Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(94 products)
- CDK(500 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(261 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(70 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
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Found 3477 products of "Cell Cycle/Checkpoint"
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D-Xylofuranose, 1,2,3,5-tetraacetate
CAS:<p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.</p>Formula:C13H18O9Color and Shape:SolidMolecular weight:318.28Myt1-IN-1
CAS:<p>Myt1-IN-1 has anticancer effects that is a potent inhibitor of Myt1 with an IC 50 of <10 nM [1].</p>Formula:C16H15ClN4O2Color and Shape:SolidMolecular weight:330.77AM-TS23
CAS:<p>AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.</p>Formula:C17H12N2O3S3Purity:98%Color and Shape:SolidMolecular weight:388.48ML366
CAS:<p>ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.</p>Formula:C17H19N3O4Purity:98%Color and Shape:SolidMolecular weight:329.35HBX28258
CAS:<p>HBX28258, a human USP7 inhibitor, binds covalently and selectively deactivates USP7 in colon cancer and kidney cells.</p>Formula:C26H30ClN3OPurity:98%Color and Shape:SolidMolecular weight:435.99JNJ-9676
CAS:<p>JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.</p>Formula:C28H21F2N5O2Purity:99.83%Color and Shape:SoildMolecular weight:497.5DHODH-IN-3
CAS:<p>DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.</p>Formula:C17H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:312.75OXA-06 Dihydrochloride
CAS:<p>OXA-06 Dihydrochloride is a PANC-1 cell migration and MYPT1 phosphorylation inhibitor.</p>Formula:C21H18FN3Purity:98%Color and Shape:SolidMolecular weight:331.39Lysine-methotrexate
CAS:<p>Lysine-methotrexate is an anticancer drug. It is an inhibitor of dihydrofolate reductase.</p>Formula:C21H27N9O3Purity:98%Color and Shape:SolidMolecular weight:453.5Type II topoisomerase inhibitor 1
CAS:<p>Potent E. coli DNA gyrase inhibitor (IC50: 1.7 nM), targets Asp73; weak topoisomerase IV inhibitor (IC50: 0.98 μM).</p>Formula:C18H15N3O4Color and Shape:SolidMolecular weight:337.33Ulecaciclib
CAS:<p>Ulecaciclib: oral, BBB-permeable CDK inhibitor; favorable pharmacokinetics; ki: 0.62 μM (CDK2/A), 3 nM (CDK6/D3), 0.2 nM (CDK4/D1), 0.63 μM (CDK7/H).</p>Formula:C25H33FN8SColor and Shape:SolidMolecular weight:496.65LY 207702
CAS:<p>LY 207702, a difluorinated purine nucleoside, exhibits antitumor activity in preclinical models.</p>Formula:C10H12F2N6O3Purity:98%Color and Shape:SolidMolecular weight:302.24Codon readthrough inducer 1
CAS:<p>Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.</p>Formula:C15H11N3O5Purity:98%Color and Shape:SolidMolecular weight:313.26MS0017509
CAS:<p>MS0017509 is a DNA damage repair inhibitor.</p>Formula:C11H10N4Purity:98%Color and Shape:SolidMolecular weight:198.22Cdc7-IN-13
CAS:<p>Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].</p>Formula:C18H20N4O2SColor and Shape:SolidMolecular weight:356.44AZD7762 HCl
CAS:<p>AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.</p>Formula:C17H20ClFN4O2SPurity:98%Color and Shape:SolidMolecular weight:398.882'-Fluorothymidine
CAS:<p>2'-Fluorothymidine is a selective substrate for TK2, related to thymidine and methyluridine.</p>Formula:C10H13FN2O5Purity:99.67%Color and Shape:SolidMolecular weight:260.22GR 144053 trihydrochloride
CAS:<p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>Formula:C18H30Cl3N5O2Purity:98%Color and Shape:SolidMolecular weight:454.82VPC-70619
CAS:<p>VPC-70619: Oral, selective N-Myc inhibitor; blocks cancer growth by hindering N-Myc-Max/DNA binding; well-absorbed.</p>Formula:C16H8ClF3N4OColor and Shape:SolidMolecular weight:364.71Tetrahydrouridine
CAS:<p>Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.</p>Formula:C9H16N2O6Purity:98%Color and Shape:SolidMolecular weight:248.23Cdc7-IN-9
CAS:<p>Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].</p>Formula:C15H17N5OSColor and Shape:SolidMolecular weight:315.39CID 5951923
CAS:<p>CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.</p>Formula:C16H18N2O7SPurity:99.95%Color and Shape:SolidMolecular weight:382.39DAP-81
CAS:<p>DAP-81, a diaminopyrimidine, inhibits Plk1 (IC50: 0.9 nM), disrupts microtubules, causes monopolar spindles; in preclinical studies.</p>Formula:C25H20N6O4Color and Shape:SolidMolecular weight:468.46CDK4/6-IN-9
