Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(94 products)
- CDK(500 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(261 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(70 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
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Found 3477 products of "Cell Cycle/Checkpoint"
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PHA-767491
CAS:<p>PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.</p>Formula:C12H11N3OPurity:99.49% - >99.99%Color and Shape:SolidMolecular weight:213.24Sarecycline free base
CAS:<p>Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.</p>Formula:C24H29N3O8Purity:98%Color and Shape:SolidMolecular weight:487.5Seliciclib
CAS:<p>Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.</p>Formula:C19H26N6OPurity:97.15% - 99.89%Color and Shape:White To Off-White SolidMolecular weight:354.45InhA-IN-2
CAS:<p>N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.</p>Formula:C16H15ClN2O2S2Purity:98.4%Color and Shape:SolidMolecular weight:366.89Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Formula:C13H9FN2SPurity:98.01%Color and Shape:SolidMolecular weight:244.29R-IMPP
CAS:<p>R-IMPP is an inhibitor of PCSK9 translation.</p>Formula:C24H27N3O2Purity:99.47% - 99.85%Color and Shape:SolidMolecular weight:389.496-Mercaptopurine hydrate
CAS:<p>6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.</p>Formula:C5H6N4OSPurity:97.54% - 99.14%Color and Shape:Light Yellow Crystalline PowderMolecular weight:170.19Mogroside I E1
CAS:<p>Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.</p>Formula:C36H62O9Purity:98.62% - 99.71%Color and Shape:SolidMolecular weight:638.87TH5487
CAS:<p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>Formula:C19H18BrIN4O2Purity:98.38% - 98.73%Color and Shape:SolidMolecular weight:541.18Ro3280
CAS:<p>Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).</p>Formula:C27H35F2N7O3Purity:97.1% - >99.99%Color and Shape:SolidMolecular weight:543.61360A
CAS:<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Formula:C27H23N5O2Purity:98.68%Color and Shape:SolidMolecular weight:449.5LIMK-IN-22j
CAS:<p>LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.</p>Formula:C20H21BrN8Purity:99.165%Color and Shape:SolidMolecular weight:453.34BI-847325
CAS:<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Formula:C29H28N4O2Purity:97.13% - 97.54%Color and Shape:SolidMolecular weight:464.56BS194
CAS:<p>BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.</p>Formula:C20H27N5O3Purity:99.85%Color and Shape:SolidMolecular weight:385.46CWHM-12
CAS:<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Formula:C26H32BrN5O6Purity:98.05% - 99.83%Color and Shape:SolidMolecular weight:590.47CRT0066854
CAS:<p>CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.</p>Formula:C24H25N5SColor and Shape:SolidMolecular weight:415.55CCG-222740
CAS:<p>CCG-222740 is an inhibitor of Rho/MRTF pathway</p>Formula:C23H19ClF2N2O3Purity:98.76%Color and Shape:SolidMolecular weight:444.86Ganciclovir sodium
CAS:<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formula:C9H13N5NaO4Purity:99.93%Color and Shape:SolidMolecular weight:278.22Aplidine
CAS:<p>Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM).</p>Formula:C57H87N7O15Purity:99.86%Color and Shape:SolidMolecular weight:1110.34Aurora kinase inhibitor-2
CAS:<p>Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).</p>Formula:C23H20N4O3Purity:98.66%Color and Shape:SolidMolecular weight:400.43Activated Protein C (390-404), human acetate
<p>Activated Protein C (390-404), human acetate (Activated Protein C ) inhibits APC anticoagulant activity.</p>Formula:C93H134N22O25Purity:99.92%Color and Shape:SolidMolecular weight:1960.19Clevudine
CAS:<p>Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.</p>Formula:C10H13FN2O5Purity:99.88% - 99.97%Color and Shape:SolidMolecular weight:260.22CID755673
CAS:<p>CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.</p>Formula:C12H11NO3Purity:97.68% - 99.84%Color and Shape:SolidMolecular weight:217.22MC180295
