Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2235 products of "Chromatin/Epigenetics"
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GSK1324726A
CAS:<p>GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).</p>Formula:C25H23ClN2O3Purity:98.34% - 99.85%Color and Shape:SolidMolecular weight:434.91MT-DADMe-ImmA
CAS:<p>MT-DADMe-ImmA (MTDIA) is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).</p>Formula:C13H19N5OSPurity:99.56%Color and Shape:SolidMolecular weight:293.39Fucosterol
CAS:<p>Fucosterol, from E. stolonifera, has anti-diabetic, anti-adipogenic, anti-cancer properties; it affects PPARα and C/EBPα to control fat cell formation.</p>Formula:C29H48OPurity:98.39% - 99.68%Color and Shape:White PowderMolecular weight:412.69CYC-116
CAS:<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Formula:C18H20N6OSPurity:97.36% - 97.59%Color and Shape:SolidMolecular weight:368.46HIF-2α-IN-4
CAS:<p>HIF-2a translation inhibitor is a compound used as a molecular building block.</p>Formula:C9H9N3O4S2Purity:≥98%Color and Shape:SolidMolecular weight:287.32Niraparib
CAS:<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Formula:C19H20N4OPurity:98% - 99.91%Color and Shape:SolidMolecular weight:320.39Glucosamine sulfate
CAS:<p>Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.</p>Formula:C6H13NO5·H2SO4Purity:99.64%Color and Shape:White CrystalMolecular weight:277.253,6-Dihydroxyflavone
CAS:<p>3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.</p>Formula:C15H10O4Purity:99.92%Color and Shape:SolidMolecular weight:254.24ML324
CAS:<p>ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).</p>Formula:C21H23N3O2Purity:98.22% - 98.57%Color and Shape:SolidMolecular weight:349.43SP-146
<p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>Formula:C25H20FN7OPurity:97.82%Color and Shape:SolidMolecular weight:453.47PFI-2 hydrochloride
CAS:<p>PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),</p>Formula:C23H26ClF4N3O3SPurity:99.31% - 99.91%Color and Shape:SolidMolecular weight:535.98BMS-P5 free base
CAS:<p>BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.</p>Formula:C27H32N6O2Purity:99.88%Color and Shape:SolidMolecular weight:472.584'-Methoxychalcone
CAS:<p>4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.</p>Formula:C16H14O2Purity:99.86%Color and Shape:SolidMolecular weight:238.28Niraparib tosylate monohyrate
CAS:<p>Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.</p>Formula:C26H30N4O5SPurity:97.7% - 98.41%Color and Shape:SolidMolecular weight:510.61BAY 87-2243
CAS:<p>BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).</p>Formula:C26H26F3N7O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:525.53BRD4770
CAS:<p>BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.</p>Formula:C25H23N3O3Purity:99.82%Color and Shape:SolidMolecular weight:413.47HNHA
CAS:<p>HNHA is an inhibitor of HDAC.</p>Formula:C17H21NO2SPurity:98.04%Color and Shape:SolidMolecular weight:303.42Daminozide
CAS:<p>Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.</p>Formula:C6H12N2O3Purity:99.86%Color and Shape:White Crystalline Solid Physical Description Odorless White Crystals Or Powder (Ntp 1992)Molecular weight:160.17MI-463
CAS:<p>MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).</p>Formula:C24H23F3N6SPurity:99.18% - >99.99%Color and Shape:SolidMolecular weight:484.541,2-Dipalmitoyl-sn-glycerol
CAS:<p>1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.</p>Formula:C35H68O5Purity:97.84% - 99.78%Color and Shape:SolidMolecular weight:568.91KC7F2
CAS:<p>KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.</p>Formula:C16H16Cl4N2O4S4Purity:98% - 99.11%Color and Shape:SolidMolecular weight:570.38IOX2
CAS:<p>IOX2 is a selective HIF PHD inhibitor, active in cells with 21 nM IC50 for PHD2/ELGN-1, not inhibiting FIH at 20uM.</p>Formula:C19H16N2O5Purity:98% - 99.59%Color and Shape:SolidMolecular weight:352.34GLPG0634 analog
CAS:<p>GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.</p>Formula:C23H18N6O2Purity:99.52% - >99.99%Color and Shape:SolidMolecular weight:410.43TIQ-A
