4O3Purity:99.6%Color and Shape:SolidMolecular weight:503.42LY3177833
CAS:<p>LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)</p>Formula:C16H12FN5OPurity:99.87%Color and Shape:SolidMolecular weight:309.3LXW7
CAS:<p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>Formula:C29H48N12O12S2Purity:>99.99%Color and Shape:SolidMolecular weight:820.89AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43MSC2530818
CAS:<p>MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).</p>Formula:C18H17ClN4OPurity:98.93%Color and Shape:SolidMolecular weight:340.81GDC-0575
CAS:<p>GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).</p>Formula:C16H20BrN5OPurity:≥95%Color and Shape:SolidMolecular weight:378.27TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Formula:C31H31ClFN7O2Purity:98.49% - 99.62%Color and Shape:SolidMolecular weight:588.07HA-100
CAS:<p>HA-100 is an inhibitor of protein kinase</p>Formula:C13H15N3O2SPurity:99.44%Color and Shape:Pale Yellow Crystalline SolidMolecular weight:277.34Zoliflodacin
CAS:<p>Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.</p>Formula:C22H22FN5O7Purity:99.82% - 99.93%Color and Shape:SolidMolecular weight:487.44BS-181 dihydrochloride
CAS:<p>BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.</p>Formula:C22H34Cl2N6Color and Shape:SolidMolecular weight:453.46GNF2133 hydrochloride
CAS:<p>GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.</p>Formula:C24H31ClN6O2Color and Shape:SolidMolecular weight:471.06-Thio-2'-Deoxyguanosine
CAS:<p>6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.</p>Formula:C10H13N5O3SPurity:97.52%Color and Shape:SolidMolecular weight:283.31POL1-IN-1
CAS:<p>POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。</p>Formula:C21H20N6Purity:98% - 98.01%Color and Shape:SolidMolecular weight:356.42Ocifisertib(CFI-400945 free base)
CAS:<p>Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4.Cost-effective and quality-assured.</p>Formula:C33H34N4O3Purity:98.53% - 99.04%Color and Shape:SolidMolecular weight:534.65N1-Methylpseudouridine
CAS:<p>N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by</p>Formula:C10H14N2O6Purity:98.95% - 99.88%Color and Shape:SolidMolecular weight:258.23LJI308
CAS:<p>LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.</p>Formula:C21H18F2N2O2Purity:99.73% - 99.87%Color and Shape:SolidMolecular weight:368.38Acelarin
CAS:<p>Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.</p>Formula:C25H27F2N4O8PPurity:99.26%Color and Shape:SolidMolecular weight:580.47CYC-116
CAS:<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Formula:C18H20N6OSPurity:97.36% - 97.59%Color and Shape:SolidMolecular weight:368.46THZ1
CAS:<p>THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.</p>Formula:C31H28ClN7O2Purity:95.09% - 99.27%Color and Shape:SolidMolecular weight:566.05PFM01
CAS:<p>PFM01 inhibits MRE11 enzyme, steering DSBR towards NHEJ over HR.</p>Formula:C14H15NO2S2Purity:98.68%Color and Shape:SolidMolecular weight:293.4Simeprevir
CAS:<p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>Formula:C38H47N5O7S2Purity:99.45% - 99.92%Color and Shape:SolidMolecular weight:749.94Aurora kinase inhibitor-3
CAS:<p>Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,</p>Formula:C21H18F3N5OPurity:98.91%Color and Shape:SolidMolecular weight:413.4GW406108X(Z/E)
CAS:<p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>Formula:C20H11Cl2NO4Purity:98.23%Color and Shape:SolidMolecular weight:400.21Dalpiciclib
CAS:<p>Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.</p>Formula:C25H30N6O2Purity:99.69%Color and Shape:SolidMolecular weight:446.54MLN8054
CAS:<p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86A-205804
CAS:<p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>Formula:C15H12N2OS2Purity:98.07% - 98.52%Color and Shape:SolidMolecular weight:300.4TH588 hydrochloride
CAS:<p>TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.</p>Formula:C13H13Cl3N4Color and Shape:SolidMolecular weight:331.63Methotrexate metabolite