CAS:<p>MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.</p>Formula:C17H18N4O3SPurity:99.84%Color and Shape:SolidMolecular weight:358.41Favipiravir
CAS:<p>Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.</p>Formula:C5H4FN3O2Purity:97.32% - 99.90%Color and Shape:SolidMolecular weight:157.1Cyclo(-RGDfK)
CAS:<p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>Formula:C27H41N9O7Purity:95.29% - >99.99%Color and Shape:SolidMolecular weight:603.67AZ3146
CAS:<p>AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.</p>Formula:C24H32N6O3Purity:97.84% - >99.99%Color and Shape:SolidMolecular weight:452.55Metoprine
CAS:<p>Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.</p>Formula:C11H10Cl2N4Purity:98.42%Color and Shape:SolidMolecular weight:269.13CID44216842
CAS:<p>CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.</p>Formula:C22H20BrN3O3SPurity:99.66%Color and Shape:SolidMolecular weight:486.38SNS-314 Mesylate
CAS:<p>SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.</p>Formula:C18H15ClN6OS2·CH4O3SPurity:99.44% - 99.92%Color and Shape:SolidMolecular weight:527.04DHFR-IN-3
CAS:<p>DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.</p>Formula:C8H7BrN4Purity:99.521% - 99.65%Color and Shape:SolidMolecular weight:239.07NSAH
CAS:<p>NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-</p>Formula:C18H14N2O3Purity:99.27%Color and Shape:SolidMolecular weight:306.32M2N12
CAS:<p>M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.</p>Formula:C20H16ClN5O2Purity:98.01%Color and Shape:SolidMolecular weight:393.83HAMNO
CAS:<p>HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).</p>Formula:C17H13NO2Purity:99.96%Color and Shape:SolidMolecular weight:263.29TH287
CAS:<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Formula:C11H10Cl2N4Purity:97.73% - 99%Color and Shape:SolidMolecular weight:269.136-AZATHYMINE
CAS:<p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>Formula:C4H5N3O2Purity:99.47%Color and Shape:SolidMolecular weight:127.13-Methylcytidine
CAS:<p>3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.</p>Formula:C10H15N3O5Purity:99.52%Color and Shape:SolidMolecular weight:257.24IMT1B
CAS:<p>IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.</p>Formula:C24H21ClFNO6Purity:98.26% - 99.83%Color and Shape:SolidMolecular weight:473.88Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Formula:C18H16O8Purity:99.50% - 99.85%Color and Shape:SolidMolecular weight:360.31(1E)-CFI-400437 dihydrochloride
CAS:<p>(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.</p>Formula:C29H30Cl2N6O2Purity:97.08%Color and Shape:SolidMolecular weight:565.5Ganciclovir hydrate
CAS:<p>Ganciclovir hydrate: oral anti-cytomegalovirus; inhibits HSV 1/2, CMV, adenoviruses, FHV-1; brain-penetrating.</p>Formula:C9H15N5O5Color and Shape:SolidMolecular weight:273.249TH-257
CAS:<p>TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).</p>Formula:C24H26N2O3SPurity:98.23%Color and Shape:SolidMolecular weight:422.54SR18662
<p>SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.</p>Formula:C16H19Cl2N3O4SPurity:98.97% - 99.2%Color and Shape:SolidMolecular weight:420.31CRT0044876
CAS:<p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>Formula:C9H6N2O4Purity:98.27% - 98.98%Color and Shape:Brown PowderMolecular weight:206.15EHop-016
CAS:<p>EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.</p>Formula:C25H30N6OPurity:98.99% - >99.99%Color and Shape:SolidMolecular weight:430.555-Fluoroorotic acid
CAS:<p>5-Fluoroorotic acid is an inhibitor of thymidylate synthase.</p>Formula:C5H3FN2O4Purity:99.7% - >99.99%Color and Shape:White To Pale Yellow PowderMolecular weight:174.09RI-2
CAS:<p>RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.</p>Formula:C21H18Cl2N2O4Purity:99.63% - 99.86%Color and Shape:SolidMolecular weight:433.28Quarfloxin
CAS:<p>Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.</p>Formula:C35H33FN6O3Purity:99.77%Color and Shape:SolidMolecular weight:604.67AS2863619
CAS:<p>AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.</p>Formula:C16H14Cl2N8OPurity:>99.99%Color and Shape:SolidMolecular weight:405.242'-Fluoro-2'-Deoxyadenosine
