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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

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Found 3477 products of "Cell Cycle/Checkpoint"

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  • 10-Formyl-5,8-dideazafolic acid

    CAS:
    <p>10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.</p>
    Formula:C22H21N5O7
    Purity:96.04%
    Color and Shape:Solid
    Molecular weight:467.43
  • RSK-IN-1

    CAS:
    <p>RSK-IN-1 (compound 7d) shows anti-tumor activity. RSK-IN-1 is an inhibitor of RSK that inhibits the phosphorylation of YB-1 [1].</p>
    Formula:C22H17NO2
    Color and Shape:Solid
    Molecular weight:327.38
  • CDK9-IN-15

    CAS:
    <p>CDK9-IN-15: potent CDK9 inhibitor, blocks P-TEFb phosphorylation, inhibits transcription, reduces mRNA, induces tumor cell apoptosis.</p>
    Formula:C16H11N3OS
    Purity:97.24%
    Color and Shape:Solid
    Molecular weight:293.34
  • CTP Synthetase-IN-1

    CAS:
    <p>CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.</p>
    Formula:C20H19F3N6O3S2
    Purity:98.11% - 99.18%
    Color and Shape:Solid
    Molecular weight:512.53
  • SP-471P

    CAS:
    <p>SP-471P inhibits DENV protease; EC50: DENV1-5.9 μM, DENV2-1.4 μM, DENV3-5.1 μM, DENV4-1.7 μM; CC50 &gt;100 μM; lowers viral RNA synthesis.</p>
    Formula:C33H26BrN5O2
    Color and Shape:Solid
    Molecular weight:604.5
  • 15(S)-HpETE

    CAS:
    <p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>
    Formula:C20H32O4
    Color and Shape:Solid
    Molecular weight:336.47
  • Crisnatol

    CAS:
    <p>Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.</p>
    Formula:C23H23NO2
    Color and Shape:Solid
    Molecular weight:345.43
  • Cdc7-IN-17

    CAS:
    <p>Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of &lt;10 μM that can be used in cancer research [1].</p>
    Formula:C13H15N5OS
    Color and Shape:Solid
    Molecular weight:289.36
  • CDK2-IN-13

    CAS:
    <p>CDK2-IN-13: Potent CDK2 inhibitor, arrests cell cycle, induces apoptosis, IC50=12 µM, used in cancer research.</p>
    Formula:C13H12ClN5
    Color and Shape:Soild
    Molecular weight:273.72
  • CCG-257081

    CAS:
    <p>CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.</p>
    Formula:C24H19ClF3N3O2
    Purity:99.76% - 99.94%
    Color and Shape:Solid
    Molecular weight:473.87
  • GW8510

    CAS:
    <p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>
    Formula:C21H15N5O3S2
    Purity:99.32%
    Color and Shape:Solid
    Molecular weight:449.51
  • CBL 0100 free base

    CAS:
    <p>CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.</p>
    Formula:C24H26N2O2
    Purity:98.18% - 98.86%
    Color and Shape:Solid
    Molecular weight:374.48
  • 3'-Deoxyuridine-5'-triphosphate

    CAS:
    <p>3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I &amp; II, with a Ki of 2.0 µM.</p>
    Formula:C9H15N2O14P3
    Color and Shape:Solid
    Molecular weight:468.14
  • CDK8-IN-7

    CAS:
    <p>CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.</p>
    Formula:C30H40N2
    Color and Shape:Solid
    Molecular weight:428.65
  • XVA143

    CAS:
    <p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>
    Formula:C25H21Cl2N3O8
    Color and Shape:Solid
    Molecular weight:562.36
  • IDD388

    CAS:
    <p>IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.</p>
    Formula:C16H12BrClFNO4
    Purity:99.56%
    Color and Shape:Solid
    Molecular weight:416.63
  • Laromustine

    CAS:
    <p>Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.</p>
    Formula:C6H14ClN3O5S2
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:307.78
  • HBV-IN-4

    CAS:
    <p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>
    Formula:C24H19ClFN5O3
    Color and Shape:Solid
    Molecular weight:479.89
  • APC 366

    CAS:
    <p>APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).</p>
    Formula:C22H28N6O4
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:440.5
  • MLAF50

    CAS:
    <p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>
    Formula:C15H12I2O4
    Color and Shape:Solid
    Molecular weight:510.06
  • Cdc7-IN-15

    CAS:
    <p>Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].</p>
    Formula:C12H14N4OS
    Color and Shape:Solid
    Molecular weight:262.33
  • CP681301

    CAS:
    <p>CP681301 is a potent CDK5 inhibitor with anti-tumor effects in Drosophila and reduces Glioma stem cells' growth and renewal.</p>
    Formula:C17H22N4O
    Color and Shape:Solid
    Molecular weight:298.38
  • DNA Gyrase-IN-2

    CAS:
    <p>DNA Gyrase-IN-2 inhibits E. coli (IC50: 3.29-10.49 μM) and M. tuberculosis (IC50: 4.41-5.61 μM) COX, has antibacterial properties.</p>
    Formula:C24H24N8OS2
    Color and Shape:Solid
    Molecular weight:504.63
  • CDK7-IN-15