CAS:<p>CDK4/6-IN-9 selectively inhibits CDK4/6 (IC50: 905 nM); potential for MM research.</p>Formula:C22H23FN8Color and Shape:SolidMolecular weight:418.47HBV-IN-16
CAS:<p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>Formula:C22H20ClNO4Color and Shape:SolidMolecular weight:397.85CDK7-IN-12
CAS:<p>CDK7-IN-12 inhibits CDK7 to control transcription and cell cycle, halting tumor growth in vitro/vivo with cancer research potential.</p>Formula:C20H19F3N6Color and Shape:SolidMolecular weight:400.4Phelorphan
CAS:<p>Phelorphan is an inhibitor of enkephalinase.</p>Formula:C20H22N2O4SPurity:98%Color and Shape:SolidMolecular weight:386.46Crisnatol mesylate
CAS:<p>Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.</p>Formula:C24H27NO5SColor and Shape:SolidMolecular weight:441.54BAY-958
CAS:<p>BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.</p>Formula:C17H16FN5O3SPurity:98%Color and Shape:SolidMolecular weight:389.4Werner syndrome RecQ helicase-IN-3
CAS:<p>Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.</p>Formula:C31H30ClF3N8O5Color and Shape:SolidMolecular weight:687.07CFM-1
CAS:<p>CFM-1 is an antagonist of the anaphase-promoting complex (APC)-2. It also is a cell cycle and apoptosis regulatory protein (CARP)-1 interaction antagonist.</p>Formula:C12H7BrN2O2S2Purity:98%Color and Shape:SolidMolecular weight:355.23Mps-BAY2b
CAS:<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Formula:C20H23N5OColor and Shape:SolidMolecular weight:349.43Indirubin-5-sulfonate
CAS:<p>Indirubin-5-sulfonate inhibits GSK-3β & CDKs with IC50: 55/35/150/300/65 nM for CDK1/B, 2/A&E, 4/D1, 5/p35.</p>Formula:C16H10N2O5SPurity:98%Color and Shape:SolidMolecular weight:342.33RUC-1
CAS:<p>RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.</p>Formula:C11H15N5OSPurity:98%Color and Shape:SolidMolecular weight:265.33Homocarbonyltopsentin
CAS:<p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>Formula:C21H14N4O3Purity:98%Color and Shape:SolidMolecular weight:370.36Guanoctine hydrochloride
CAS:<p>Guanoctine hydrochloride has antihypertensive activity.</p>Formula:C9H22ClN3Color and Shape:SolidMolecular weight:207.74NSC 109555 ditosylate
CAS:<p>Chk2 inhibitor,ATP-competitive</p>Formula:C26H32N10O4SPurity:98%Color and Shape:SolidMolecular weight:580.6614α-Demethylase/DNA Gyrase-IN-2
CAS:<p>14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.</p>Formula:C24H22N4O4Color and Shape:SolidMolecular weight:430.46BDM44768
CAS:<p>BDM44768 is an insulin-degrading enzyme (IDE) inhibitor that acts by inducing glucose intolerance.</p>Formula:C24H22FN5O3Color and Shape:SolidMolecular weight:447.46IRE1α kinase-IN-3
CAS:<p>IRE1α kinase-IN-3 is a potent, ATP-competitive inhibitor of IRE1α (Ki: 480 nM).</p>Formula:C29H32N6O3SColor and Shape:SolidMolecular weight:544.67Mps1-IN-4
CAS:<p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>Formula:C26H31F3N6O2Color and Shape:SolidMolecular weight:516.56CDK7-IN-8
CAS:<p>CDK7-IN-8 is a potent inhibitor of CDK7 (IC50: 54.29 nM) and exhibits inhibitory activity against several cancer cells and in vivo tumor models.</p>Formula:C25H38N8O3Color and Shape:SolidMolecular weight:498.62Nucleoside-Analog-2
CAS:<p>Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.</p>Formula:C9H11N5O6Purity:98%Color and Shape:SolidMolecular weight:285.212'-Deoxy-L-guanosine
CAS:<p>2'-Deoxy-L-guanosine is a nucleoside that shows antibiotic properties by inhibiting protein synthesis, leading to cell death.</p>Formula:C10H13N5O4Color and Shape:SolidMolecular weight:267.24VE-465
CAS:<p>VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.</p>Formula:C22H28N8OSColor and Shape:SolidMolecular weight:452.58Antitumor agent-85
<p>Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.</p>Formula:C24H33N7Color and Shape:SolidMolecular weight:419.57XU1
CAS:<p>XU1（Benzo[c][1,8]naphthyridin-6(5h)-One） is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for inhibition, regulation or</p>Formula:C12H8N2OPurity:98.58% - 99.59%Color and Shape:SolidMolecular weight:196.2HBV-IN-15
CAS:<p>HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.</p>Formula:C24H23ClO6Color and Shape:SolidMolecular weight:442.89PD-1-IN-22
CAS:<p>PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).</p>Formula:C25H25N5O4Purity:99.51%Color and Shape:SolidMolecular weight:459.5TC-Mps1-12
CAS:<p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>Formula:C17H20N6OPurity:98%Color and Shape:SolidMolecular weight:324.38CB 3717