CAS:<p>2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP).</p>Formula:C10H12FN5O3Purity:99.95%Color and Shape:SolidMolecular weight:269.23BRD9876
CAS:<p>BRD9876 is a selective inhibitor of MM1S growth.</p>Formula:C16H14N2Purity:97.81%Color and Shape:SolidMolecular weight:234.3Ro5-3335
CAS:<p>Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.</p>Formula:C13H10ClN3OPurity:99.42% - 99.87%Color and Shape:SolidMolecular weight:259.69XL228
CAS:<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Tozasertib
CAS:<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Formula:C23H28N8OSPurity:99.99%Color and Shape:SolidMolecular weight:464.59APY29
CAS:<p>APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.</p>Formula:C17H16N8Purity:96.51% - 98.46%Color and Shape:SolidMolecular weight:332.36SAR-020106
CAS:<p>SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.</p>Formula:C19H19ClN6OPurity:97.78%Color and Shape:SolidMolecular weight:382.85CID-797718
CAS:<p>CID-797718 is a protein kinase D1 (PKD1) inhibitor.</p>Formula:C12H11NO3Purity:98.91% - 99.21%Color and Shape:SolidMolecular weight:217.22Tipiracil hydrochloride
CAS:<p>Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).</p>Formula:C9H12Cl2N4O2Purity:98.13% - ≥95%Color and Shape:SolidMolecular weight:279.12Lurbinectedin
CAS:<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Formula:C41H44N4O10SPurity:98.11%Color and Shape:SolidMolecular weight:784.87THZ2
CAS:<p>THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).</p>Formula:C31H28ClN7O2Purity:98.28%Color and Shape:SolidMolecular weight:566.05Voruciclib
CAS:<p>Voruciclib: oral, selective CDK inhibitor (Ki: 0.626-9.1 nM), reduces MCL-1, targets CDK9 in diffuse large B-cell lymphoma.</p>Formula:C22H19ClF3NO5Purity:99.89%Color and Shape:SolidMolecular weight:469.84Pyrintegrin
CAS:<p>Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.</p>Formula:C23H25N5O3SPurity:99.19%Color and Shape:SolidMolecular weight:451.54GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Formula:C32H38ClN5O4Purity:96.22% - 98.02%Color and Shape:SolidMolecular weight:592.13P18IN011
CAS:<p>P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).</p>Formula:C15H12N2O5SPurity:97.63%Color and Shape:SolidMolecular weight:332.3310074-A4
CAS:<p>10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from</p>Formula:C18H14Cl2N2O3SPurity:99.06%Color and Shape:SolidMolecular weight:409.29Madrasin
CAS:<p>Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.</p>Formula:C16H17N5O2Purity:99.06% - 99.61%Color and Shape:SolidMolecular weight:311.34BCH001
CAS:<p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>Formula:C20H15F3N2O5Purity:99.06%Color and Shape:SolidMolecular weight:420.34Trimethoprim sulfate
CAS:<p>Trimethoprim sulfate, a dihydrofolate reductase inhibitor, treats bacterial infections and sometimes malaria; may depress hematopoiesis.</p>Formula:C28H38N8O10SColor and Shape:SolidMolecular weight:678.72Dimethylenastron
CAS:<p>Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.</p>Formula:C16H18N2O2SPurity:98.07%Color and Shape:SolidMolecular weight:302.39SCH900776 (S-isomer)
CAS:<p>SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).</p>Formula:C15H18BrN7Purity:99.88%Color and Shape:SolidMolecular weight:376.25THZ531
CAS:<p>THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).</p>Formula:C30H32ClN7O2Purity:97.17% - 99.86%Color and Shape:SolidMolecular weight:558.07Senexin B
CAS:<p>Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).</p>Formula:C27H26N6OPurity:99.67%Color and Shape:SolidMolecular weight:450.53RK33
CAS:<p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>Formula:C23H20N6O3Purity:99.04% - 99.72%Color and Shape:SolidMolecular weight:428.44WNK463
CAS:<p>WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).</p>Formula:C21H24F3N7O2Purity:>99.99% - ≥95%Color and Shape:SolidMolecular weight:463.46N2-Methylguanosine
CAS:<p>N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's</p>Formula:C11H15N5O5Purity:97.77%Color and Shape:SolidMolecular weight:297.27BIO-1211
CAS:<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Formula:C36H48N6O9Purity:99.33%Color and Shape:SolidMolecular weight:708.8Levofloxacin hydrochloride