    CAS:
    <p>CDK7-IN-15, a pyrimidine-based potent CDK7 inhibitor, shows promise for various cancers with defective transcription.</p>
    Formula:C21H24F4N6OS
    Color and Shape:Solid
    Molecular weight:484.51
  • DHODH-IN-15

    CAS:
    <p>DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.</p>
    Formula:C15H11N3O3
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:281.27
  • Beaucage reagent

    CAS:
    <p>Beaucage reagent, which is found to be effective in causing DNA cleavage.</p>
    Formula:C7H4O3S2
    Purity:98.50%
    Color and Shape:White To Off-White Powder
    Molecular weight:200.23
  • WNK1-IN-1

    CAS:
    <p>WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.</p>
    Formula:C13H15BrCl2N2O4S
    Purity:98.09%
    Color and Shape:Solid
    Molecular weight:446.14
  • DNA Gyrase-IN-3

    CAS:
    <p>DNA Gyrase-IN-3 inhibits E. coli DNA gyrase B with IC50 5.41-15.64 μM; shows anti-TB and antibacterial properties.</p>
    Formula:C18H20N6OS2
    Color and Shape:Solid
    Molecular weight:400.52
  • Valategrast hydrochloride

    CAS:
    <p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>
    Formula:C30H33Cl4N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:641.41
  • CH-1504

    CAS:
    <p>CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.</p>
    Formula:C23H23N5O5
    Color and Shape:Solid
    Molecular weight:449.46
  • MMV688844

    CAS:
    <p>MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.</p>
    Formula:C23H25ClN4O2
    Color and Shape:Solid
    Molecular weight:424.92
  • CDK7-IN-10

    CAS:
    <p>CDK7-IN-10: CDK7 inhibitor, IC50&lt;100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)</p>
    Formula:C29H35N7O3
    Color and Shape:Solid
    Molecular weight:529.63
  • CDK7-IN-16

    CAS:
    <p>CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.</p>
    Formula:C19H21F3N6O2S
    Color and Shape:Solid
    Molecular weight:454.47
  • Y-33075

    CAS:
    <p>Y-33075 (Y-39983 free base) is a ROCK inhibitor that lowers IOP, increases blood flow to ONH, and increases the number of RGCs with regenerating axons.</p>
    Formula:C16H16N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:280.32
  • DHX9-IN-1

    CAS:
    <p>DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].</p>
    Formula:C21H21F2N5O3S
    Color and Shape:Solid
    Molecular weight:461.49
  • Tripolin A

    CAS:
    <p>Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)</p>
    Formula:C15H11NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:253.25
  • 5-OHdU

    CAS:
    <p>5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.</p>
    Formula:C9H12N2O6
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:244.2
  • DENV-IN-4

    CAS:
    <p>DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50&gt;100 μM), and strong selectivity (SI&gt;20.9); suppresses DENV2 and RdRp.</p>
    Formula:C28H32N4O4Si
    Color and Shape:Solid
    Molecular weight:516.66
  • CDK9-IN-14

    CAS:
    <p>CDK9-IN-14: Potent CDK9 inhibitor, IC50=6.92 nM, effective on MV-4-11 cells and in vivo tumors, low toxicity, minimal side effects.</p>
    Formula:C21H23F2N3O4
    Color and Shape:Solid
    Molecular weight:419.42
  • ST7612AA1

    CAS:
    <p>ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.</p>
    Formula:C20H27N3O4S
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:405.51
  • 8-Azido-ADP disodium

    CAS:
    <p>8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.</p>
    Formula:C10H13N8NaO10P2
    Color and Shape:Solid
    Molecular weight:490.197
  • Triaziquone

    CAS:
    <p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>
    Formula:C12H13N3O2
    Color and Shape:Solid
    Molecular weight:231.25
  • FAK/aurora kinase-IN-1

    CAS:
    <p>FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].</p>
    Formula:C23H24ClN7O3
    Color and Shape:Solid
    Molecular weight:481.93
  • tBID

    CAS:
    <p>tBID is a selective homeodomain-interacting protein kinase 2 (HIPK2) inhibitor (IC50 of 0.33 μM)</p>
    Formula:C11H3Br4N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.78
  • P18IN003

    CAS:
    <p>P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion of</p>
    Formula:C17H16N2O3
    Purity:98.77%
    Color and Shape:Solid
    Molecular weight:296.32
  • Cdc7-IN-3

    CAS:
    <p>Cdc7-IN-3 is a potent inhibitor of Cdc7 kinase.</p>
    Formula:C20H22N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.41
  • LCAHA

    CAS:
    <p>LCAHA is a USP2a inhibitor. LCAHA inhibits growth of cyclin D1-dependent cells.</p>
    Formula:C24H41NO3
    Color and Shape:Solid
    Molecular weight:391.59
  • Flurocitabine

    CAS:
    <p>Flurocitabine is a therapeutic agent with antineoplastic activity.</p>
    Formula:C9H10FN3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:243.19
  • DHFR-IN-5

    CAS:
    <p>DHFR-IN-5: potent, oral DHFR inhibitor, Ki 0.54 nM against mutant P. falciparum, anti-malarial.</p>
    Formula:C18H24N4O4
    Color and Shape:Solid
    Molecular weight:360.41
  • FN-1501-propionic acid

