DNA Damage/DNA Repair
DNA damage/DNA repair inhibitors are compounds that interfere with the processes involved in detecting and repairing DNA damage. These inhibitors are critical for studying the mechanisms of genomic stability, mutagenesis, and the response to DNA damage. They are also important in cancer research, as many tumors rely on specific DNA repair pathways for survival. By inhibiting these pathways, DNA damage/DNA repair inhibitors can enhance the effectiveness of chemotherapy and radiation therapy. At CymitQuimica, we provide a diverse range of high-quality DNA damage/DNA repair inhibitors to support your research in molecular biology, oncology, and pharmacology.
Subcategories of "DNA Damage/DNA Repair"
- ATM/ATR(71 products)
- DNA Alkylation(11 products)
- DNA Methyltransferase(421 products)
- DNA gyrase(11 products)
- DNA-PK(51 products)
- MTH1(1 products)
- Nucleoside Antimetabolite/Analog(1,388 products)
- Reverse Transcriptase(43 products)
- Sirtuin(88 products)
- Telomerase(33 products)
- Topoisomerase(136 products)
Show 3 more subcategories
Found 957 products of "DNA Damage/DNA Repair"
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Lomefloxacin
CAS:<p>Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.</p>Formula:C17H19F2N3O3Purity:98.59%Color and Shape:Off-White To Yellow CrystalsMolecular weight:351.35SIRT-IN-2
CAS:<p>SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).</p>Formula:C15H21N5O3S2Purity:98.26%Color and Shape:SolidMolecular weight:383.49Carboplatin
CAS:<p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>Formula:C6H12N2O4PtPurity:98% - 99.72%Color and Shape:White Crystalline PowderMolecular weight:371.25AES-135
CAS:<p>AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 nM) with anti-tumor activity.</p>Formula:C33H29F6N3O5SPurity:97.72%Color and Shape:SolidMolecular weight:693.66Adenine
CAS:<p>Adenine: a purine nucleobase vital for ATP, NAD, FAD production, and DNA/RNA synthesis.</p>Formula:C5H5N5Purity:99.39% - 99.95%Color and Shape:SolidMolecular weight:135.13Zidovudine
CAS:<p>Zidovudine, a synthetic dideoxynucleoside, blocks DNA replication by inhibiting DNA polymerase after activation.</p>Formula:C10H13N5O4Purity:99.84% - 99.91%Color and Shape:White To Off-White CrystalsMolecular weight:267.24Dithranol
CAS:<p>Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially</p>Formula:C14H10O3Purity:93.49% - 99.33%Color and Shape:Physical Description Lemon Yellow Leaflets Or Plates Or An Orange Powder MeltingMolecular weight:226.23DC-05
CAS:<p>DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).</p>Formula:C25H25N3OPurity:98.95%Color and Shape:SolidMolecular weight:383.49FEN1-IN-1
CAS:<p>FEN1-IN-1 (LNT-1), a FEN1 active site inhibitor, partly works by coordinating Mg2+ ions.</p>Formula:C15H12N2O5SPurity:99.65% - 99.80%Color and Shape:SolidMolecular weight:332.33Nalidixic acid
CAS:<p>Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal range.</p>Formula:C12H12N2O3Purity:99.9% - 99.95%Color and Shape:Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)Molecular weight:232.241-Naphthohydroxamic acid
CAS:<p>1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1</p>Formula:C11H9NO2Purity:99.19%Color and Shape:SolidMolecular weight:187.19GED-0507-34 Levo
CAS:<p>GED-0507-34 Levo,(S)-3-(4-Aminophenyl)-2-methoxypropanoic acid,an orally available PPARγ modulator for amelioration of inflammation-driven intestinal fibrosis.</p>Formula:C10H13NO3Purity:98.19%Color and Shape:SolidMolecular weight:195.22Nalidixic acid sodium salt
CAS:<p>Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.</p>Formula:C12H11N2NaO3Purity:99.72% - 99.95%Color and Shape:White To Off-White PowderMolecular weight:254.22Moxifloxacin hydrochloride