CAS:<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formula:C18H21ClFN3O4Purity:99.78% - 99.98%Color and Shape:SolidMolecular weight:397.8dGTP
CAS:<p>dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and</p>Formula:C10H16N5O13P3Purity:99.64%Color and Shape:SolidMolecular weight:507.18Triazavirin
CAS:<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Formula:C5H7N6NaO5SPurity:99.55%Color and Shape:SolidMolecular weight:286.2T-5224
CAS:<p>T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription</p>Formula:C29H27NO8Purity:97.88% - 99.29%Color and Shape:SolidMolecular weight:517.53KIRA6
CAS:<p>KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.</p>Formula:C28H25F3N6OPurity:97.91%Color and Shape:SolidMolecular weight:518.53PRT4165
CAS:<p>PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor.</p>Formula:C15H9NO2Purity:98.91% - 99.6%Color and Shape:SolidMolecular weight:235.24BS-181 hydrochloride
CAS:<p>BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.</p>Formula:C22H32N6·HClPurity:99.21%Color and Shape:SolidMolecular weight:416.99CX-5461 dihydrochloride
<p>CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).</p>Formula:C27H29Cl2N7O2SColor and Shape:SolidMolecular weight:586.54Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Formula:C37H35F9N8O11Purity:97.09% - 99.84%Color and Shape:SolidMolecular weight:938.712,2'-Anhydrouridine
CAS:<p>2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.</p>Formula:C9H10N2O5Purity:98.45%Color and Shape:SolidMolecular weight:226.19Leukadherin-1
CAS:<p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>Formula:C22H15NO4S2Purity:98.49% - 98.93%Color and Shape:SolidMolecular weight:421.49GSK180736A
CAS:<p>GSK180736A: GRK2 inhibitor (IC50 0.77µM), >100x selectivity vs GRKs, weak at PKA (IC50 30µM), strong vs ROCK1 (IC50 100nM).</p>Formula:C19H16FN5O2Purity:98.38% - 98.98%Color and Shape:SolidMolecular weight:365.36Gadodiamide
CAS:<p>Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.</p>Formula:C16H26GdN5O8Purity:99.86%Color and Shape:SolidMolecular weight:573.66K858 (Racemic)
CAS:<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Formula:C13H15N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:277.345-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE
CAS:<p>5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.</p>Formula:C8H13N3SPurity:99.03%Color and Shape:SolidMolecular weight:183.27Folinic acid calcium hydrate
CAS:<p>Folinic acid (Leucovorin) calcium hydrate is a biofolic acid often used as a rescue agent with methotrexate (MTX) to reduce MTX-induced toxicity.</p>Formula:C20H23CaN7O8Color and Shape:SolidMolecular weight:529.523Sovilnesib
CAS:<p>Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.</p>Formula:C26H34F2N6O4SPurity:99.57%Color and Shape:SolidMolecular weight:564.65GJ103 sodium salt
CAS:<p>GJ103 sodium salt, a GJ072 analog, lowers surface tension, viscosity, and pH in aqueous solutions, aiding molecular movement.</p>Formula:C16H13N4NaO3SPurity:99.70% - 99.91%Color and Shape:SolidMolecular weight:364.36TAK-960 dihydrochloride
<p>TAK-960 dihydrochloride: oral PLK1 inhibitor, IC50 0.8 nM; also Hinders PLK2 and PLK3 (IC50s 16.9/50.2 nM); curbs cancer cell growth.</p>Formula:C27H36Cl2F3N7O3Color and Shape:SolidMolecular weight:634.52Spermine tetrahydrochloride
CAS:<p>Spermine tetrahydrochloride, a polyamine in all eukaryotic cells, protects DNA from free radicals.</p>Formula:C10H26N4·4HClPurity:99.75% - 99.82%Color and Shape:SolidMolecular weight:348.189-Ethylguanine
CAS:<p>9-Ethylguanine is a model nucleobase commonly used in the studies of DNA interactions with organometallic complexes.</p>Formula:C7H9N5OPurity:98.6%Color and Shape:SolidMolecular weight:179.18RAD51-IN-1
CAS:<p>Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.</p>Formula:C22H16ClN3OPurity:99.95%Color and Shape:SolidMolecular weight:373.83CBFβ Inhibitor
CAS:<p>CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.</p>Formula:C12H14N2OSPurity:96.50%Color and Shape:SolidMolecular weight:234.32NITD-2