CAS:<p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>Formula:C11H7NOSPurity:99.75%Color and Shape:SolidMolecular weight:201.24N-Oxalylglycine
CAS:<p>N-Oxalylglycine (Oxalylglycine) is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes.</p>Formula:C4H5NO5Purity:99.23%Color and Shape:Colourless SolidMolecular weight:147.09GSK-J4 Hydrochloride
CAS:<p>GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.</p>Formula:C24H28ClN5O2Purity:97.95% - 98.23%Color and Shape:SolidMolecular weight:453.97OTS186935 hydrochloride
<p>OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.</p>Formula:C25H27Cl2N5O2Color and Shape:SolidMolecular weight:522.31SGC707
CAS:<p>SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.</p>Formula:C16H18N4O2Purity:98.45% - 99.79%Color and Shape:SolidMolecular weight:298.34FG-2216
CAS:<p>FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.</p>Formula:C12H9ClN2O4Purity:97.1% - >99.99%Color and Shape:SolidMolecular weight:280.66Momelotinib
CAS:<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Formula:C23H22N6O2Purity:97.47% - 99.56%Color and Shape:SolidMolecular weight:414.46C-82
CAS:<p>C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.</p>Formula:C33H34N6O4Purity:98.86% - 99.66%Color and Shape:SolidMolecular weight:578.66DMOG
CAS:<p>DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.</p>Formula:C6H9NO5Purity:80.23% - 99.98%Color and Shape:SolidMolecular weight:175.14TG101209
CAS:<p>TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.</p>Formula:C26H35N7O2SPurity:99% - >99.99%Color and Shape:SolidMolecular weight:509.67SC99
CAS:<p>SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.</p>Formula:C15H8Cl2FN3OPurity:99.56%Color and Shape:SolidMolecular weight:336.15BMS-P5
CAS:<p>BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.</p>Formula:C27H33ClN6O2Purity:99.88%Color and Shape:SolidMolecular weight:509.04Birabresib
CAS:<p>Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4</p>Formula:C25H22ClN5O2SPurity:98.3% - 99.36%Color and Shape:SolidMolecular weight:491.99C-7280948
CAS:<p>C-7280948 is a PRMT1 inhibitor.</p>Formula:C14H16N2O2SPurity:99.55% - ≥95%Color and Shape:SolidMolecular weight:276.35JW 55
CAS:<p>JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2</p>Formula:C25H26N2O5Purity:99.31% - 99.76%Color and Shape:SolidMolecular weight:434.48Rucaparib
CAS:<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Formula:C19H18FN3OPurity:98.24% - 99.80%Color and Shape:SolidMolecular weight:323.36WDR5-0103
CAS:<p>WDR5-0103 (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).</p>Formula:C21H25N3O4Purity:98% - 99.61%Color and Shape:SolidMolecular weight:383.44Benzamide
CAS:<p>Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.</p>Formula:C7H7NOPurity:99.66%Color and Shape:Colorless Crystals Physical Description White Powder (Ntp 1992)Molecular weight:121.14MR837
CAS:<p>MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.</p>Formula:C16H14N2OSPurity:99.77% - 99.85%Color and Shape:SolidMolecular weight:282.36AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48GSK591
CAS:<p>GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).</p>Formula:C22H28N4O2Purity:99.35% - 99.45%Color and Shape:SolidMolecular weight:380.48Niraparib hydrochloride
CAS:<p>Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.</p>Formula:C19H21ClN4OPurity:99.26%Color and Shape:SolidMolecular weight:356.85KG-501
CAS:<p>KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).</p>Formula:C17H13ClNO5PPurity:97.81%Color and Shape:SolidMolecular weight:377.72IDF-11774
CAS:<p>IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).</p>Formula:C23H32N2O2Purity:98.05%Color and Shape:SolidMolecular weight:368.51MK-8617
CAS:<p>MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).</p>Formula:C24H21N5O4Purity:99.38% - >99.99%Color and Shape:SolidMolecular weight:443.45TP0463518