    CAS:
    <p>FN-1501-propionic acid, a CDK2/9 ligand, in conjunction with a CRBN ligand, has been utilized in the design of a PROTAC CDK2/9 degrader.</p>
    Formula:C25H27N9O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:517.54
  • Zelpolib

    CAS:
    <p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>
    Formula:C22H21N3O5S2
    Purity:98.79%
    Color and Shape:Solid
    Molecular weight:471.55
  • 10-Methyl-10-deazaaminopterin

    CAS:
    <p>10-Methyl-10-deazaaminopterin is a folate analog that shows antitumor activity.</p>
    Formula:C21H23N7O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:453.45
  • N2-Ethylguanosine

    CAS:
    <p>N2-Ethylguanosine is a Nucleoside Derivative - 2-Modified purine nucleoside.</p>
    Formula:C12H17N5O5
    Color and Shape:Solid
    Molecular weight:311.29
  • Y-9738

    CAS:
    <p>Y-9738 is an agent of hypolipidemic.</p>
    Formula:C15H16ClNO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:309.74
  • NSC 693868

    CAS:
    <p>CDKs and GSK-3 inhibitor</p>
    Formula:C9H7N5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:185.19
  • Zaurategrast ethyl ester sulfate

    CAS:
    <p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>
    Formula:C56H60Br2N8O10S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1197.01
  • HBV-IN-22

    CAS:
    <p>HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).</p>
    Formula:C26H29N3O2S2
    Color and Shape:Solid
    Molecular weight:479.66
  • NSC666715

    CAS:
    <p>NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.</p>
    Formula:C15H13Cl2N5O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.33
  • ROCK2-IN-5


    <p>ROCK2-IN-5, a compound blending fasudil, caffeic, and ferulic acids, shows promise for ALS research involving SOD1 mutations.</p>
    Formula:C23H25N3O5S
    Color and Shape:Solid
    Molecular weight:455.53
  • S-(N-PhenethylthiocarbaMoyl)-L-cysteine

    CAS:
    <p>PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.</p>
    Formula:C12H16N2O2S2
    Color and Shape:Solid
    Molecular weight:284.4
  • Aurora A/PKC-IN-1

    CAS:
    <p>Aurora A/PKC-IN-1 inhibits AurA (IC50: 6.9 nM), PKCα (IC50: 16.9 nM), and hinders breast cancer cell growth and spread.</p>
    Formula:C16H14N6OSe2
    Color and Shape:Solid
    Molecular weight:464.24
  • KIRA-7

    CAS:
    <p>KIRA-7: imidazopyrazine, anti-fibrotic, inhibits IRE1α RNase (IC50: 110 nM) allosterically.</p>
    Formula:C27H23FN6O
    Color and Shape:Solid
    Molecular weight:466.51
  • DHODH-IN-1

    CAS:
    <p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>
    Formula:C21H20F3N3O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:403.4
  • BRD9185

    CAS:
    <p>BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.</p>
    Formula:C23H21F6N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:485.42
  • Zaurategrast ethyl ester

    CAS:
    <p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>
    Formula:C28H29BrN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:549.46
  • DHFR-IN-2

    CAS:
    <p>DHFR-IN-2 (4e) is a potent MtDHFR uncompetitive inhibitor with a 7 μM IC50, promising for TB research.</p>
    Formula:C14H13NO2
    Color and Shape:Solid
    Molecular weight:227.26
  • (E/Z)-BIO-acetoxime

    CAS:
    <p>(E/Z)-BIO-acetoxime: potent GSK-3 α/β inhibitor; IC50: GSK-3α/β 10nM, CDK5/p25 2.4μM, CDK2/A 4.3μM, CDK1/B 63μM.</p>
    Formula:C18H12BrN3O3
    Color and Shape:Solid
    Molecular weight:398.21
  • Capzimin

    CAS:
    <p>Capzimin is a selective inhibitor of proteasome isopeptidase Rpn11.</p>
    Formula:C30H24N6O2S4
    Purity:98.31% - 99.32%
    Color and Shape:Solid
    Molecular weight:628.81
  • 8-Deazahomofolic acid

    CAS:
    <p>8-Deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.</p>
    Formula:C21H22N6O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:454.44
  • A 65281

    CAS:
    <p>A 65281: antibacterial isothiazoloquinolone, inhibits P4-unknotting, induces DNA breakage via topoisomerase II.</p>
    Formula:C17H16F2N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.4
  • MFH290

    CAS:
    <p>MFH290 is a selective CDK12/13 inhibitor, covalently bonding with CDK12 Cys-1039, blocks Pol II CTD phosphorylation, and enhances olaparib's efficacy.</p>
    Formula:C26H31N5O3S2
    Color and Shape:Solid
    Molecular weight:525.69
  • RHI002-Me

    CAS:
    <p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>
    Formula:C18H19N3O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:373.49
  • Direct Black 38 free acid

    CAS:
    <p>Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.</p>
    Formula:C34H27N9O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:737.77
  • ROCK-IN-D2

    CAS:
    <p>ROCK-IN-D2 is an effective and selective inhibitor of ROCK.</p>
    Formula:C22H28N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:392.5
  • Atuveciclib S-Enantiomer