CAS:<p>Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria and atypical pathogens.</p>Formula:C21H25ClFN3O4Purity:99.91% - >99.99%Color and Shape:SolidMolecular weight:437.89Hydroxychloroquine sulfate
CAS:<p>Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.</p>Formula:C18H26ClN3O·H2SO4Purity:98.92% - 99.88%Color and Shape:Odorless SolidMolecular weight:433.95Fleroxacin
CAS:<p>Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.</p>Formula:C17H18F3N3O3Purity:99.58% - 99.79%Color and Shape:White Needle-Like CrystalsMolecular weight:369.34Oxaquin TEA
<p>Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that can be used to study Clostridium difficile infections and</p>Formula:C37H48F2N5O11PPurity:99.79%Color and Shape:SolidMolecular weight:807.77Elimusertib hydrochloride(1876467-74-1 free base)
<p>Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor with anti-tumor</p>Formula:C20H22ClN7OPurity:98.8% - 99.03%Color and Shape:SolidMolecular weight:411.89Ceramides Mixture
CAS:<p>Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.</p>Formula:C36H71NO4Purity:98%Color and Shape:SolidMolecular weight:581.967Abexinostat
CAS:<p>Abexinostat (PCI-24781) is a pan-HDAC inhibitor, strongest on HDAC1; less so on HDACs 2, 3, 6, 10. Very select for HDAC8. In Phase 1/2 trials.</p>Formula:C21H23N3O5Purity:98.19% - 98.43%Color and Shape:SolidMolecular weight:397.42Cetaben
CAS:<p>Cetaben, a non-fibrotic drug, lowers cholesterol and triglycerides without PPARα activation.</p>Formula:C23H39NO2Purity:99.59%Color and Shape:SolidMolecular weight:361.56Sparfloxacin
CAS:<p>Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.</p>Formula:C19H22F2N4O3Purity:99.67% - >99.99%Color and Shape:Light Yellow PowderMolecular weight:392.40Topixantrone 2HCl
CAS:<p>Topixantrone 2HCl is a DNA topoisomerase inhibitor with antitumor activity for the study of gastric and prostate cancer.</p>Formula:C21H28Cl2N6O2Purity:99.96% - >99.99%Color and Shape:SoildMolecular weight:467.39Ofloxacin
CAS:<p>Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic.</p>Formula:C18H20FN3O4Purity:99.33% - 99.87%Color and Shape:Off-White SolidMolecular weight:361.37Tallimustine HCl
CAS:<p>Tallimustine HCl, an AT-specific alkylating agent, treats leukemia in immunodeficiency mouse models.</p>Formula:C32H39Cl3N10O4Purity:98.52%Color and Shape:SoildMolecular weight:734.08Gatifloxacin
CAS:<p>Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.</p>Formula:C19H22FN3O4Purity:99.50% - 99.85%Color and Shape:White PowderMolecular weight:375.39LY518674
CAS:<p>LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.</p>Formula:C23H27N3O4Purity:98.87%Color and Shape:SolidMolecular weight:409.48Levetiracetam
CAS:<p>Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset</p>Formula:C8H14N2O2Purity:99.67% - 99.86%Color and Shape:White Crystalline PowderMolecular weight:170.21Acyclovir
CAS:<p>Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2,</p>Formula:C8H11N5O3Purity:99.77% - >99.99%Color and Shape:Crystals From Methanol SolidMolecular weight:225.2LTURM34
CAS:<p>LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM.</p>Formula:C24H18N2O3SPurity:99.34%Color and Shape:SolidMolecular weight:414.48Altretamine
CAS:<p>Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.</p>Formula:C9H18N6Purity:99.54%Color and Shape:Less Crystalline Solid Insoluble In Water (Ntp 1992) Physical Description Colorless Crystalline Solid Insoluble In Water (Ntp 1992)Molecular weight:210.28G150