CAS:<p>DAMPA, active metabolite of Methotrexate, is a chemotherapeutic and immunosuppressive folic acid antagonist.</p>Formula:C15H15N7O2Purity:95.60% - 97.59%Color and Shape:SolidMolecular weight:325.33SBC-115337
CAS:<p>SBC-115337 is a PCSK9 inhibitor.</p>Formula:C29H19N3O4Purity:99.41%Color and Shape:SolidMolecular weight:473.48BTYNB
CAS:<p>BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.</p>Formula:C12H9BrN2OSPurity:≥95%Color and Shape:SolidMolecular weight:309.18Y16 acetate(429653-73-6 free base)
<p>Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA</p>Formula:C51H74N14O13Purity:98%Color and Shape:SolidMolecular weight:1091.24Briciclib
CAS:<p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>Formula:C19H23O10PSPurity:98% - 99.84%Color and Shape:SolidMolecular weight:474.42Nemorubicin
CAS:<p>Nemorubicin (PNU 152243) is a unique doxorubicin variant with varied antitumor action, metabolism, and toxicity, effective against resistant tumors.</p>Formula:C32H37NO13Purity:97.4%Color and Shape:SolidMolecular weight:643.64Amenamevir
CAS:<p>Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mL</p>Formula:C24H26N4O5SPurity:99.00% - 99.86%Color and Shape:SolidMolecular weight:482.55Garenoxacin mesylate hydrate
CAS:<p>Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains</p>Formula:C23H20F2N2O4·CH4O3S·H2OPurity:99.56%Color and Shape:SolidMolecular weight:540.53CCT245737
CAS:<p>CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.</p>Formula:C16H16F3N7OPurity:98.06% - 99.69%Color and Shape:SolidMolecular weight:379.34IMP-1088
CAS:<p>IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.</p>Formula:C25H29F2N5OPurity:98.48% - 99.52%Color and Shape:SolidMolecular weight:453.53TAK-960 monohydrochloride
CAS:<p>TAK-960 monohydrochloride, an oral compound, inhibits PLK1 (IC50=0.8 nM), PLK2, PLK3, stunts cancer cell growth, and is effective in tumor models.</p>Formula:C27H35ClF3N7O3Color and Shape:SolidMolecular weight:598.07Pritelivir
CAS:<p>Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).</p>Formula:C18H18N4O3S2Purity:97.96% - 99.42%Color and Shape:SolidMolecular weight:402.49Senexin A
CAS:<p>Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.</p>Formula:C17H14N4Purity:99.74%Color and Shape:SolidMolecular weight:274.32SEL120-34A HCl
CAS:<p>SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectively</p>Formula:C15H19Br2ClN4Purity:98.13% - 98.47%Color and Shape:SolidMolecular weight:450.6FEN1-IN-SC13
CAS:<p>FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)</p>Formula:C24H23N3O3SPurity:98.02%Color and Shape:SolidMolecular weight:433.52Palbociclib
CAS:<p>Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.</p>Formula:C24H29N7O2Purity:98% - 99.9%Color and Shape:SolidMolecular weight:447.53LY2334737
CAS:<p>LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.</p>Formula:C17H25F2N3O5Purity:98.82%Color and Shape:SolidMolecular weight:389.39MLS-573151
CAS:<p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Dalpiciclib hydrochloride
<p>Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.</p>Formula:C25H31ClN6O2Color and Shape:SolidMolecular weight:483.01SBC-110736
CAS:<p>SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor</p>Formula:C26H27N3O2Purity:99.44%Color and Shape:SolidMolecular weight:413.51DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:<p>DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.</p>Formula:C41H49N4O9PPurity:98.28%Color and Shape:SolidMolecular weight:772.82FOY 251
CAS:<p>FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.</p>Formula:C17H19N3O7SPurity:97.11% - 99.33%Color and Shape:SolidMolecular weight:409.415-BrdU
CAS:<p>5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!</p>Formula:C9H11BrN2O5Purity:99.54% - 99.87%Color and Shape:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:307.1TAK-960 hydrochloride
CAS:<p>TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.</p>Formula:C27H35ClF3N7O3Color and Shape:SolidMolecular weight:598.06BMS-1166