    CAS:
    <p>Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.</p>
    Formula:C18H18FN5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:387.43
  • RET-IN-19

    CAS:
    <p>RET-IN-19, a potent RET inhibitor, anticancer: IC50 6.8 nM (RET-wt), 13.51 nM (RET V804M); for NSCLC research.</p>
    Formula:C28H28N6O4S
    Color and Shape:Solid
    Molecular weight:544.62
  • (R)-Filanesib

    CAS:
    <p>(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).</p>
    Formula:C20H22F2N4O2S
    Color and Shape:Solid
    Molecular weight:420.48
  • Apricitabine

    CAS:
    <p>Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-</p>
    Formula:C8H11N3O3S
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:229.26
  • PD 130883

    CAS:
    <p>PD 130883 is a potent lipophilic quinazoline antifolate.</p>
    Formula:C18H15N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:349.34
  • RP-106

    CAS:
    <p>RP-106 is an ATP-competitive inhibitor of CDK5/p25, CDK1/cyclin B, and GSK-3.</p>
    Formula:C17H19N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.35
  • A 65282

    CAS:
    <p>A 65282: antibacterial isothiazoloquinolone, inhibits P4-unknotting, causes DNA breaks via topoisomerase II.</p>
    Formula:C17H16F2N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.4
  • CDK8-IN-10

    CAS:
    <p>CDK8-IN-10 is a selective and potent inhibitor of cell cycle protein-dependent kinase (CDK8) (IC50: 8.25 nM) that can be used to study cancer.</p>
    Formula:C25H15ClF3N5O3
    Color and Shape:Solid
    Molecular weight:525.87
  • CDK4/6-IN-8

    CAS:
    <p>CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM).</p>
    Formula:C18H18N6O5
    Color and Shape:Solid
    Molecular weight:398.37
  • IMB-10

    CAS:
    <p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>
    Formula:C19H15NOS2
    Color and Shape:Solid
    Molecular weight:337.46
  • CRT5

    CAS:
    <p>CRT5, a selective PKD inhibitor, blocks VEGF effects on histone deacetylase 5, CREB, HSP27, and endothelial functions. IC50s: 1-2 nM for PKD1-3.</p>
    Formula:C28H30N4O2
    Color and Shape:Solid
    Molecular weight:454.56
  • AnnH31

    CAS:
    <p>AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the</p>
    Formula:C15H13N3O
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:251.28
  • hDHODH-IN-4

    CAS:
    <p>hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.</p>
    Formula:C21H24N4O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:364.44
  • SC-203885

    CAS:
    <p>SC-203885 is a checkpoint kinase 2 inhibitor.</p>
    Formula:C15H13N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:295.3
  • DHODH-IN-24

    CAS:
    <p>DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].</p>
    Formula:C26H26N4
    Color and Shape:Solid
    Molecular weight:394.51
  • Kira8 Hydrochloride

    CAS:
    <p>Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.</p>
    Formula:C31H30Cl2N6O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:637.58
  • Clociguanil

    CAS:
    <p>Clociguanil has antimalarial activity.</p>
    Formula:C12H15Cl2N5O
    Color and Shape:Solid
    Molecular weight:316.19
  • CDK4/6-IN-12

    CAS:
    <p>CDK4/6-IN-12 inhibits CDK4/6 with IC50s of 592.3 nM &amp; 3090 nM, useful in cancer research.</p>
    Formula:C12H10N6
    Color and Shape:Solid
    Molecular weight:238.25
  • Tenofovir exalidex

    CAS:
    <p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>
    Formula:C28H52N5O5P
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:569.72
  • BPIC

    CAS:
    <p>BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.</p>
    Formula:C27H20N2O5
    Color and Shape:Solid
    Molecular weight:452.46
  • Levofloxacin sodium

    CAS:
    <p>Levofloxacin sodium: synthetic antibacterial, stops DNA replication by inhibiting bacterial DNA gyrase.</p>
    Formula:C18H20FN3NaO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:384.363
  • FRα-IN-1

    CAS:
    <p>FRα-IN-1 (Compound 4) is a tumour targeting agent. FRα-IN-1 exhibits selective anti-cancer effects on FRα and FRβ expressing cells.</p>
    Formula:C21H24N6O6
    Color and Shape:Solid
    Molecular weight:456.45
  • CLK1-IN-2


    <p>CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.</p>
    Formula:C16H12Cl2N2O2S
    Color and Shape:Solid
    Molecular weight:367.25
  • TDRL-X80

    CAS:
    <p>TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).</p>
    Formula:C23H15ClN2O6
    Color and Shape:Solid
    Molecular weight:450.83
  • Metioprim

    CAS:
    <p>Metioprim is a competitive bacterial dihydrofolate reductases inhibitor.</p>
    Formula:C14H18N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:306.38
  • XL-188

    CAS:
    <p>XL-188: Potent, selective USP7 inhibitor, IC50 = 193 nM (domain), 90 nM (full). Boosts p53, p21; degrades HDM2. Unique among DUB inhibitors.</p>
    Formula:C32H42N6O4
    Color and Shape:Solid
    Molecular weight:574.71
  • Nucleoside-Analog-1