CAS:<p>CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.</p>Formula:C24H23N5O6Color and Shape:SolidMolecular weight:477.47Pyrazofurin
CAS:<p>Pyrazofurin, a pyrimidine analogue, blocks cell growth and DNA synthesis by targeting UMP synthase & orotate-phosphoribosyltransferase (IC50: 0.06-0.37 μM).</p>Formula:C9H13N3O6Purity:98%Color and Shape:SolidMolecular weight:259.22IPR-803
CAS:<p>IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.</p>Formula:C27H23N3O4Purity:95%Color and Shape:SolidMolecular weight:453.49Datelliptium chloride
CAS:<p>Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.</p>Formula:C23H28ClN3OPurity:98%Color and Shape:SolidMolecular weight:397.94Sibrafiban
CAS:<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Formula:C20H28N4O6Color and Shape:SolidMolecular weight:420.46CFI-400437
CAS:<p>CFI-400437 is an ATP-competitive PLK4 inhibitor (IC50: 0.6 nM) and is an indolequinone derivative.</p>Formula:C29H28N6O2Color and Shape:SolidMolecular weight:492.57IACS-4759
CAS:<p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>Formula:C10H17N3O2Color and Shape:SolidMolecular weight:211.26FINDY
CAS:<p>FINDY selectively inhibits DYRK1A at 35 μM IC50, blocking Ser97 autophosphorylation, useful for neurological disorder research.</p>Formula:C16H17NO2S2SiColor and Shape:SolidMolecular weight:347.53CDK-IN-10
CAS:<p>CDK-IN-10 is a cell cycle protein-dependent kinase (CDK) inhibitor with potential anticancer activity for cancer research.</p>Formula:C18H18N4O2Purity:97.07%Color and Shape:SolidMolecular weight:322.36SR7826
CAS:<p>SR7826 is a selective LIMK inhibitor.</p>Formula:C22H21N5O2Purity:98%Color and Shape:SolidMolecular weight:387.43MtTMPK-IN-6
CAS:<p>MtTMPK-IN-6 inhibits M. tuberculosis thymidylate kinase with IC50 of 29 μM, promising for TB research.</p>Formula:C23H25N3O3Color and Shape:SolidMolecular weight:391.46ERCC1-XPF-IN-1
CAS:<p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>Formula:C28H32ClN5O2Color and Shape:SolidMolecular weight:506.04CLT-28643
CAS:<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Formula:C19H17N3O4Purity:99.89%Color and Shape:SolidMolecular weight:351.36ML372
CAS:<p>ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.</p>Formula:C18H20N2O4SColor and Shape:SolidMolecular weight:360.43BMS-587101
CAS:<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Formula:C26H20Cl2N4O4SColor and Shape:SolidMolecular weight:555.43PFM03
CAS:<p>PFM03 is a endonuclease inhibitor that specifically blocks Mre11,reduce MRN endonuclease activity, blocking hMRN-mediated endonucleotomy and nuclear exocytosis.</p>Formula:C14H15NO2S2Purity:99.81% - 99.98%Color and Shape:SolidMolecular weight:293.4c-Myc inhibitor 9
CAS:<p>c-Myc inhibitor 9 (compound 332) with logEC50 ≥6, suppresses tumors in mice, useful for cancer research.</p>Formula:C27H31N5OSColor and Shape:SolidMolecular weight:473.63CDK7-IN-20
<p>CDK7-IN-20: potent, irreversible CDK7 inhibitor, IC50 of 4nM, 206x selectivity vs. other CDKs, potential for ADPKD study.</p>Formula:C30H26N6O3Color and Shape:SolidMolecular weight:518.57Integrin modulator 1
CAS:<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Formula:C13H14N2O4Purity:99.61%Color and Shape:SolidMolecular weight:262.26EMD534085
CAS:<p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>Formula:C25H31F3N4O2Purity:98%Color and Shape:SolidMolecular weight:476.53Chrysotobibenzyl
CAS:<p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>Formula:C19H24O5Color and Shape:SolidMolecular weight:332.39XMD-17-51
CAS:<p>XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.</p>Formula:C21H24N8OPurity:99.04%Color and Shape:SoildMolecular weight:404.478RK64
CAS:<p>8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) .</p>Formula:C14H16N8O2SColor and Shape:SolidMolecular weight:360.45,10-Dideazafolic acid
CAS:<p>5,10-Dideazafolic acid is an antileukemic drug.</p>Formula:C21H21N5O6Color and Shape:SolidMolecular weight:439.42CDK7-IN-13
CAS:<p>CDK7-IN-13: A potent pyrimidine-based CDK7 inhibitor, potential for various cancers. See CN114249712A.</p>Formula:C20H23F3N6OSPurity:99.22%Color and Shape:SolidMolecular weight:452.5Indirubin-3'-monoxime-5-sulphonic acid
CAS:<p>Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of GSK-3β, CDK5, and CDK1 with IC50s of 80nM,5 nM, and 7 nM, respectively.</p>Formula:C16H11N3O5SPurity:98%Color and Shape:SolidMolecular weight:357.3410-Deazaaminopterin