CAS:<p>TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).</p>Formula:C20H18ClN3O6Purity:99.52%Color and Shape:SolidMolecular weight:431.83MI-503
CAS:<p>MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.</p>Formula:C28H27F3N8SPurity:99.87% - 99.99%Color and Shape:SolidMolecular weight:564.63TAK-632
CAS:<p>TAK-632 is a potent pan-Raf inhibitor.</p>Formula:C27H18F4N4O3SPurity:98% - 99.5%Color and Shape:SolidMolecular weight:554.52B2
CAS:<p>B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease</p>Formula:C20H17ClN4O3Purity:99.66%Color and Shape:SolidMolecular weight:396.83NVP-TNKS656
CAS:<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Formula:C27H34N4O5Purity:99.59%Color and Shape:SolidMolecular weight:494.58RO495
CAS:<p>RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays</p>Formula:C17H14Cl2N6OPurity:97.94%Color and Shape:SolidMolecular weight:389.24Tazemetostat hydrobromide
CAS:<p>Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: 392 nM).</p>Formula:C34H45BrN4O4Purity:99.8%Color and Shape:SolidMolecular weight:653.65ME0328
CAS:<p>ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.</p>Formula:C19H19N3O2Purity:99.22%Color and Shape:SolidMolecular weight:321.37Hinokitiol
CAS:<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Formula:C10H12O2Purity:99.49% - 99.67%Color and Shape:SolidMolecular weight:164.2I-CBP112
CAS:<p>I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.</p>Formula:C27H36N2O5Purity:98.18%Color and Shape:SolidMolecular weight:468.59CPI-455
CAS:<p>CPI-455 is a specific KDM5 inhibitor.</p>Formula:C16H14N4OPurity:97.87% - 99.03%Color and Shape:SolidMolecular weight:278.31CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Formula:C26H31BrN8OPurity:98.51% - 99.89%Color and Shape:SolidMolecular weight:551.48BAZ1A-IN-1
CAS:<p>BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.</p>Formula:C16H12N4O3SPurity:99.87%Color and Shape:SolidMolecular weight:340.36KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Formula:C20H20N4OPurity:98.43% - 99.69%Color and Shape:SolidMolecular weight:332.4UNC0642
CAS:<p>UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).</p>Formula:C29H44F2N6O2Purity:98.75% - 99.5%Color and Shape:SolidMolecular weight:546.7GSK6853
CAS:<p>GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.</p>Formula:C22H27N5O3Purity:98.71% - 99.21%Color and Shape:SolidMolecular weight:409.48Nicotinamide Hydrochloride
CAS:<p>Nicotinamide Hydrochloride, a vitamin B3 form, inhibits SIRT2 and melanoma growth, enhancing NAD+, ATP, ROS, and survival in melanoma mice.</p>Formula:C6H7ClN2OColor and Shape:SolidMolecular weight:158.59BMS-911543
CAS:<p>BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.</p>Formula:C23H28N8OPurity:97.69% - 99.98%Color and Shape:SolidMolecular weight:432.52PARP1-IN-5 dihydrochloride
CAS:<p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>Formula:C25H26Cl2N2O5SPurity:98.01%Color and Shape:SolidMolecular weight:537.46dencichine
CAS:<p>Dencichine (ODAP) is a neurotoxic agent and a haemostatic agent, which relates to modulation of the coagulation system, and fibrinolytic system.</p>Formula:C5H8N2O5Purity:99.93% - ≥95%Color and Shape:SolidMolecular weight:176.134-Phenylbutyric acid
CAS:<p>4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.</p>Formula:C10H12O2Purity:98.40% - 99.76%Color and Shape:SolidMolecular weight:164.2Fedratinib hydrochloride hydrate
CAS:<p>Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.</p>Formula:C27H40Cl2N6O4SPurity:98.96% - 99.87%Color and Shape:SolidMolecular weight:615.61PF-06651600 malonate
CAS:<p>PF-06651600 is a potent and selective JAK3 inhibitor.</p>Formula:C18H23N5O5Color and Shape:SolidMolecular weight:389.41Splitomicin
CAS:<p>Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a</p>Formula:C13H10O2Purity:97.09% - 99.11%Color and Shape:SolidMolecular weight:198.22SGC0946
CAS:<p>SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.</p>Formula:C28H40BrN7O4Purity:98% - 99.82%Color and Shape:SolidMolecular weight:618.57Rucaparib tartrate