    CAS:
    <p>Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.</p>
    Formula:C9H9N5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:267.2
  • L-Fd4A

    CAS:
    <p>L-Fd4A (compound 36) is an adenine derivative with anti-HIV (EC50=1.5μM) and anti-HBV (EC50=1.7μM) effects, low cytotoxicity.</p>
    Formula:C10H10FN5O2
    Color and Shape:Solid
    Molecular weight:251.22
  • BPKDi

    CAS:
    <p>BPKDi is a potent and selective inhibitor of PKD (protein kinase D).</p>
    Formula:C21H28N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:380.49
  • Aloisine A

    CAS:
    <p>Aloisine A, a CDK/GSK-3 inhibitor with IC50: Cdk1/B-150nM, Cdk2/A-120nM, Cdk2/E-400nM, Cdk5/25-200nM, Cdk5/35-160nM, GSK-3α-500nM, GSK-3β-650nM, JNK-3-10μM.</p>
    Formula:C16H17N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:267.33
  • CCT068127

    CAS:
    <p>CCT068127 is a potent CDK2 and CDK9 inhibitor.</p>
    Formula:C19H27N7O
    Color and Shape:Solid
    Molecular weight:369.46
  • hDHODH-IN-5

    CAS:
    <p>hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).</p>
    Formula:C21H21F3N2O2
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:390.4
  • DHODH-IN-13

    CAS:
    <p>DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.</p>
    Formula:C10H6F3N3O3
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:273.17
  • (S)-CR8

    CAS:
    <p>(S)-CR8 is an effective second-generation cyclin-dependent kinase inhibitor.</p>
    Formula:C24H29N7O
    Color and Shape:Solid
    Molecular weight:431.53
  • hDHODH-IN-3

    CAS:
    <p>hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.</p>
    Formula:C18H19BrN4O2
    Purity:99.871%
    Color and Shape:Solid
    Molecular weight:403.27
  • BMVC

    CAS:
    <p>BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.</p>
    Formula:C28H25I2N3
    Color and Shape:Solid
    Molecular weight:657.33
  • TP1287

    CAS:
    <p>TP-1287 is an oral phosphate prodrug of the CDK9 inhibitor, alvocidib.</p>
    Formula:C21H21ClNO8P
    Color and Shape:Solid
    Molecular weight:481.82
  • L-Cytidine

    CAS:
    <p>L-Cytidine, pyrimidine nucleoside in RNA, regulates glial glutamate, brain lipids, catecholamines, and mitochondria.</p>
    Formula:C9H13N3O5
    Color and Shape:Solid
    Molecular weight:243.22
  • CDK2-IN-11

    CAS:
    <p>CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.</p>
    Formula:C18H14ClN7O2S
    Color and Shape:Solid
    Molecular weight:427.87
  • Braco-19 trihydrochloride

    CAS:
    <p>BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.</p>
    Formula:C35H46Cl3N7O2
    Purity:98.74%
    Color and Shape:Solid
    Molecular weight:703.14
  • (S)-LY3177833 hydrate

    CAS:
    <p>(S)-LY3177833 ((S)-Example 2) hydrate, an orally active CDC7 kinase inhibitor, exhibits extensive in vitro anticancer efficacy.</p>
    Formula:C16H14FN5O2
    Color and Shape:Solid
    Molecular weight:327.31
  • Bofumustine

    CAS:
    <p>Bofumustine is a chloroethyl nitrosourea with anti tumor properties.</p>
    Formula:C18H21ClN4O9
    Color and Shape:Solid
    Molecular weight:472.83
  • Levoleucovorin disodium

    CAS:
    <p>Levoleucovorin disodium is the sodium salt of the enantiomerically active form of Folinic Acid.</p>
    Formula:C20H21N7Na2O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:517.41
  • Nitracrine

    CAS:
    <p>Nitracrine: a 1-nitroacridine, hypoxia-selective, anti-tumor agent; inhibits RNA synthesis, binds DNA reversibly and forms covalent adducts.</p>
    Formula:C18H20N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.38
  • ProTAME

    CAS:
    <p>ProTAME inhibits APC/CFzr &amp; APC/CCdc20, enhances cell death with doxorubicin/etoposide in primary/MM cells, especially after TOPIIα upregulation.</p>
    Formula:C34H38N4O12S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:726.75
  • Eg5 Inhibitor V, trans-24

    CAS:
    <p>Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.</p>
    Formula:C26H21N3O3
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:423.46
  • DDD100097

    CAS:
    <p>DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.</p>
    Formula:C22H30Cl2F2N4O2S
    Purity:98.89%
    Color and Shape:Solid
    Molecular weight:523.47
  • LY 222306

    CAS:
    <p>LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.</p>
    Formula:C19H23N5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:433.42
  • Ipivivint

    CAS:
    <p>Ipivivint: orally active, potent CLK inhibitor; hinders CLK1, CLK2, &amp; CLK3; curbs Wnt signaling &amp; SRSF phosphorylation for cancer research.</p>
    Formula:C26H21FN8
    Color and Shape:Solid
    Molecular weight:464.5
  • DHODH-IN-8

    CAS:
    <p>DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).</p>
    Formula:C17H13ClN2O2
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:312.75
  • AS-136A