CAS:<p>10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.</p>Formula:C20H21N7O5Color and Shape:SolidMolecular weight:439.42Antibacterial agent 89
CAS:<p>Antibacterial agent 89 blocks bacterial transcription and clostridial cytotoxins, inhibiting β'CH-σ interactions.</p>Formula:C21H10Cl2F3NO5SColor and Shape:SolidMolecular weight:516.27P1788
CAS:<p>P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].</p>Formula:C15H17NO3Color and Shape:SolidMolecular weight:259.3Cdc7-IN-7c
CAS:<p>Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer.</p>Formula:C15H17N5OSPurity:98.19% - 99.22%Color and Shape:SolidMolecular weight:315.39AS-0141
CAS:<p>AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM)，具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶，在细胞周期中对 DNA 复制的启动至关重要。</p>Formula:C21H22F3N5O4Purity:99.97%Color and Shape:SolidMolecular weight:465.43Anticancer agent 73
CAS:<p>Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.</p>Formula:C14H15NO4Purity:99.19%Color and Shape:SolidMolecular weight:261.27AzddMeC
CAS:<p>AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infection</p>Formula:C10H14N6O3Purity:97.14% - 99.62%Color and Shape:SolidMolecular weight:266.26ITX3
CAS:<p>ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.</p>Formula:C22H17N3OSPurity:99.02%Color and Shape:SolidMolecular weight:371.45Firategrast
CAS:<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Formula:C27H27F2NO6Purity:99.16%Color and Shape:SolidMolecular weight:499.5116-9e
CAS:<p>116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.</p>Formula:C31H32N2O5Purity:99.55%Color and Shape:SolidMolecular weight:512.6D-I03
CAS:<p>D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.</p>Formula:C23H36N6SPurity:99.65%Color and Shape:SolidMolecular weight:428.64CF-1743
CAS:<p>CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication.</p>Formula:C22H26N2O5Purity:99.6% - 99.79%Color and Shape:SolidMolecular weight:398.45Abemaciclib metabolite M20
CAS:<p>Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂，可用于癌症治疗的相关研究。</p>Formula:C27H32F2N8OPurity:98.1% - 99.08%Color and Shape:SolidMolecular weight:522.59hDHODH-IN-7
CAS:<p>hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.</p>Formula:C21H23FN4OPurity:99.87%Color and Shape:SolidMolecular weight:366.43DS18561882
CAS:<p>DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.</p>Formula:C28H31F3N4O6SPurity:98.19% - >99.99%Color and Shape:SolidMolecular weight:608.63CD532
CAS:<p>CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.</p>Formula:C26H25F3N8OPurity:99.49%Color and Shape:SolidMolecular weight:522.52GKI-1
CAS:<p>GKI-1, a GWL kinase inhibitor: IC50 - 4.9 µM for hGWLFL, 2.5 µM for hGWL-KinDom, 11 µM for ROCK1; weak on PKA.</p>Formula:C15H12ClN3Purity:99.96%Color and Shape:SolidMolecular weight:269.73Elarofiban
CAS:<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Formula:C22H32N4O4Purity:98.76%Color and Shape:SolidMolecular weight:416.51CDK9-IN-10
CAS:<p>CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.</p>Formula:C22H16O5Purity:99.8%Color and Shape:SolidMolecular weight:360.36Galocitabine
CAS:<p>Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.</p>Formula:C19H22FN3O8Purity:99.89%Color and Shape:SolidMolecular weight:439.39Caracemide
CAS:<p>Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.</p>Formula:C6H11N3O4Purity:99.8%Color and Shape:SolidMolecular weight:189.176RK73
CAS:<p>6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).</p>Formula:C13H17N5O2SPurity:99.91%Color and Shape:SolidMolecular weight:307.37GS-6620 PM
CAS:<p>GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.</p>Formula:C13H15N5O4Purity:98.52% - 98.7%Color and Shape:SolidMolecular weight:305.29CHK1-IN-3
CAS:<p>CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).</p>Formula:C20H23N9OPurity:98.78%Color and Shape:SolidMolecular weight:405.4610-Formylfolic acid
CAS:<p>10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.</p>Formula:C20H19N7O7Purity:98.42%Color and Shape:SolidMolecular weight:469.419-Isopropylolomoucine
CAS:<p>9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.</p>Formula:C17H22N6OPurity:99.82%Color and Shape:SolidMolecular weight:326.4TC-S 7005
CAS:<p>TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).</p>Formula:C21H17N3O3Purity:99.516%Color and Shape:SolidMolecular weight:359.38CRT-0105950