CAS:<p>Rucaparib tartrate: oral PARP-1/2/3 inhibitor, Ki=1.4 nM; also inhibits H6PD; for studying CRPC.</p>Formula:C23H24FN3O7Color and Shape:SolidMolecular weight:473.457Methyl L-histidinate dihydrochloride
CAS:<p>The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat</p>Formula:C7H13Cl2N3O2Purity:99.74%Color and Shape:White To Off-White PowderMolecular weight:242.1PFI-3
CAS:<p>PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.</p>Formula:C19H19N3O2Purity:99.58% - 99.94%Color and Shape:SolidMolecular weight:321.37PIN1 inhibitor API-1
CAS:<p>API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.</p>Formula:C15H13F3N6O2Purity:98.48%Color and Shape:SolidMolecular weight:366.3FM-381
CAS:<p>FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.</p>Formula:C24H24N6O2Purity:98.44%Color and Shape:SolidMolecular weight:428.49A-196
CAS:<p>A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over</p>Formula:C18H16Cl2N4Purity:99.92%Color and Shape:SolidMolecular weight:359.25UNC 669
CAS:<p>UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.</p>Formula:C15H20BrN3OPurity:97.38%Color and Shape:SolidMolecular weight:338.24Windorphen
CAS:<p>Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.</p>Formula:C17H15ClO3Purity:99.66%Color and Shape:SolidMolecular weight:302.75AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Formula:C17H14N2O3Purity:98.6% - 99.39%Color and Shape:Yellow SolidMolecular weight:294.3DL-α-Hydroxyglutaric acid disodium salt
CAS:<p>DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuran</p>Formula:C5H6Na2O5Purity:≥98%Color and Shape:SolidMolecular weight:192.08Selisistat
CAS:<p>Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).</p>Formula:C13H13ClN2OPurity:98.53% - 99.94%Color and Shape:SolidMolecular weight:248.71WHI-P97 HCl
<p>WHI-P97 HCl is a potent and selective JAK-3 inhibitor.</p>Formula:C16H14Br2ClN3O3Purity:99.49%Color and Shape:SolidMolecular weight:491.56Filgotinib
CAS:<p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>Formula:C21H23N5O3SPurity:98.03% - ≥95%Color and Shape:SolidMolecular weight:425.5OG-L002
CAS:<p>OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.</p>Formula:C15H15NOPurity:97.05% - 98.62%Color and Shape:SolidMolecular weight:225.29Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formula:C29H32N4O3SPurity:98.04% - 99.44%Color and Shape:SolidMolecular weight:516.65DR2313
CAS:<p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>Formula:C8H10N2OSPurity:98.65%Color and Shape:SolidMolecular weight:182.24SAR-20347
CAS:<p>SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).</p>Formula:C21H18ClFN4O4Purity:98.99% - 99.77%Color and Shape:SolidMolecular weight:444.84Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formula:C26H30N6O3Purity:97.88% - 98.79%Color and Shape:White PowderMolecular weight:474.55NCGC00244536
CAS:<p>NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM).</p>Formula:C25H22N2O2Purity:97.2% - 99.72%Color and Shape:SolidMolecular weight:382.45Perindopril
CAS:<p>Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.</p>Formula:C19H32N2O5Color and Shape:White PowderMolecular weight:368.47Amodiaquine
CAS:<p>Amodiaquine is a synthetic aminoquinoline, used to treat malaria.</p>Formula:C20H22ClN3OPurity:99.78% - 99.99%Color and Shape:Crystals From Absolute Ethanol SolidMolecular weight:355.86Lomeguatrib
CAS:<p>Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .</p>Formula:C10H8BrN5OSPurity:99.26% - >99.99%Color and Shape:SolidMolecular weight:326.173-TYP
CAS:<p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>Formula:C7H6N4Purity:99.16% - >99.99%Color and Shape:SolidMolecular weight:146.15MM-102 TFA
CAS:<p>MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.</p>Formula:C37H50F5N7O6Purity:99.4% - 99.78%Color and Shape:SolidMolecular weight:783.83GSK-J1
CAS:<p>GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.</p>Formula:C22H23N5O2Purity:99.23% - 99.67%Color and Shape:SolidMolecular weight:389.45I-BRD9