CAS:<p>NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.</p>Formula:C23H19N3O4SPurity:98.03% - 99.46%Color and Shape:SolidMolecular weight:433.48Abemaciclib methanesulfonate
CAS:<p>Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).</p>Formula:C27H32F2N8·CH4O3SPurity:98.69% - 99.44%Color and Shape:SolidMolecular weight:602.7BUR1
CAS:<p>BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.</p>Formula:C16H17N5Purity:90%Color and Shape:SolidMolecular weight:279.34NSC23005 Sodium
CAS:<p>NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.</p>Formula:C13H16NNaO4SPurity:99.64%Color and Shape:SolidMolecular weight:305.32Monastrol
CAS:<p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>Formula:C14H16N2O3SPurity:98.02% - 98.59%Color and Shape:SolidMolecular weight:292.35AUZ 454
CAS:<p>AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.</p>Formula:C24H26F3N7O2Purity:99.59%Color and Shape:SolidMolecular weight:501.5CX-5461
CAS:<p>CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.</p>Formula:C27H27N7O2SPurity:95.44% - 99.25%Color and Shape:SolidMolecular weight:513.61Pipobroman
CAS:<p>Pipobroman (Vercyte) is an alkylating anti-cancer drug effective in PV and ET with low toxicity and thrombosis risk.</p>Formula:C10H16Br2N2O2Purity:97.08%Color and Shape:SolidMolecular weight:356.05BVDV-IN-1
CAS:<p>BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.</p>Formula:C20H22N4OPurity:98.43%Color and Shape:SolidMolecular weight:334.41PND-1186
CAS:<p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>Formula:C25H26F3N5O3Purity:99.14% - 99.75%Color and Shape:SolidMolecular weight:501.52-Amino-4-hydroxypyrrolo[2,3- d]pyrimidi
CAS:<p>2-Amino-4-hydroxypyrrolo[2,3-d]pyrimidine serves as an intermediate.</p>Formula:C6H6N4OPurity:99.21% - 99.42%Color and Shape:SolidMolecular weight:150.14Myoseverin
CAS:<p>Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.</p>Formula:C24H28N6O2Purity:99.25%Color and Shape:SolidMolecular weight:432.52OSU-T315
CAS:<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Formula:C30H30F3N5OPurity:98.69%Color and Shape:SolidMolecular weight:533.59HMN-176
CAS:<p>HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).</p>Formula:C20H18N2O4SPurity:98.92% - 98.99%Color and Shape:SolidMolecular weight:382.43PTC-209
CAS:<p>PTC-209 is a potent and selective BMI-1 inhibitor.</p>Formula:C17H13Br2N5OSPurity:99.43% - 99.887%Color and Shape:SolidMolecular weight:495.19Antitumor agent-152
CAS:<p>Organic compound, potential dCK inhibitor, with 2-ethyl-3-methoxyphenyl-1,3-thiazole and pyrimidine units.</p>Formula:C17H19N5O2S2Purity:95.00%Color and Shape:SolidMolecular weight:389.5TC-E 5003
CAS:<p>TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.</p>Formula:C16H14Cl2N2O4SPurity:97.01%Color and Shape:SolidMolecular weight:401.26PHA-680632
CAS:<p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>Formula:C28H35N7O2Purity:98.2%Color and Shape:SolidMolecular weight:501.62MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Formula:C20H19ClFN5OSPurity:99.09% - 99.79%Color and Shape:SolidMolecular weight:431.91Purvalanol B
CAS:<p>Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)</p>Formula:C20H25ClN6O3Purity:98.95%Color and Shape:SolidMolecular weight:432.9C/EBPα inducer 1
CAS:<p>C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via</p>Formula:C20H12FN3O4Purity:98.99%Color and Shape:SolidMolecular weight:377.33VPC-80051 racemate
CAS:<p>VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.</p>Formula:C16H13F2N3OPurity:97.36%Color and Shape:SolidMolecular weight:301.29HALOFUGINONE LACTATE
CAS:<p>HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.</p>Formula:C19H23BrClN3O6Purity:99.70% - 99.96%Color and Shape:SolidMolecular weight:504.8WEE1-IN-3
CAS:<p>WEE1-IN-3 (JUN76288) is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. It treatment of cancer and other proliferative diseases.</p>Formula:C28H31N7O2Purity:98.33%Color and Shape:SolidMolecular weight:497.59CB-6644
CAS:<p>CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.</p>Formula:C29H34ClFN4O5Purity:96.33% - 99.85%Color and Shape:SolidMolecular weight:573.062-Chloropyrazine