CAS:<p>CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.</p>Formula:C21H16ClN3OSPurity:99.78% - 99.86%Color and Shape:SolidMolecular weight:393.89CDK8-IN-1
CAS:<p>CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).</p>Formula:C11H8F3N3OPurity:98.48%Color and Shape:SolidMolecular weight:255.2AGX51
CAS:<p>AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.</p>Formula:C27H29NO4Purity:97.65%Color and Shape:OilMolecular weight:431.52Peldesine
CAS:<p>Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.</p>Formula:C12H11N5OPurity:99.27% - 99.9%Color and Shape:SolidMolecular weight:241.256-Hydroxy-DOPA
CAS:<p>6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.</p>Formula:C9H11NO5Purity:97.78% - 97.95%Color and Shape:SolidMolecular weight:213.19NR2F6 modulator-1
CAS:<p>NR2F6 modulator-1, a potent agent for NR2F6, affects immune response and tumor stem cell activity.</p>Formula:C23H17NO5SPurity:98.31%Color and Shape:SolidMolecular weight:419.45Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Formula:C27H21N3O3Purity:99.22%Color and Shape:SolidMolecular weight:435.47Cytembena
CAS:<p>Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.</p>Formula:C11H8BrNaO4Purity:99.35%Color and Shape:White PowderMolecular weight:307.07Talviraline
CAS:<p>Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a</p>Formula:C15H20N2O3S2Purity:99.82%Color and Shape:SolidMolecular weight:340.46HA-1004
CAS:<p>HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.</p>Formula:C12H15N5O2SPurity:99.56% - 99.63%Color and Shape:SolidMolecular weight:293.34dCeMM2
CAS:<p>dCeMM2 degrades glue by promoting CDK12-cyclin K ubiquitination and degradation via CRL4B ligase interaction.</p>Formula:C16H11ClN6OSPurity:99.68%Color and Shape:SolidMolecular weight:370.82TTP-8307
CAS:<p>TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.</p>Formula:C27H21FN4OPurity:98.95%Color and Shape:SolidMolecular weight:436.48BioE-1115
CAS:<p>BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).</p>Formula:C19H18FN3O2Purity:97.54%Color and Shape:SolidMolecular weight:339.36CHD1Li 6.11
CAS:<p>CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.</p>Formula:C21H22BrN5OSPurity:99.04%Color and Shape:SolidMolecular weight:472.4(S)-PF-06873600
CAS:<p>(S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK.</p>Formula:C20H27F2N5O4SPurity:98.59%Color and Shape:SolidMolecular weight:471.52Haspin-IN-3
CAS:<p>Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.</p>Formula:C16H10N2O3Purity:98.78%Color and Shape:SolidMolecular weight:278.26Ryuvidine
CAS:<p>Ryuvidine is a dual inhibitor of KDM5A and SETD8, an inducer of the DNA damage response, and can be used to study breast cancer and erythroderma.</p>Formula:C15H12N2O2SPurity:98.6%Color and Shape:SolidMolecular weight:284.33GRK6-IN-1
CAS:<p>GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.</p>Formula:C22H23ClN6O2Purity:99.37%Color and Shape:SolidMolecular weight:438.91UMK57
CAS:<p>UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,</p>Formula:C17H17N3SPurity:99.81%Color and Shape:SolidMolecular weight:295.4Eprociclovir
CAS:<p>Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention of</p>Formula:C11H15N5O3Purity:98.50% - 99.86%Color and Shape:SolidMolecular weight:265.27CDK4/6/1 Inhibitor
CAS:<p>CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM).</p>Formula:C28H30F2N6Purity:99.26% - 99.72%Color and Shape:SolidMolecular weight:488.57hSMG-1 inhibitor 11e
CAS:<p>hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.</p>Formula:C26H27N7O3SPurity:99.89%Color and Shape:SolidMolecular weight:517.6BML-259
CAS:<p>BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.</p>Formula:C14H16N2OSPurity:99.84%Color and Shape:SolidMolecular weight:260.35SB-747651A Dihydrochloride
CAS:<p>SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.</p>Formula:C16H24Cl2N8OPurity:98.05%Color and Shape:SolidMolecular weight:415.32RP-6306
CAS:<p>Lunresertib (RP-6306) is a potent, selective, and orally active PKMYT1 inhibitor with an IC50 of 14 nM.Cost-effective and quality-assured.</p>Formula:C18H20N4O2Purity:98.41% - 99.28%Color and Shape:SolidMolecular weight:324.38SEL120-34A
CAS:<p>SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.</p>Formula:C15H18Br2N4Purity:99.764% - 99.84%Color and Shape:SolidMolecular weight:414.14CDK-IN-2
CAS:<p>CDK-IN-2 (CDK inhibitor II) is a potent and specific CDK9 inhibitor (IC50: <8 nM).</p>Formula:C18H19ClFN3O2Purity:99.67%Color and Shape:SolidMolecular weight:363.81DDRI-18