CAS:<p>I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.</p>Formula:C22H22F3N3O3S2Purity:98.16% - 99.51%Color and Shape:SolidMolecular weight:497.55Eicosapentaenoic Acid sodium
CAS:<p>EPA sodium, an oral omega-3, demethylates DNA, reactivates tumor suppressors, and induces vasodilation.</p>Formula:C20H29NaO2Color and Shape:SolidMolecular weight:324.43PJ34 hydrochloride
CAS:<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Formula:C17H18ClN3O2Purity:98.87% - ≥95%Color and Shape:SolidMolecular weight:331.8G007-LK
CAS:<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Formula:C25H16ClN7O3SPurity:97.63% - 98.17%Color and Shape:SolidMolecular weight:529.96JQKD82
CAS:<p>JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.</p>Formula:C27H40N4O5Purity:100.00%Color and Shape:SolidMolecular weight:500.63Curculigoside
CAS:<p>1.</p>Formula:C22H26O11Purity:99.85%Color and Shape:SolidMolecular weight:466.44Itacitinib
CAS:<p>Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.</p>Formula:C26H23F4N9OPurity:96.4% - 99.5%Color and Shape:SolidMolecular weight:553.51MPT0G211 mesylate
CAS:<p>MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.</p>Formula:C18H19N3O5SColor and Shape:SolidMolecular weight:389.43CPI203
CAS:<p>CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).</p>Formula:C19H18ClN5OSPurity:99.13% - 99.77%Color and Shape:SolidMolecular weight:399.9UPF 1069
CAS:<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Formula:C17H13NO3Purity:98.80% - 99.88%Color and Shape:SolidMolecular weight:279.29ZM-447439
CAS:<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Formula:C29H31N5O4Purity:99.11% - 99.59%Color and Shape:Pale Yellow SolidMolecular weight:513.59Atractylenolide I
CAS:<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Formula:C15H18O2Purity:97.55% - 99.92%Color and Shape:SolidMolecular weight:230.3JNJ-42041935
CAS:<p>JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.</p>Formula:C12H6ClF3N4O3Purity:99.58% - ≥95%Color and Shape:SolidMolecular weight:346.65HJ-PI01
CAS:<p>HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.</p>Formula:C14H11NO2Purity:98.92%Color and Shape:SolidMolecular weight:225.24Pacritinib
CAS:<p>Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).</p>Formula:C28H32N4O3Purity:99.25% - 99.49%Color and Shape:SolidMolecular weight:472.58ABBV-744
CAS:<p>ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.</p>Formula:C28H30FN3O4Purity:97.03% - >99.99%Color and Shape:SolidMolecular weight:491.55Chlorogenic Acid
CAS:<p>Chlorogenic acid is a natural phenol. Chlorogenic acid has anti-inflammatory, antitumor, and antimicrobial effects. Cost-effective and quality-assured.</p>Formula:C16H18O9Purity:98.84% - 99.67%Color and Shape:SolidMolecular weight:354.31GSK484 hydrochloride
CAS:<p>GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.</p>Formula:C27H32ClN5O3Purity:98.32% - 99.62%Color and Shape:SolidMolecular weight:510.03MRTX-1719
CAS:<p>MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.</p>Formula:C23H18ClFN6O2Purity:98.27% - 99.18%Color and Shape:SolidMolecular weight:464.88Bisindolylmaleimide IV
CAS:<p>Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)</p>Formula:C20H13N3O2Purity:98.83%Color and Shape:Dark Red SolidMolecular weight:327.34Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54AZ6102
CAS:<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Formula:C25H28N6OPurity:97.98% - 99.91%Color and Shape:SolidMolecular weight:428.53PKC-iota inhibitor 1
CAS:<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44RBN012759
CAS:<p>RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.</p>Formula:C19H23FN2O3SPurity:98.87% - 99.96%Color and Shape:SolidMolecular weight:378.46Pacritinib hydrochloride
CAS:<p>Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.</p>Formula:C28H32N4O3·xClHColor and Shape:SolidMS436
CAS:<p>MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.</p>Formula:C18H17N5O3SPurity:97.95% - 98.92%Color and Shape:SolidMolecular weight:383.42OAC1