CAS:<p>BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.</p>Formula:C36H33ClN2O7Purity:99.22%Color and Shape:SolidMolecular weight:641.11SCH900776
CAS:<p>SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.</p>Formula:C15H18BrN7Purity:96.69% - 99.6%Color and Shape:SolidMolecular weight:376.25TH5427 hydrochloride
CAS:<p>TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.</p>Formula:C20H21Cl3N8O3Color and Shape:SolidMolecular weight:527.79Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Formula:C32H46O8Purity:97.1% - 99.33%Color and Shape:SolidMolecular weight:558.7Ibezapolstat
CAS:<p>Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.</p>Formula:C18H20Cl2N6O2Purity:98% - 99.429%Color and Shape:SolidMolecular weight:423.3RI-1
CAS:<p>RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).</p>Formula:C14H11Cl3N2O3Purity:99.3% - 99.62%Color and Shape:SolidMolecular weight:361.61Y16
CAS:<p>Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.</p>Formula:C24H20N2O3Purity:98.26% - 99.32%Color and Shape:SolidMolecular weight:384.43TMPyP4 tosylate
CAS:<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Formula:C72H66N8O12S4Purity:98.61% - 99.85%Color and Shape:SolidMolecular weight:1363.6RNase L-IN-2
CAS:<p>RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.</p>Formula:C16H14N2O2SPurity:98.81%Color and Shape:SolidMolecular weight:298.365'-Deoxy-5-fluorocytidine
CAS:<p>5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.</p>Formula:C9H12FN3O4Purity:99.67%Color and Shape:White SolidMolecular weight:245.21PNU112455A hydrochloride
CAS:<p>PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.</p>Formula:C10H12ClN5O2SPurity:98.58% - 99.22%Color and Shape:SolidMolecular weight:301.75Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Formula:C22H39ClN2O6SPurity:98.81% - >99.99%Color and Shape:White SolidMolecular weight:495.07STAMBP-IN-1
CAS:<p>STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after</p>Formula:C27H28N4O4SPurity:99.64%Color and Shape:SolidMolecular weight:504.62-Aminofluorene
CAS:<p>2-Aminofluorene (2-Fluorenamine) is a biochemical.</p>Formula:C13H11NPurity:99.9%Color and Shape:Light Yellow CrystallineMolecular weight:181.23ON-013100
CAS:<p>ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.</p>Formula:C19H22O7SPurity:98.27%Color and Shape:SolidMolecular weight:394.44Pyridostatin
CAS:<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Formula:C31H32N8O5Purity:98%Color and Shape:SolidMolecular weight:596.64Ribociclib succinate hydrate
CAS:<p>Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).</p>Formula:C27H38N8O6Purity:98%Color and Shape:SolidMolecular weight:570.65110074-G5
CAS:<p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>Formula:C18H12N4O3Purity:99.51% - 99.67%Color and Shape:SolidMolecular weight:332.31IMM-H007
CAS:<p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>Formula:C22H23N5O8Purity:97.73%Color and Shape:SolidMolecular weight:485.45Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34A-286982
CAS:<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Formula:C24H27N3O4SPurity:97.81%Color and Shape:SolidMolecular weight:453.55Adavosertib
CAS:<p>Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.</p>Formula:C27H32N8O2Purity:98.65% - 99.86%Color and Shape:SolidMolecular weight:500.6PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48ML216
CAS:<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Formula:C15H9F4N5OSPurity:98.12%Color and Shape:SolidMolecular weight:383.32Fadraciclib
CAS:<p>Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).</p>Formula:C21H31N7OPurity:99.75%Color and Shape:SolidMolecular weight:397.52Mitonafide
CAS:<p>Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.</p>Formula:C16H15N3O4Purity:99.89%Color and Shape:SolidMolecular weight:313.31CHR-6494 TFA
CAS:<p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>Formula:C18H17F3N6O2Purity:99.50%Color and Shape:SolidMolecular weight:406.36CAN508
