DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(421 products)
- DNA gyrase(11 products)
- DNA-PK(51 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
Show 3 more subcategories
Found 957 products of "DNA Damage/DNA Repair"
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Palifosfamide tromethamine
CAS:<p>Palifosfamide, a less toxic ifosfamide metabolite, is a DNA-alkylating anticancer agent.</p>Formula:C8H22Cl2N3O5PColor and Shape:SolidMolecular weight:342.16Azemiglitazone
CAS:<p>Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.</p>Formula:C19H17NO5SPurity:98.29% - 99.6%Color and Shape:SolidMolecular weight:371.41UBCS039
CAS:<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Formula:C16H13N3Purity:98.31%Color and Shape:SolidMolecular weight:247.29SW-100
CAS:<p>SW-100 is a potent HDAC6 inhibitor with 2.3 nM IC50, highly selective (>1000-fold), can cross blood-brain-barrier.</p>Formula:C17H17ClN2O2Purity:98.34% - 98.47%Color and Shape:SolidMolecular weight:316.78GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Formula:C22H24N6OSPurity:98.56% - 99.49%Color and Shape:SolidMolecular weight:420.53L-778123 hydrochloride
CAS:<p>The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.</p>Formula:C22H21Cl2N5OPurity:93.93% - 98.51%Color and Shape:SolidMolecular weight:442.34Indotecan
CAS:<p>Indotecan (LMP-400) is an effective inhibitor of topoisomerase 1(Top1) (IC50: 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively).</p>Formula:C26H26N2O7Purity:97% - 98%Color and Shape:SolidMolecular weight:478.49Hinokitiol
CAS:<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Formula:C10H12O2Purity:99.49% - 99.67%Color and Shape:SolidMolecular weight:164.2PI-3065
CAS:<p>PI-3065 is a novel potent and selective PI3K p110δ inhibitor.</p>Formula:C27H31FN6OSPurity:99.84% - ≥95%Color and Shape:SolidMolecular weight:506.64Senaparib
CAS:<p>Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.</p>Formula:C24H20F2N6O3Purity:99.8%Color and Shape:SolidMolecular weight:478.45Rubitecan
CAS:<p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>Formula:C20H15N3O6Purity:97.54%Color and Shape:Yellow Amorphous PowderMolecular weight:393.35Prulifloxacin
CAS:<p>Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone that inhibits bacterial DNA synthesis by blocking topoisomerase II and IV.</p>Formula:C21H20FN3O6SPurity:99.47%Color and Shape:Yellow Or Slightly Yellow PowerMolecular weight:461.46Ceralasertib
CAS:<p>Ceralasertib (AZD6738) is an ATR kinase inhibitor (IC50=1 nM) with selective and oral activity. Ceralasertib has antitumor activity. Cost effective and quality assured.</p>Formula:C20H24N6O2SPurity:98% - 99.99%Color and Shape:SolidMolecular weight:412.51VE-821
CAS:<p>VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).</p>Formula:C18H16N4O3SPurity:97.19% - 99.97%Color and Shape:SolidMolecular weight:368.41Cycloastragenol
CAS:<p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>Formula:C30H50O5Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:490.71γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formula:C40H58O4Purity:mixture - mixtureColor and Shape:White Or White Crystalline Powder OdourlessMolecular weight:602.9Thiomyristoyl
CAS:<p>Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.</p>Formula:C34H51N3O3SPurity:99.16%Color and Shape:SolidMolecular weight:581.85MN-64
CAS:<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Formula:C18H16O2Purity:99.5% - 99.93%Color and Shape:SolidMolecular weight:264.32Pixantrone
CAS:<p>Pixantrone has anti-tumor activity that is a DNA intercalator and topoisomerase II inhibitor.</p>Formula:C17H19N5O2Color and Shape:SolidMolecular weight:325.37BMH-21
CAS:<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Formula:C21H20N4O2Purity:99.47% - 99.84%Color and Shape:SolidMolecular weight:360.41