CAS:<p>OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.</p>Formula:C14H11N3OPurity:99.49% - 99.65%Color and Shape:SolidMolecular weight:237.26Fraxinellone
CAS:<p>1.</p>Formula:C14H16O3Purity:99.35% - 99.92%Color and Shape:SolidMolecular weight:232.27TFMB-(R)-2-HG
CAS:<p>TFMB-(R)-2-HG, a carcinogen in AML, hinders SCF ER-Hoxb8 differentiation after estrogen loss.</p>Formula:C13H11F3O4Purity:97.15%Color and Shape:SolidMolecular weight:288.22(Z)-LFM-A13
CAS:<p>(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.</p>Formula:C11H8Br2N2O2Purity:99.88%Color and Shape:SolidMolecular weight:360SGC-SMARCA-BRDVIII
CAS:<p>SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,</p>Formula:C19H25N5O3Purity:99.54% - 99.92%Color and Shape:SolidMolecular weight:371.43Pim1/AKK1-IN-1
CAS:<p>Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.</p>Formula:C20H13N5OPurity:97.03% - 98.69%Color and Shape:SolidMolecular weight:339.35Hispidulin
CAS:<p>Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).</p>Formula:C16H12O6Purity:98.53% - 99.87%Color and Shape:SolidMolecular weight:300.26Iniparib
CAS:<p>Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).</p>Formula:C7H5IN2O3Purity:98.93%Color and Shape:SolidMolecular weight:292.03SMI-16a
CAS:<p>SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (</p>Formula:C13H13NO3SPurity:99.99%Color and Shape:SolidMolecular weight:263.31AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43NI-57
CAS:<p>NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).</p>Formula:C19H17N3O4SPurity:99.88% - >99.99%Color and Shape:SolidMolecular weight:383.42Menin-MLL inhibitor MI-2
CAS:<p>Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.</p>Formula:C18H25N5S2Purity:97.46%Color and Shape:SolidMolecular weight:375.55RVX-297
CAS:<p>RVX-297 selectively inhibits BD2 domains of BET bromodomains, binding preferentially to BET proteins.</p>Formula:C24H29N3O4Purity:99.62%Color and Shape:SolidMolecular weight:423.5RK-287107
CAS:<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Formula:C22H26F2N4O2Purity:99.64%Color and Shape:SolidMolecular weight:416.46BRD4 Inhibitor 30
CAS:<p>4-(2-fluorophenyl)-1,3-thiazol-2-one: has anti-inflammatory, antibacterial, antifungal, and antitumor properties.</p>Formula:C9H6FNOSPurity:99.68%Color and Shape:SolidMolecular weight:195.21EED226
CAS:<p>EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.</p>Formula:C17H15N5O3SPurity:98.14% - 99.33%Color and Shape:SolidMolecular weight:369.4Ro 31-8220 Mesylate
CAS:<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Formula:C25H23N5O2S·CH4O3SPurity:98.79% - 99.02%Color and Shape:SolidMolecular weight:553.65PF-06726304
CAS:<p>PF-06726304: potent EZH2 inhibitor, effective against tumors, Kis at 0.7 nM (wild-type) and 3.0 nM (Y641N mutant).</p>Formula:C22H21Cl2N3O3Purity:98.19% - 99.51%Color and Shape:SolidMolecular weight:446.33AZ505
CAS:<p>AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).</p>Formula:C29H38Cl2N4O4Purity:98.18%Color and Shape:SolidMolecular weight:577.54Reversine
CAS:<p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>Formula:C21H27N7OPurity:98% - 98.42%Color and Shape:SolidMolecular weight:393.49MLN8054
CAS:<p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>Formula:C25H15ClF2N4O2Purity:98.07% - 98.26%Color and Shape:SolidMolecular weight:476.86SETDB1-TTD-IN-1
CAS:<p>SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.</p>Formula:C28H31N5O2Purity:98.26% - 99.96%Color and Shape:SolidMolecular weight:469.58GSK1379725A
CAS:<p>GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).</p>Formula:C23H23FN6O3Purity:99.51%Color and Shape:SolidMolecular weight:450.47Bromosporine
CAS:<p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>Formula:C17H20N6O4SPurity:99.65% - 99.79%Color and Shape:SolidMolecular weight:404.444-amino-1,8-Naphthalimide
CAS:<p>4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM</p>Formula:C12H8N2O2Purity:95.13%Color and Shape:Yellow Solid PowderMolecular weight:212.2ORY1001