    CAS:
    <p>AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.</p>
    Formula:C17H19F3N4O3S
    Purity:98.52%
    Color and Shape:Solid
    Molecular weight:416.42
  • Synucleozid

    CAS:
    <p>Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.</p>
    Formula:C22H20N6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.43
  • OM-137

    CAS:
    <p>OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.</p>
    Formula:C13H14N4O3S
    Color and Shape:Solid
    Molecular weight:306.34
  • VRX-0466617

    CAS:
    <p>VRX-0466617 is a novel selective Chk2 inhibitor.</p>
    Formula:C19H20BrN5O2S
    Color and Shape:Solid
    Molecular weight:462.36
  • CDK2-IN-12

    CAS:
    <p>CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.</p>
    Formula:C20H17N9O2S
    Color and Shape:Solid
    Molecular weight:447.47
  • CDK8-IN-6

    CAS:
    <p>CDK8-IN-6 (compound 9) is a potent inhibitor of cyclin-dependent kinase 8 (CDK8) (Kd: 13 nM), CDK8-IN-6 showed potential research value in AML cancers.</p>
    Formula:C26H37ClN2
    Color and Shape:Solid
    Molecular weight:413.04
  • KH-CB19

    CAS:
    <p>KH-CB19 is an effective and highly specific inhibitor of the CDC2-like kinase isoforms 1 and 4 (CLK1/CLK4).</p>
    Formula:C15H13Cl2N3O2
    Color and Shape:Solid
    Molecular weight:338.19
  • Dyrk1A-IN-3

    CAS:
    <p>Dyrk1A-IN-3 is a selective DYRK1A inhibitor with an IC50 of 76 nM, useful for neurodegenerative disease research.</p>
    Formula:C18H16N6
    Color and Shape:Solid
    Molecular weight:316.36
  • 3,6-DMAD dihydrochloride

    CAS:
    <p>3,6-DMAD dihydrochloride: Potent IRE1α-XBP1s inhibitor, affects IL-6 secretion and RNase activity, used in cancer research.</p>
    Formula:C22H33Cl2N5
    Color and Shape:Solid
    Molecular weight:438.44
  • CDK5 inhibitor 20-223

    CAS:
    <p>CDK5 inhibitor 20-223 is a potent CDK2/CDK5 inhibitor,anti-Colorectal Cancer (CRC), inhibiting cell migration and inducing cell cycle arrest.</p>
    Formula:C19H19N3O
    Color and Shape:Solid
    Molecular weight:305.37
  • PF-4950834

    CAS:
    <p>PF-4950834, a ATP-competitive, selective Rho kinase inhibitor, provides therapeutic benefits in chronic inflammatory diseases.</p>
    Formula:C21H19N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:345.39
  • PV-1115

    CAS:
    <p>PV-1115 is an effective and highly selective inhibitor of the Chk2.</p>
    Formula:C20H19N7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:405.41
  • 2-Fluoroadenine

    CAS:
    <p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>
    Formula:C5H4FN5
    Purity:98.84% - 99.62%
    Color and Shape:White To Light Yellow Crystal Powder
    Molecular weight:153.12
  • HIV-1 inhibitor-43

    CAS:
    <p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), &lt;0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>
    Formula:C24H21ClN2O4S
    Color and Shape:Solid
    Molecular weight:468.95
  • Litronesib Racemate

    CAS:
    <p>Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.</p>
    Formula:C23H37N5O4S2
    Color and Shape:Solid
    Molecular weight:511.7
  • GP29

    CAS:
    <p>GP29 is a Type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.</p>
    Formula:C33H28F3N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:599.6
  • BMVC2

    CAS:
    <p>BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.</p>
    Formula:C28H25I2N3
    Color and Shape:Solid
    Molecular weight:657.33
  • BMH-22

    CAS:
    <p>BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>
    Formula:C16H17N3
    Color and Shape:Solid
    Molecular weight:251.33
  • MSC-1186

    CAS:
    <p>MSC-1186 selectively inhibits SRPKs—IC50: 2.7nM (SRPK1), 81nM (SRPK2), 0.6nM (SRPK3)—for cancer research.</p>
    Formula:C19H17ClFN7O2S
    Color and Shape:Solid
    Molecular weight:461.9
  • (Rac)-Managlinat dialanetil

    CAS:
    <p>Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.</p>
    Formula:C21H33N4O6PS
    Purity:98.52%
    Color and Shape:Solid
    Molecular weight:500.55
  • Carbonic anhydrase inhibitor 14

    CAS:
    <p>CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.</p>
    Formula:C18H17N7O2S
    Color and Shape:Solid
    Molecular weight:395.44
  • DHODH-IN-12

    CAS:
    <p>DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.</p>
    Formula:C10H9N3O2
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:203.2
  • Bis-Pro-5FU

    CAS:
    <p>Bis-Pro-5FU enhances oral uptake and safety of 5-FU, an anti-cancer drug for colorectal and pancreatic tumors.</p>
    Formula:C10H7FN2O2
    Color and Shape:Solid
    Molecular weight:206.17
  • DHODH-IN-20

    CAS:
    <p>Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.</p>
    Formula:C24H25F4N3O3
    Color and Shape:Solid
    Molecular weight:479.47
  • CGP 53353