CAS:<p>CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.</p>Formula:C9H10N6OPurity:98.65%Color and Shape:SolidMolecular weight:218.22CK7
CAS:<p>CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.</p>Formula:C14H12N6O2SPurity:99.54%Color and Shape:SolidMolecular weight:328.35HMN-214
CAS:<p>HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.</p>Formula:C22H20N2O5SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:424.47TAK-960
CAS:<p>TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.</p>Formula:C27H34F3N7O3Purity:97.06%Color and Shape:SolidMolecular weight:561.6Indisulam
CAS:<p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>Formula:C14H12ClN3O4S2Purity:98.68% - 99.77%Color and Shape:SolidMolecular weight:385.85Cyclo(-RGDfK) TFA
CAS:<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Formula:C29H42F3N9O9Purity:98.99% - 99.54%Color and Shape:SolidMolecular weight:717.69GSK2850163 hydrochloride
CAS:<p>GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.</p>Formula:C24H30Cl3N3OColor and Shape:SolidMolecular weight:482.87TAK-632
CAS:<p>TAK-632 is a potent pan-Raf inhibitor.</p>Formula:C27H18F4N4O3SPurity:98% - 99.5%Color and Shape:SolidMolecular weight:554.52SBC-115076
CAS:<p>SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.</p>Formula:C31H33N3O5Purity:97.07% - 99.89%Color and Shape:SolidMolecular weight:527.617BIO
CAS:<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Formula:C16H10BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:356.17Apcin-A
CAS:<p>Apcin-A is an anaphase-promoting complex (APC) inhibitor.</p>Formula:C10H14Cl3N5O2Color and Shape:SolidMolecular weight:342.61Roniciclib
CAS:<p>Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.</p>Formula:C18H21F3N4O3SPurity:98% - 98.63%Color and Shape:SolidMolecular weight:430.44GLPG0187
CAS:<p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>Formula:C29H37N7O5SPurity:99.4% - 99.70%Color and Shape:SolidMolecular weight:595.71Tiazofurin
CAS:<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Formula:C9H12N2O5SPurity:99.91%Color and Shape:SolidMolecular weight:260.272'-Deoxy-2'-fluorocytidine
CAS:<p>2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.</p>Formula:C9H12FN3O4Purity:99.90%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:245.21Cetraxate hydrochloride
CAS:<p>Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.</p>Formula:C17H24ClNO4Purity:99.75%Color and Shape:SolidMolecular weight:341.83PF-06873600
CAS:<p>PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.</p>Formula:C20H27F2N5O4SPurity:98.77% - 99.55%Color and Shape:SolidMolecular weight:471.52Hu7691
CAS:<p>Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.</p>Formula:C22H22ClF3N4OPurity:99.81%Color and Shape:SolidMolecular weight:450.88Risdiplam
CAS:<p>Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.</p>Formula:C22H23N7OPurity:98.68% - 99.64%Color and Shape:SolidMolecular weight:401.46Palmatine
CAS:<p>Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.</p>Formula:C21H22NO4Purity:96.28% - 99.49%Color and Shape:SolidMolecular weight:352.4AT7519 TFA
CAS:<p>AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.</p>Formula:C18H18Cl2F3N5O4Color and Shape:SolidMolecular weight:496.27Poloxin
CAS:<p>Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).</p>Formula:C18H19NO3Purity:99.19%Color and Shape:SolidMolecular weight:297.35Palbociclib dihydrochloride
<p>Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.</p>Formula:C24H31Cl2N7O2Color and Shape:SolidMolecular weight:520.45SPHINX
CAS:<p>SPHINX is a new generation inhibitor of SPRK1</p>Formula:C17H17F3N2O3Purity:99.29%Color and Shape:SolidMolecular weight:354.32Cdk5 Substrate acetate
<p>Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.</p>Formula:C55H103N15O14Purity:96.21%Color and Shape:SolidMolecular weight:1198.5AZD-5438
CAS:<p>AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).</p>Formula:C18H21N5O2SPurity:99.73% - 99.87%Color and Shape:SolidMolecular weight:371.46