CAS:<p>G150 suppresses DSDNA-induced interferon; IC50: 10.2 nM. It's a potent, selective H-CGAS inhibitor.</p>Formula:C18H16Cl2N4O2Purity:97.75%Color and Shape:SolidMolecular weight:391.255-Azacytidine
CAS:<p>5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.</p>Formula:C8H12N4O5Purity:99.31% - 99.79%Color and Shape:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:244.2Telomerase-IN-2
CAS:<p>Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).</p>Formula:C34H39N3O9Purity:99.32%Color and Shape:SolidMolecular weight:633.69NSC 31150
CAS:<p>Indomethacin sodium hydrate (Indometacin sodium hydrate) is a COX1/2 inhibitor that induces migraine headaches and may be used in studies of rheumatoid joints.</p>Formula:C10H5Cl2NO2SPurity:98.07%Color and Shape:SolidMolecular weight:274.12MSDC-0602K
CAS:<p>MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.</p>Formula:C19H16KNO5SPurity:99.42%Color and Shape:SolidMolecular weight:409.5Candesartan
CAS:<p>Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.</p>Formula:C24H20N6O3Purity:98.3% - 99.55%Color and Shape:Colorless Solid CrystallineMolecular weight:440.47Ciprofloxacin
CAS:<p>Ciprofloxacin (Bay-09867) mainly targets bacterial DNA Gyrase (IC50=0.22-0.31 µM) and topoisomerase IV (IC50=0.3-1.9 µM). antibiotic. High-Quality, Low-Cost!</p>Formula:C17H18FN3O3Purity:98.77% - 99.91%Color and Shape:White PowderMolecular weight:331.34STL127705
CAS:<p>STL127705 inhibits Ku 70/80 protein & DNA-PKCS kinase, IC50s: 3.5 μM & 2.5 μM.</p>Formula:C22H20FN5O4Purity:99.53% - 99.81%Color and Shape:SolidMolecular weight:437.42BRD 4354
CAS:<p>BRD 4354 is an inhibitor of HDAC5 and HDAC9. For HDAC5 and HDAC9, the IC50s values are 0.85 and 1.88 μM, respectively.</p>Formula:C21H23ClN4OPurity:99.86%Color and Shape:SolidMolecular weight:382.89Balofloxacin
CAS:<p>Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.</p>Formula:C20H24FN3O4Purity:99.62% - 99.98%Color and Shape:Crystalline SolidMolecular weight:389.42Niraparib (R-enantiomer)
CAS:<p>Niraparib R-enantiomer (MK 4827 R-enantiomer) is an inhibitor of PARP1(IC50 of 2.4 nM).</p>Formula:C19H20N4OPurity:99.83%Color and Shape:SolidMolecular weight:320.39Procarbazine hydrochloride
CAS:<p>Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities.</p>Formula:C12H19N3O·HClPurity:96.99% - ≥98%Color and Shape:(Ntp 1992)Molecular weight:257.76Chlorambucil
CAS:<p>Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.</p>Formula:C14H19Cl2NO2Purity:97.37% - 98.45%Color and Shape:Off-White Slightly Granular Powder Melting Point 65-69°CMolecular weight:304.21Clofibric acid
CAS:<p>Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.</p>Formula:C10H11ClO3Purity:99.47% - 99.8%Color and Shape:Pale Yellow SolidMolecular weight:214.65Cisplatin
CAS:<p>Cisplatin (CDDP) is a DNA cross-linking agent.</p>Formula:Cl2H6N2PtPurity:97.13% - 99.63%Color and Shape:Orange-Yellow To Deep Yellow Solid Or PowderMolecular weight:300.04Methotrexate
CAS:<p>Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.</p>Formula:C20H22N8O5Purity:96.84% - 99.91%Color and Shape:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisMolecular weight:454.44Ciprofloxacin monohydrochloride
CAS:<p>Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.</p>Formula:C17H18FN3O3·HClPurity:99.5% - >99.99%Color and Shape:White Or Light Yellow Crystalline PowderMolecular weight:367.80Foscarnet sodium
CAS:<p>Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.</p>Formula:CNa3O5PPurity:98.52%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:191.95Ramatroban
CAS:<p>Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis.</p>Formula:C21H21FN2O4SPurity:98.75% - >99.99%Color and Shape:Crystalline SolidMolecular weight:416.47