CAS:<p>2-Chloropyrazine is used in chemical industry.</p>Formula:C4H3ClN2Purity:98.98% - 99.89%Color and Shape:Clear Colorless To Yellowish LiquidMolecular weight:114.53ARQ 621
CAS:<p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>Formula:C28H24Cl2FN5O2Purity:97.01% - 98.38%Color and Shape:SolidMolecular weight:552.43Bredinin aglycone
CAS:<p>Bredinin aglycone (SM-108) is a purine nucleotide analog.</p>Formula:C4H5N3O2Purity:99.06%Color and Shape:SolidMolecular weight:127.1Palbociclib monohydrochloride
CAS:<p>Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases</p>Formula:C24H29N7O2·HClPurity:99.73% - >99.99%Color and Shape:SolidMolecular weight:483.99Nolatrexed
CAS:<p>Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.</p>Formula:C14H12N4OSPurity:97.53%Color and Shape:SolidMolecular weight:284.34Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
<p>Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation</p>Formula:C76H121N19O25SPurity:98.96%Color and Shape:SolidMolecular weight:1732.95Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Formula:C35H49N11O9S2·xC2H4O2Purity:99.7% - 99.87%Color and Shape:SolidMolecular weight:831.96 (free base)roxifiban
CAS:<p>Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.</p>Formula:C21H29N5O6Purity:98%Color and Shape:SolidMolecular weight:447.48PTC-209 hydrobromide
CAS:<p>PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in</p>Formula:C17H13Br2N5OS·HBrPurity:99.91%Color and Shape:SolidMolecular weight:576.1CVT-313
CAS:<p>CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.</p>Formula:C20H28N6O3Purity:97.46% - 97.97%Color and Shape:SolidMolecular weight:400.47YKL-5-124
CAS:<p>YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays</p>Formula:C28H33N7O3Purity:99.36%Color and Shape:SolidMolecular weight:515.61GW779439X
CAS:<p>GW779439X is an inhibitor of CDK.</p>Formula:C22H21F3N8Purity:97.87%Color and Shape:SolidMolecular weight:454.45KB-0742 dihydrochloride
CAS:<p>KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.</p>Formula:C16H27Cl2N5Purity:99.79%Color and Shape:SolidMolecular weight:360.33Besifloxacin Hydrochloride
CAS:<p>Besifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.</p>Formula:C19H21ClFN3O3·HClPurity:99.20%Color and Shape:Pale Yellow SolidMolecular weight:430.3TH588
CAS:<p>TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.</p>Formula:C13H12Cl2N4Purity:96.05% - 99.82%Color and Shape:SolidMolecular weight:295.17LP-935509
CAS:<p>LP-935509 is a selective, brain-permeable, small molecule competitive inhibitor of articulin-2-associated kinase 1 (AAK1).Cost-effective and quality-assured.</p>Formula:C20H24N6O3Purity:98.78% - 99.64%Color and Shape:SolidMolecular weight:396.44Raltitrexed
CAS:<p>Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.</p>Formula:C21H22N4O6SPurity:98.99% - 99.29%Color and Shape:Yellow Crystalline PowderMolecular weight:458.49AMG 900
CAS:<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Formula:C28H21N7OSPurity:98.4% - 99.51%Color and Shape:SolidMolecular weight:503.58MKC3946
CAS:<p>MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.</p>Formula:C21H20N2O3SPurity:99.65%Color and Shape:SolidMolecular weight:380.462′-O-Methylcytidine
CAS:<p>2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.</p>Formula:C10H15N3O5Purity:99.72%Color and Shape:SolidMolecular weight:257.24Palbociclib Isethionate
CAS:<p>Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。</p>Formula:C24H29N7O2·C2H6O4SPurity:99.01% - 99.27%Color and Shape:SolidMolecular weight:573.66Arginine-glycine-aspartic acid
CAS:<p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>Formula:C12H22N6O6Purity:99.11%Color and Shape:SolidMolecular weight:346.34Natalizumab
CAS:<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Purity:98.00%Color and Shape:LiquidMolecular weight:N/AFUBP1-IN-1
CAS:<p>FUBP1-in-1: Potent FUBP1 inhibitor with 11.0 M IC50, disrupts FUBP1-DNA binding.</p>Formula:C19H14F3N3O2SPurity:99.7%Color and Shape:SolidMolecular weight:405.39BMS-265246
CAS:<p>BMS-265246 is a potent and selective CDK1/2 inhibitor.</p>Formula:C18H17F2N3O2Purity:99.25% - 99.57%Color and Shape:SolidMolecular weight:345.34ML264