    CAS:
    <p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>
    Formula:C20H13F2N3O2
    Purity:98.11%
    Color and Shape:Solid
    Molecular weight:365.33
  • Fozivudine tidoxil

    CAS:
    <p>Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>
    Formula:C35H64N5O8PS
    Color and Shape:Solid
    Molecular weight:745.95
  • JFN05510

    CAS:
    <p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>
    Formula:C50H68N7O9PSi
    Color and Shape:Solid
    Molecular weight:970.18
  • Aditoprime

    CAS:
    <p>Aditoprime inhibits bacterial growth by blocking DHFR, effective against L.casei and E.coli with IC50 of 520/47 nM.</p>
    Formula:C15H21N5O2
    Color and Shape:Solid
    Molecular weight:303.36
  • PKC-9

    CAS:
    <p>PKC-9 is a PKC-zeta inhibitor 9.</p>
    Formula:C25H25N7
    Color and Shape:Solid
    Molecular weight:423.51
  • 2-Keto-D-galactose

    CAS:
    <p>2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.</p>
    Formula:C6H10O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:178.14
  • CAP-53194

    CAS:
    <p>CAP-53194 is a selective Plk1 inhibitor.</p>
    Formula:C21H14N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:430.37
  • GSK-3008348

    CAS:
    <p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>
    Formula:C29H37N5O2
    Purity:99.547%
    Color and Shape:Solid
    Molecular weight:487.64
  • Mivobulin Isethionate

    CAS:
    <p>Mivobulin, a tubulin inhibitor (CI-980), may treat glioma, melanoma, prostate, and ovarian cancer, targeting colchicine-binding site.</p>
    Formula:C19H25N5O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:451.5
  • BAY-707

    CAS:
    <p>BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.</p>
    Formula:C15H20N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:288.34
  • Picoplatin

    CAS:
    <p>Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.</p>
    Formula:C6H10Cl2N2Pt
    Purity:98%
    Color and Shape:Solid
    Molecular weight:376.14
  • HHL-6

    CAS:
    <p>HHL-6 is a c-Fos and BDNF protein expression modulator.</p>
    Formula:C19H26N2O3
    Color and Shape:Solid
    Molecular weight:330.42
  • Fosteabine

    CAS:
    <p>Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase.</p>
    Formula:C27H50N3O8P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:575.67
  • Metralindole HCl

    CAS:
    <p>Metralindole is a reversible monoamine oxidase A (RIMA) inhibitor, it was investigated as a potential antidepressant.</p>
    Formula:C15H18ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:291.78
  • HR22C16

    CAS:
    <p>HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.</p>
    Formula:C23H23N3O3
    Color and Shape:Solid
    Molecular weight:389.45
  • HIPP

    CAS:
    <p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>
    Formula:C9H9NO3
    Color and Shape:Solid
    Molecular weight:179.17
  • NPD9948

    CAS:
    <p>NPD9948 is a competitive inhibitor of MTH1.</p>
    Formula:C13H14N6
    Color and Shape:Solid
    Molecular weight:254.29
  • LDN-209929

    CAS:
    <p>LDN-209929 2HCl is a potent and selective inhibitor of haspin kinase.</p>
    Formula:C17H17ClN2OS
    Color and Shape:Solid
    Molecular weight:332.85
  • DYRKi

    CAS:
    <p>DYRKi is a nontoxic, DYRK1-selective inhibitor.</p>
    Formula:C20H13F3N4O2S
    Color and Shape:Solid
    Molecular weight:430.4
  • BIPM

    CAS:
    <p>BIPM inhibits ROCK2, alters SH-SY5Y cell migration, actin fibers, neurite length, and reduces cofilin phosphorylation.</p>
    Formula:C23H22N2O3
    Color and Shape:Solid
    Molecular weight:374.43
  • Cdc7-IN-14

    CAS:
    <p>Cdc7-IN-14 (compound 82) is a potent CDC7 inhibitor with an IC50 &lt; 1 nM, promising for cancer research.</p>
    Formula:C18H20N4O2S
    Color and Shape:Solid
    Molecular weight:356.44
  • Rho-Kinase-IN-2

    CAS:
    <p>Rho-Kinase-IN-2, an oral ROCK inhibitor (IC50=3nM), penetrates the CNS; potential in Huntington's research.</p>
    Formula:C20H25FN4O2
    Color and Shape:Solid
    Molecular weight:372.44
  • L-Guanosine

    CAS:
    <p>L-Guanosine is the L-configuration of Guanosine. Guanosine is a purine nucleoside that has anti-herpesvirus activity [1] [2].</p>
    Formula:C10H13N5O5
    Color and Shape:Solid
    Molecular weight:283.24
  • REV7/REV3L-IN-1

    CAS:
    <p>REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),</p>
    Formula:C19H21N3O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:371.45
  • NSC47924

    CAS:
    <p>NSC47924 is a laminin receptor (LR) inhibitor.</p>
    Formula:C18H17NO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:279.33
  • AB-182

    CAS:
    <p>AB-182 is an aziridine derivative with antitumor activity.</p>
    Formula:C11H22N3O4P
    Color and Shape:Solid
    Molecular weight:291.28
  • Ro 43-5054