CAS:<p>ORY1001: Oral LSD1/KDM1A inhibitor, highly selective, IC50 <20 nM.</p>Formula:C15H22N2·2HClPurity:99.85% - 99.96%Color and Shape:SolidMolecular weight:303.27Ruboxistaurin mesylate
CAS:<p>Ruboxistaurin: PKC beta inhibitor, eases oxidative stress, heart issues & nephropathy in diabetic rats, halts retinal neovascularization.</p>Formula:C29H32N4O6SPurity:98%Color and Shape:SolidMolecular weight:564.65TP-064
CAS:<p>TP-064: Potent, selective PRMT4 inhibitor, IC50 < 10nM for H3 methylation, 100x selectivity, blocks MED12 methylation at 43nM.</p>Formula:C28H34N4O2Purity:97.85%Color and Shape:SolidMolecular weight:458.6LLY-507
CAS:<p>LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.</p>Formula:C36H42N6OPurity:99.58% - 99.93%Color and Shape:SolidMolecular weight:574.76Picolinamide
CAS:<p>Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.</p>Formula:C6H6N2OPurity:99.6%Color and Shape:SolidMolecular weight:122.12UNC1999
CAS:<p>UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).</p>Formula:C33H43N7O2Purity:99.19% - >99.99%Color and Shape:SolidMolecular weight:569.74AT-9283 HCl
CAS:<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Formula:C19H24ClN7O2Color and Shape:SolidMolecular weight:417.89KDM4D-IN-1
CAS:<p>KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).</p>Formula:C11H7N5OPurity:99.51% - >99.99%Color and Shape:SolidMolecular weight:225.21JMJD7-IN-1
CAS:<p>JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.</p>Formula:C16H8Cl2N2O4Purity:99.66%Color and Shape:SolidMolecular weight:363.15Naphthol AS-E
CAS:<p>Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.</p>Formula:C17H12ClNO2Purity:99.33%Color and Shape:Grey Solid PowderMolecular weight:297.748-CHLOROQUINAZOLIN-4(1H)-ONE
CAS:<p>8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)</p>Formula:C8H5ClN2OPurity:98.79%Color and Shape:SolidMolecular weight:180.59ICG001
CAS:<p>ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.</p>Formula:C33H32N4O4Purity:99.06% - 99.95%Color and Shape:SolidMolecular weight:548.63(R)-(-)-JQ1 Enantiomer
CAS:<p>(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)</p>Formula:C23H25ClN4O2SPurity:99.38%Color and Shape:SolidMolecular weight:456.99AZ9482
CAS:<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Formula:C26H22N6O2Purity:99.18% - 99.86%Color and Shape:SolidMolecular weight:450.49JQEZ5
CAS:<p>JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).</p>Formula:C30H38N8O2Purity:98.14% - ≥98%Color and Shape:SolidMolecular weight:542.68Rucaparib hydrochloride
CAS:<p>Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.</p>Formula:C19H19ClFN3OColor and Shape:SolidMolecular weight:359.83XMD8-92
CAS:<p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>Formula:C26H30N6O3Purity:98.21%Color and Shape:SolidMolecular weight:474.55Rucaparib acetate
CAS:<p>Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.</p>Formula:C21H22FN3O3Color and Shape:SolidMolecular weight:383.423IOX1
CAS:<p>IOX1, a broad-spectrum 2OG oxygenase inhibitor, IC50: KDM4A - 0.6uM, KDM3A - 0.1uM.</p>Formula:C10H7NO3Purity:99.67%Color and Shape:SolidMolecular weight:189.17Menin-MLL inhibitor 20
CAS:<p>Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.</p>Formula:C33H40N8O4Purity:97.77%Color and Shape:SolidMolecular weight:612.72γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formula:C40H58O4Purity:mixture - mixtureColor and Shape:White Or White Crystalline Powder OdourlessMolecular weight:602.9Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.17Ruboxistaurin
CAS:<p>Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.</p>Formula:C28H28N4O3Color and Shape:SolidMolecular weight:468.552,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Formula:C16H13Cl2N3O2Purity:98.77%Color and Shape:SolidMolecular weight:350.2EB-47 dihydrochloride
CAS:<p>EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).</p>Formula:C24H29Cl2N9O6Color and Shape:SolidMolecular weight:610.45SC-43