CAS:<p>ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.</p>Formula:C17H21ClN2O4SPurity:99.33% - 99.45%Color and Shape:SolidMolecular weight:384.88XMD8-92
CAS:<p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>Formula:C26H30N6O3Purity:98.21%Color and Shape:SolidMolecular weight:474.55Verosudil hydrochloride
CAS:<p>Verosudil (AR-12286) is a selective Rho kinase inhibitor, reducing IOP in XFS & OHT/XFG, offering a new treatment option.</p>Formula:C17H18ClN3O2SColor and Shape:SolidMolecular weight:363.86CCT241736
CAS:<p>CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3</p>Formula:C22H23Cl2N7Purity:96.2% - 99.81%Color and Shape:SolidMolecular weight:456.37NY2267
CAS:<p>NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl</p>Formula:C38H43N3O6Purity:99.16% - 99.27%Color and Shape:SolidMolecular weight:637.7610058-F4
CAS:<p>10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.</p>Formula:C12H11NOS2Purity:98% - 99.87%Color and Shape:SolidMolecular weight:249.35BTB-1
CAS:<p>BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.</p>Formula:C12H8ClNO4SPurity:99.71%Color and Shape:SolidMolecular weight:297.71Alisertib
CAS:<p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.</p>Formula:C27H20ClFN4O4Purity:98.31% - >99.99%Color and Shape:SolidMolecular weight:518.92SNS-314
CAS:<p>SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.</p>Formula:C18H15ClN6OS2Purity:98%Color and Shape:SolidMolecular weight:430.93LDN-192960 hydrochloride
CAS:<p>LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.</p>Formula:C18H22Cl2N2O2SPurity:98%Color and Shape:SolidMolecular weight:401.35Abemaciclib
CAS:<p>Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.</p>Formula:C27H32F2N8Purity:99.43% - 99.87%Color and Shape:SolidMolecular weight:506.59Silver sulfadiazine
CAS:<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Formula:C10H9AgN4O2SPurity:99.04% - 99.58%Color and Shape:SolidMolecular weight:357.14Camostat mesylate
CAS:<p>Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.</p>Formula:C21H26N4O8SPurity:99.31% - 99.85%Color and Shape:Crystalline SolidMolecular weight:494.52Tipiracil
CAS:<p>Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.</p>Formula:C9H11ClN4O2Purity:99.815%Color and Shape:SolidMolecular weight:242.66H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Formula:C23H38N10O10Purity:>99.99%Color and Shape:SolidMolecular weight:614.61Adefovir dipivoxil
CAS:<p>Adefovir dipivoxil (GS 0840) is a dipivoxil formulation of adefovir, a nucleoside reverse transcriptase inhibitor analog of adenosine with activity against</p>Formula:C20H32N5O8PPurity:98% - 99.80%Color and Shape:It Has Broad-Spectrum Antiviral ActivityMolecular weight:501.47Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.545-Fluorocytidine
CAS:<p>5-Fluorocytidine with antiviral activity</p>Formula:C9H12FN3O5Purity:99.23%Color and Shape:White PowderMolecular weight:261.21JNJ-7706621
CAS:<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Formula:C15H12F2N6O3SPurity:99.1% - 99.85%Color and Shape:SolidMolecular weight:394.36KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Formula:C20H20N4OPurity:98.43% - 99.69%Color and Shape:SolidMolecular weight:332.46-Bromo-2-hydroxy-3-methoxybenzaldehyde
CAS:<p>6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α (IC50 : 0.08 μM).</p>Formula:C8H7BrO3Purity:99.82%Color and Shape:SolidMolecular weight:231.04Ara-G
CAS:<p>Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.</p>Formula:C10H13N5O5Purity:98.74%Color and Shape:Slightly Off White To White PowderMolecular weight:283.24Empesertib
CAS:<p>Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.</p>Formula:C29H26FN5O4SPurity:97.45% - 99.4%Color and Shape:SolidMolecular weight:559.61Longdaysin
CAS:<p>Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).</p>Formula:C16H16F3N5Purity:99.97%Color and Shape:SolidMolecular weight:335.33Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.55CCG-100602
CAS:<p>CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).</p>Formula:C21H17ClF6N2O2Purity:99.58%Color and Shape:SolidMolecular weight:478.824μ8C