CAS:<p>DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.</p>Formula:C26H20N6Purity:98%Color and Shape:SolidMolecular weight:416.48ZIM
CAS:<p>ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.</p>Formula:C20H19N3O3Purity:99.85%Color and Shape:SolidMolecular weight:349.38Cdk2 Inhibitor II
CAS:<p>Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.</p>Formula:C14H11BrN4O3SPurity:97.07%Color and Shape:SolidMolecular weight:395.23Talotrexin ammonium
CAS:<p>Talotrexin ammonium, a non-polyglutamic antifolate, inhibits cancer by targeting DHFR.</p>Formula:C27H30N10O6Purity:97.49%Color and Shape:SolidMolecular weight:590.59NSC16168
CAS:<p>NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.</p>Formula:C17H15NO9S3Purity:99.88%Color and Shape:SolidMolecular weight:473.5PS423
CAS:<p>PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.</p>Formula:C25H23F3O9Purity:98.81% - 99.26%Color and Shape:SolidMolecular weight:524.44ERCC1-XPF-IN-2
CAS:<p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>Formula:C15H13Cl2NO3Purity:98.21%Color and Shape:SolidMolecular weight:326.17(S)-Enitociclib
CAS:<p>(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that inhibits the transcription of anti-apoptotic and pro-survival proteins.</p>Formula:C19H18F2N4O2SPurity:98.98%Color and Shape:SolidMolecular weight:404.43SMN-C2
CAS:<p>SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.</p>Formula:C24H27N5O2Purity:99.14%Color and Shape:SolidMolecular weight:417.5Netivudine
CAS:<p>Netivudine, a potent NRTI with anti-varicella activity, treats HIV by inhibiting reverse transcriptase, reducing viral load.</p>Formula:C12H14N2O6Purity:99.78%Color and Shape:SolidMolecular weight:282.25Poloxin-2
CAS:<p>Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.</p>Formula:C16H15NO3Purity:99.67%Color and Shape:SolidMolecular weight:269.3PCSK9-IN-10
CAS:<p>PCSK9-IN-10: potent oral PCSK9 inhibitor (IC50 = 6.4 µM), upregulates LDLR, curbs atherosclerosis, for hyperlipidemia research.</p>Formula:C18H23N5O4Purity:99.06%Color and Shape:SoildMolecular weight:373.41COH34
CAS:<p>COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM.</p>Formula:C18H15NOSPurity:99.57%Color and Shape:SolidMolecular weight:293.38L82
CAS:<p>L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.</p>Formula:C11H8ClN5O4Purity:97.45% - 98.91%Color and Shape:SolidMolecular weight:309.67RP-6685
CAS:<p>RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.</p>Formula:C22H14F7N5OPurity:99.65%Color and Shape:SoildMolecular weight:497.37SB 328437
CAS:<p>SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).</p>Formula:C21H18N2O5Purity:99.54%Color and Shape:SolidMolecular weight:378.38DENV-IN-5
CAS:<p>Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.</p>Formula:C23H25ClF2N4OSPurity:99.06%Color and Shape:SolidMolecular weight:478.99CDK-IN-11
CAS:<p>CDK-IN-11, a heterocyclic compound, promotes cardiomyocyte maturation [1].</p>Formula:C25H21BrN4O2Color and Shape:SolidMolecular weight:489.36WRN inhibitor 3
CAS:<p>WRN Inhibitor 3 (example 110), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Formula:C20H20N2O5SColor and Shape:SolidMolecular weight:400.45WRN inhibitor 4
CAS:<p>WRN Inhibitor 4 (Example 107), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Formula:C16H14N2O5SColor and Shape:SolidMolecular weight:346.36QR-6401
CAS:<p>QR-6401, a selective macrocyclic CDK2 inhibitor, is orally active with IC50 values of 0.37 nM for CDK2/E1, 10 nM for CDK9/T1, 22 nM for CDK1/A2, 34 nM for CDK6/</p>Formula:C19H23N5O3Purity:98%Color and Shape:SolidMolecular weight:369.42CDK9-IN-8
CAS:<p>CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).</p>Formula:C31H32FN7O3Purity:99.54%Color and Shape:SolidMolecular weight:569.63G4/HDAC-IN-1
<p>G4/HDAC-IN-1, a G4/HDAC dual inhibitor, IC50 1.1 µM, blocks TNBC growth, useful in cancer research.</p>Formula:C36H49ClFN7O4Color and Shape:SolidMolecular weight:698.27CDK9-IN-29
CAS:<p>CDK9-IN-29 (compound Z11) is a potent inhibitor of CDK9, exhibiting high kinase selectivity and an IC50 value of 3.20 nM.</p>Formula:C29H33F2N5O4Purity:98%Color and Shape:SolidMolecular weight:553.6CDK/HDAC-IN-3
CAS:<p>CDK/HDAC-IN-3 is an orally active dual inhibitor of HDACs and CDKs, offering potent and selective inhibition of CDK9, CDK12, CDK13, HDAC1, HDAC2, and HDAC3,</p>Formula:C24H18Cl2N6O3Purity:98%Color and Shape:SolidMolecular weight:509.34c-Myc inhibitor 8