    CAS:
    <p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>
    Formula:C24H27N5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:497.5
  • ROCK-IN-D1

    CAS:
    <p>ROCK-IN-D1 is an effective and selective inhibitor of ROCK.</p>
    Formula:C22H27N5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:425.55
  • UIAA-II-232

    CAS:
    <p>UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).</p>
    Formula:C20H24FN5O3
    Color and Shape:Solid
    Molecular weight:401.43
  • Protein kinase D inhibitor 1

    CAS:
    <p>Protein kinase D inhibitor 1 (17m) is a potent pan-PKD suppressant with IC50 of 17-35 nM, targeting cortactin phosphorylation.</p>
    Formula:C19H21N7
    Color and Shape:Solid
    Molecular weight:347.42
  • SNX2-1-108

    CAS:
    <p>SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.</p>
    Formula:C21H16N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.38
  • LIMK-IN-14

    CAS:
    <p>LIMK-IN-14 is an effective and selective inhibitor of LIMK.</p>
    Formula:C22H27N7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:437.49
  • Denopterin

    CAS:
    <p>Denopterin is an antineoplastic agent.</p>
    Formula:C21H23N7O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:469.45
  • RK-9123016

    CAS:
    <p>RK-9123016 is a SIRT2 inhibitor.</p>
    Formula:C16H18N6O3S
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:374.42
  • 1-Acetyl-3-o-toluyl-5-fluorouracil

    CAS:
    <p>1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.</p>
    Formula:C14H11FN2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:290.25
  • MK-0668

    CAS:
    <p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>
    Formula:C31H30Cl2N6O6S
    Color and Shape:Solid
    Molecular weight:685.58
  • BI-831266

    CAS:
    <p>BI-831266 is a potent and selective Aurora kinase B inhibitor.</p>
    Formula:C27H38ClN7O2
    Color and Shape:Solid
    Molecular weight:528.09
  • Aurora Kinases-IN-2

    CAS:
    <p>Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.</p>
    Formula:C22H18ClN5O3
    Color and Shape:Solid
    Molecular weight:435.86
  • Rabacfosadine succinate

    CAS:
    <p>Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.</p>
    Formula:C25H41N8O10P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:644.623
  • Thiamiprine

    CAS:
    <p>Thiamiprine is an agent with the activity of antineoplastic.</p>
    Formula:C9H8N8O2S
    Color and Shape:Solid
    Molecular weight:292.28
  • Meturedepa

    CAS:
    <p>Meturedepa is an antineoplastic agent.</p>
    Formula:C11H22N3O3P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:275.28
  • BMH-23

    CAS:
    <p>BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>
    Formula:C15H15N3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:237.3
  • (R)-DRF053 dihydrochloride

    CAS:
    <p>cdk/CK1 inhibitor,potent and ATP-competitive</p>
    Formula:C23H29Cl2N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:490.43
  • BzDANP

    CAS:
    <p>BzDANP is a modulator of pre-miR-29a maturation by Dicer.</p>
    Formula:C18H24N6
    Color and Shape:Solid
    Molecular weight:324.42
  • L 703014

    CAS:
    <p>L 703014 is an antagonist of the fibrinogen receptor.</p>
    Formula:C24H34N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:442.55
  • SEC inhibitor KL-2

    CAS:
    <p>KL-2: potent SEC inhibitor, selectively disrupts AFF4-CCNT1, dose-dependent, Ki: 1.50 μM.</p>
    Formula:C17H13ClFNO3
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:333.74
  • Aurora kinase inhibitor-9

    CAS:
    <p>Aurora kinase inhibitor-9 (9d) targets AURKA/B with IC50: 0.093 μM for A and 0.09 μM for B, with wide anti-proliferative effects.</p>
    Formula:C19H17Cl2N3O4S
    Color and Shape:Solid
    Molecular weight:454.33
  • PV-1019

    CAS:
    <p>PV-1019 (NSC 744039), a potent Chk2 inhibitor, has an IC50 of 24 nM and blocks Chk2 autophosphorylation and IR-induced apoptosis.</p>
    Formula:C18H17N7O3
    Color and Shape:Solid
    Molecular weight:379.37
  • LSN 3213128

    CAS:
    <p>LSN 3213128: a potent oral antifolate targeting AICARFT with IC50s of 16 nM (enzyme) and 19 nM (cells), offers anti-tumor effects.</p>
    Formula:C17H16FN3O4S2
    Color and Shape:Solid
    Molecular weight:409.45
  • JTK-101

    CAS:
    <p>JTK-101 is a potent and selective Tat-dependent HIV-1 replication inhibitor.</p>
    Formula:C25H23N3O3
    Color and Shape:Solid
    Molecular weight:413.47
  • Scaff10-8

    CAS:
    <p>Scaff10-8 blocks AKAP-Lbc-RhoA, aiding aquaporin-2 movement in kidney cells.</p>
    Formula:C22H18O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:378.37
  • LDN-209929 dihydrochloride

    CAS:
    <p>LDN-209929 dihydrochloride: potent haspin kinase inhibitor, 55 nM IC50, 180x more selective than DYRK2.</p>
    Formula:C17H19Cl3N2OS
    Color and Shape:Solid
    Molecular weight:405.77