CAS:<p>4μ8C (IRE1 Inhibitor III)(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.</p>Formula:C11H8O4Purity:97.48% - 98.45%Color and Shape:SolidMolecular weight:204.18Didox
CAS:<p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>Formula:C7H7NO4Purity:99.83%Color and Shape:SolidMolecular weight:169.13T56-LIMKi
CAS:<p>T56-LIMKi (T5601640) is a selective inhibitor of LIMK2.</p>Formula:C19H14F3N3O3Purity:98.39% - 99.57%Color and Shape:SolidMolecular weight:389.33BAY-1816032
CAS:<p>BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor.Cost-effective and quality-assured.</p>Formula:C27H24F2N6O4Purity:98.02% - 99.81%Color and Shape:SolidMolecular weight:534.51Mycro 3
CAS:<p>Mycro 3 is potent and selective for c-Myc in whole cell assays.</p>Formula:C24H17ClF2N6O4Purity:99.51% - 99.61%Color and Shape:SolidMolecular weight:526.88ZCL278
CAS:<p>ZCL278 is a selective Cdc42 GTPase inhibitor.</p>Formula:C21H19BrClN5O4S2Purity:96.29% - 99.72%Color and Shape:SolidMolecular weight:584.89BRD32048
CAS:<p>BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.</p>Formula:C16H22N6OPurity:99.87%Color and Shape:SolidMolecular weight:314.39Tirapazamine
CAS:<p>Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.</p>Formula:C7H6N4O2Purity:96.65% - 99.87%Color and Shape:Orange-Red Crystalline PowderMolecular weight:178.15GAK inhibitor 49 hydrochloride
<p>Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.</p>Formula:C20H23ClN2O5Color and Shape:SolidMolecular weight:406.86PfDHODH-IN-1
CAS:<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Formula:C14H11F3N2O2Purity:99.87%Color and Shape:SolidMolecular weight:296.24TP-353
CAS:<p>TP-353 (EOS-61973) is a CDK7 inhibitor.</p>Formula:C35H30FNO3Purity:99.12%Color and Shape:SolidMolecular weight:531.62ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formula:C21H25N7Purity:97.63% - ≥95%Color and Shape:SolidMolecular weight:375.47Isoindigotin
CAS:<p>Isoindigotin is used in the therapy of Y.</p>Formula:C16H10N2O2Purity:98.14% - ≥95%Color and Shape:SolidMolecular weight:262.26Cyclo(RGDyK) trifluoroacetate
CAS:<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Formula:C31H43F6N9O12Purity:95.28% - ≥95%Color and Shape:SolidMolecular weight:847.72IXA4
CAS:<p>IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1.</p>Formula:C24H28N4O4Purity:99.8% - 99.85%Color and Shape:SolidMolecular weight:436.5Alovudine
CAS:<p>3'-Fluoro-3'-deoxythymidine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis,which is less susceptible to inflammatory changes than FDG.</p>Formula:C10H13FN2O4Purity:99.41%Color and Shape:Less Solid Colourless SolidMolecular weight:244.22STF-083010
CAS:<p>STF-083010 is a selective inhibitor of the IRE1α endonuclease.</p>Formula:C15H11NO3S2Purity:98.09% - 99.45%Color and Shape:SolidMolecular weight:317.381,4-Anthraquinone
CAS:<p>1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.</p>Formula:C14H8O2Purity:95.96% - 97.01%Color and Shape:Orange Brown SolidMolecular weight:208.21BI-1347
CAS:<p>BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.</p>Formula:C22H20N4OPurity:96.7% - 99.63%Color and Shape:SolidMolecular weight:356.42COH29
CAS:<p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>Formula:C22H16N2O5SPurity:97.04% - 98.92%Color and Shape:SolidMolecular weight:420.44Pyridostatin Trihydrochloride
CAS:<p>Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.</p>Formula:C31H35Cl3N8O5Purity:99.69%Color and Shape:SolidMolecular weight:706.02Fialuridine
CAS:<p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>Formula:C9H10FIN2O5Purity:99.71% - 99.88%Color and Shape:Less Crystals Colourless CrystalsMolecular weight:372.09Simeprevir sodium
CAS:<p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>Formula:C38H46N5NaO7S2Purity:98%Color and Shape:SolidMolecular weight:771.92Dasabuvir
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CAS:<p>EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.</p>Formula:C22H18N2O5Purity:97.48%Color and Shape:SolidMolecular weight:390.39
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