CAS:<p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>Formula:C21H13ClF3N3O2Purity:98.44%Color and Shape:SolidMolecular weight:431.8WM-8014
CAS:<p>WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.</p>Formula:C20H17FN2O3SPurity:99.64%Color and Shape:SolidMolecular weight:384.42MS31 trihydrochloride
<p>MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.</p>Formula:C20H30Cl3N3O2Color and Shape:SolidMolecular weight:450.83Ro 31-8220
CAS:<p>Ro 31-8220: potent PKC inhibitor (IC50: 5-27 nM). Affects MAPKAP-K1b, MSK1, S6K1, GSK3β (IC50: 3-38 nM), not MKK3/4/6/7.</p>Formula:C25H23N5O2SColor and Shape:SolidMolecular weight:457.55Remodelin hydrobromide
CAS:<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Formula:C15H15BrN4SPurity:97.22% - 99.84%Color and Shape:SolidMolecular weight:363.275BAY-598
CAS:<p>BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.</p>Formula:C22H20Cl2F2N6O3Purity:99.18% - 99.78%Color and Shape:SolidMolecular weight:525.346-Bromo-3-methyl-1,4-dihydroquinazolin-2-one
CAS:<p>CHEMBRDG-BB 7118966 is an inhibitor of Bromodomain-containing protein 4 (human).</p>Formula:C9H9BrN2OPurity:99.28%Color and Shape:SolidMolecular weight:241.08Izilendustat hydrochloride
CAS:<p>Izilendustat hydrochloride inhibits prolyl hydroxylase, stabilizing HIF-1α/HIF-2, with potential to treat various HIF-1α diseases.</p>Formula:C22H29Cl2N3O4Color and Shape:SolidMolecular weight:470.39Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18PF-9366
CAS:<p>PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).</p>Formula:C20H19ClN4Purity:97.28% - 99.88%Color and Shape:SolidMolecular weight:350.84Abrocitinib
CAS:<p>Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).</p>Formula:C14H21N5O2SPurity:99.09% - 99.91%Color and Shape:SolidMolecular weight:323.41SNS-314
CAS:<p>SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.</p>Formula:C18H15ClN6OS2Purity:98%Color and Shape:SolidMolecular weight:430.93PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48Peficitinib
CAS:<p>Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.</p>Formula:C18H22N4O2Purity:98.67% - 99.4%Color and Shape:SolidMolecular weight:326.39Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formula:C18H15N5OPurity:97.03%Color and Shape:SolidMolecular weight:317.34653-47
CAS:<p>653-47 enhances the effects of 666-15 on inhibiting CREB and is a mild CREB inhibitor itself (IC50: 26.3μM).</p>Formula:C20H19ClN2O3Color and Shape:SolidMolecular weight:370.83WHI-P97
CAS:<p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>Formula:C16H13Br2N3O3Purity:99.93%Color and Shape:SolidMolecular weight:455.1Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Pyridone 6
CAS:<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Formula:C18H16FN3OPurity:97.1% - 98.74%Color and Shape:SolidMolecular weight:309.34GN44028
CAS:<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Formula:C18H15N3O2Purity:99.52%Color and Shape:SolidMolecular weight:305.33XAV-939
CAS:<p>XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assay).</p>Formula:C14H11F3N2OSPurity:97.47% - 99.67%Color and Shape:SolidMolecular weight:312.311,5-Isoquinolinediol
CAS:<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Formula:C9H7NO2Purity:98.29% - 99.35%Color and Shape:Of White To White PowderMolecular weight:161.16MS7972
CAS:<p>MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM</p>Formula:C14H13NO2Purity:99.78%Color and Shape:SolidMolecular weight:227.26Molibresib
CAS:<p>Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).</p>Formula:C22H22ClN5O2Purity:97.70% - 99.08%Color and Shape:SolidMolecular weight:423.9dCBP-1
CAS:<p>dCBP-1 selectively degrades p300/CBP via CRBN, killing multiple myeloma cells.</p>Formula:C51H63F2N11O10Purity:98.21% - 99.12%Color and Shape:SolidMolecular weight:1028.11GSK 690 Hydrochloride
CAS:<p>GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.</p>Formula:C24H24ClN3OPurity:98%Color and Shape:SolidMolecular weight:405.92