CAS:<p>c-Myc inhibitor 8 suppresses cell growth in various cancers and is used in research.</p>Formula:C19H12BrClF3NO3S2Color and Shape:SolidMolecular weight:538.79Sapacitabine
CAS:<p>Sapacitabine (CS682) is a nucleoside analog precursor with anticancer activity used in the study of leukemia.</p>Formula:C26H42N4O5Purity:98.82%Color and Shape:SolidMolecular weight:490.64Nε-(1-Carboxyethyl)-L-lysine
CAS:<p>Nε-(1-Carboxyethyl)-L-lysine (CEL) is an advanced glycation end-product (AGE). Exposure to CEL reduces glutamate uptake and S100B secretion in the hippocampus.</p>Formula:C9H18N2O4Color and Shape:SolidMolecular weight:218.25BVDU 5′-Triphosphate
CAS:<p>BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.</p>Formula:C11H16BrN2O14P3Purity:98%Color and Shape:SolidMolecular weight:573.08GGTI 2147
CAS:<p>GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.</p>Formula:C28H30N4O3Purity:98.69%Color and Shape:SolidMolecular weight:470.565'-ODMT cEt m5U Phosphoramidite (Amidite)
CAS:<p>5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, demonstrates exceptional safety and antisense activity [1] [2].</p>Formula:C42H51N4O9PColor and Shape:SolidMolecular weight:786.859-Deazaguanine
CAS:<p>9-Deazaguanine is a nucleoside analogue exhibiting inhibitory activity against bovine purine nucleoside phosphorylase (PNP).</p>Formula:C6H6N4OPurity:98%Color and Shape:SolidMolecular weight:150.148-Azahypoxanthine
CAS:<p>8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.</p>Formula:C4H3N5OPurity:99.66%Color and Shape:Light Yellow To Light Beige Fine CrystallineMolecular weight:137.1ATN-161
CAS:<p>ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.</p>Formula:C23H35N9O8SPurity:98%Color and Shape:SolidMolecular weight:597.64Raluridine
CAS:<p>Raluridine is an HIV treatment inhibiting RNA-directed DNA polymerase with IC50 of 1.8 microM, compared to FLT, AZT, ddI, and ddC.</p>Formula:C9H10ClFN2O4Purity:98%Color and Shape:SolidMolecular weight:264.64(2S,3R)-Voruciclib
CAS:<p>(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.</p>Formula:C22H19ClF3NO5Purity:98%Color and Shape:SolidMolecular weight:469.84TC-I 15
CAS:<p>α2β1 integrin inhibitor</p>Formula:C23H28N4O6S2Purity:98%Color and Shape:SolidMolecular weight:520.62αvβ1 integrin-IN-2
CAS:<p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>Formula:C29H38N4O4Purity:98%Color and Shape:SolidMolecular weight:506.64α7β1 integrin modulator-1
CAS:<p>α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].</p>Formula:C23H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:475.56DAM-IN-1
CAS:<p>DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.</p>Formula:C16H17NO4Purity:98%Color and Shape:SolidMolecular weight:287.31CT1113
CAS:<p>CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDX</p>Formula:C25H29N5O2SColor and Shape:SolidMolecular weight:463.6Votoplam
CAS:<p>Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].</p>Formula:C21H25N9OPurity:98%Color and Shape:SolidMolecular weight:419.48NITD008
CAS:<p>NITD008 (7-Deaza-2'-C-acetylene-adenosine) is an adenosine nucleoside inhibitor with antiviral activity that inhibits dengue and Zika viruses.</p>Formula:C13H14N4O4Purity:98.04%Color and Shape:SolidMolecular weight:290.27Aurora Kinases-IN-4
CAS:<p>Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM.</p>Formula:C26H28N8OPurity:98%Color and Shape:SolidMolecular weight:468.55G-5758
CAS:<p>G-5758 is an orally active IRE1α inhibitor with an IC50 of 38 nM for XBP1s. It is used in studies involving multiple myeloma models [KMS-11], demonstrating good tolerance in rats at oral doses up to 500 mg/kg. G-5758 exhibits pharmacodynamic effects comparable to those induced by IRE1 knockdown.</p>Formula:C27H24F4N6O3SColor and Shape:SolidMolecular weight:588.58ON 108600
CAS:<p>ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.</p>Formula:C22H14Cl2N2O6S2Purity:98%Color and Shape:SolidMolecular weight:537.392'-Deoxypseudoisocytidine
CAS:<p>2'-Deoxypseudoisocytidine is a nucleoside analogue.</p>Formula:C9H13N3O4Purity:98%Color and Shape:SolidMolecular weight:227.22ROCK2-IN-7
CAS:<p>ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis.</p>Formula:C26H28FN5OPurity:98%Color and Shape:SolidMolecular weight:445.53PD-1/PD-L1-IN-34
CAS:<p>PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) effectively inhibits the PD-1/PD-L1 interaction (IC 50 = 0.029 μM) and demonstrates selective binding affinity to PD-L1</p>Formula:C35H33ClN2O3Purity:98%Color and Shape:SolidMolecular weight:565.1SZ-015268
CAS:<p>SZ-015268: CDK7 inhibitor, IC50=23.56 nM; hinders HCC70, OVCAR-3, HCT116, HCC1806 cell growth; strong anti-tumor effect.</p>Formula:C25H38N8O3Color and Shape:SolidMolecular weight:498.62ASC-69
CAS:<p>ASC-69 (APY69) is a promising potent inhibitor of the PD-1/PD-L1 signaling pathway, classified as a small-molecule compound [1].</p>Formula:C19H19N7Purity:98%Color and Shape:SolidMolecular weight:345.4ML-099
CAS:<p>ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.</p>Formula:C14H13NO2SPurity:99.73%Color and Shape:SolidMolecular weight:259.32Alatrofloxacin
CAS:<p>Alatrofloxacin is a prodrug of trovafloxacin.</p>Formula:C26H25F3N6O5Color and Shape:SolidMolecular weight:558.51L-739758
CAS:<p>L-739758 is a glycoprotein IIb/IIIa inhibitor.</p>Formula:C22H26N4O5S3Color and Shape:SolidMolecular weight:522.66CCT-271850
CAS:<p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>Formula:C24H29N7OPurity:98%Color and Shape:SolidMolecular weight:431.53Palbociclib orotate
CAS:<p>Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively.</p>Formula:C29H33N9O6Purity:98%Color and Shape:SolidMolecular weight:603.63Lerociclib
CAS:<p>Lerociclib (G1T38) is a CDK4/6 inhibitor with anticancer and antitumor activities, inhibiting CDK4/CyclinD1 and CDK6/CyclinD3.</p>Formula:C26H34N8OPurity:99%Color and Shape:SolidMolecular weight:474.6UNC2170 maleate
CAS:<p>53BP1-binding protein 1 (53BP1) engages with dimethylated lysine 20 on histone 4 (H4K20me2) through its tandem tudor domains within a homodimer configuration, crucial for the DNA damage response. UNC2170, a micromolar 53BP1 ligand, selectively interacts with this site, demonstrating at least 17-fold preference for 53BP1 over similar proteins. This interaction occurs in a pocket formed by the 53BP1's tudor domains. Moreover, UNC2170 acts as an antagonist to 53BP1 in cellular lysates, effectively inhibiting class switch recombination, a process dependent on the functional 53BP1 tudor domain, thus confirming its cellular activity.</p>Formula:C14H21BrN2OC4H4O4Color and Shape:SolidMolecular weight:429.31CDK9-IN-23
CAS:<p>CDK9-IN-23 (Example 4) is a potent inhibitor of CDK9, exhibiting an IC50 value of less than 20 nM [1].</p>Formula:C22H25ClN4O3Purity:98%Color and Shape:SolidMolecular weight:428.91Aurora kinase inhibitor-8
CAS:<p>Aurora kinase inhibitor-8 is a highly selective inhibitor of Aurora kinase.</p>Formula:C30H29N7O3Color and Shape:SolidMolecular weight:535.6DUB-IN-7
CAS:<p>DUB-IN-7 (compound 43), a deubiquitinating enzyme (DUB) inhibitor, has utility in researching diseases driven by aberrant JAK2 activity, including leukemia [1].</p>Formula:C17H19N5OColor and Shape:SolidMolecular weight:309.37m-Se3
CAS:<p>m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].</p>Formula:C29H23IN2SePurity:98%Color and Shape:SolidMolecular weight:605.373-Hydroxyxanthone
CAS:<p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>Formula:C13H8O3Purity:98%Color and Shape:SolidMolecular weight:212.2WRN inhibitor 2
CAS:<p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>Formula:C15H11F3N2O5S2Purity:98%Color and Shape:SolidMolecular weight:420.38Voruciclib hydrochloride
CAS:<p>Voruciclib hydrochloride is an orally active and selective inhibitor of CDK (Ki: 0.626 nM-9.1 nM).</p>Formula:C22H20Cl2F3NO5Purity:98%Color and Shape:SolidMolecular weight:506.3ROCK-IN-9
CAS:<p>ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM.</p>Formula:C20H20FN5O2Purity:98%Color and Shape:SolidMolecular weight:381.4Gly-Arg-Gly-Asp-Ser TFA
CAS:<p>Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.</p>Formula:C19H31F3N8O11Color and Shape:SolidMolecular weight:604.49CDK4/6-IN-17
CAS:<p>CDK4/6-IN-17 (compound 12) is an orally bioavailable inhibitor of CDK4/6, demonstrating potent activity with IC50 values between 10-100 nM in BE(2) cells.</p>Formula:C27H28F4N8Purity:98%Color and Shape:SolidMolecular weight:540.56CCG-232964
CAS:<p>CCG-232964 is an orally active Rho/MRTF/SRF inhibitor that suppresses LPA-induced CTGF gene expression [1].</p>Formula:C15H15ClN2O3SPurity:98%Color and Shape:SolidMolecular weight:338.81NU6300
CAS:<p>NU6300 is a covalent CDK2 inhibitor exhibiting irreversible and ATP-competitive properties and also functions as a GSDMD (Gasdermin D) inhibitor.</p>Formula:C20H23N5O3SPurity:96.08%Color and Shape:SolidMolecular weight:413.49
