Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(147 products)
- Cell wall(5 products)
- IL Receptor(113 products)
- IκB/IKK(61 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(445 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3035 products of "Immunology and Inflammation"
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ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Color and Shape:SolidMolecular weight:120702.76RDR03785
CAS:<p>The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.</p>Formula:C19H18F3NO4Purity:98.92%Color and Shape:SolidMolecular weight:381.35Schisanchinin D
CAS:<p>Schisanchinin D is a useful organic compound for research related to life sciences. The catalog number is T125682 and the CAS number is 1614245-13-4.</p>Formula:C23H30O6Color and Shape:SolidMolecular weight:402.48712-Oxo phytodienoic acid
CAS:<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Formula:C18H28O3Purity:98%Color and Shape:SolidMolecular weight:292.41Mifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Formula:C61H110F3N6O21PColor and Shape:SolidMolecular weight:1351.52Galectin-8N-IN-2
<p>Galectin-8N-IN-2 (compound 2) is an effective selective inhibitor of Galectin-8N, with a Ki value of 74 μM.</p>Color and Shape:Odour SolidNF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formula:C62H50N4O4SColor and Shape:SolidMolecular weight:947.15CD22 ligand-1
CAS:<p>CD22 ligand-1 is a potent, selective hCD22 binder (K D 0.335 µM) with potential for B-cell disease research.</p>Formula:C33H34N5NaO10Color and Shape:SolidMolecular weight:683.64Galectin-8-IN-2
CAS:<p>Galectin-8-IN-2 (Compound 10) acts as an inhibitor of galectin-8N [1].</p>Formula:C15H20O7Color and Shape:SolidMolecular weight:312.32Interleukin II (60-70)
<p>Interleukin 2 (IL-2) peptide: NH2-LEU-THR-PHE-LYS-PHE-TYR-MET-PRO-LYS-LYS-ALA-COOH, MW 1373.7, immune cytokine.</p>Formula:C68H104N14O14S1Purity:98%Color and Shape:SolidMolecular weight:1373.7Clivatuzumab
CAS:<p>Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good</p>Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:145.42 kDaEritoran
CAS:<p>Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.</p>Formula:C66H126N2O19P2Color and Shape:SolidMolecular weight:1313.66Chitohexaose hexahydrochloride
CAS:<p>Chitohexaose hexahydrochloride, a TLR4-inhibiting chitosan derivative, blocks LPS-induced inflammation.</p>Formula:C36H74Cl6N6O25Color and Shape:SolidMolecular weight:1203.71ABTIM3-hum03
<p>ABTIM3-hum03 is a humanized anti-TIM3 blood-brain barrier shuttling monoclonal antibody.</p>Purity:97.6% (SDS-PAGE); 98.6% (SEC-HPLC) - 97.6% (SDS-PAGE); 98.6% (SEC-HPLC)Color and Shape:Odour LiquidMaritimetin
CAS:<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Formula:C15H10O6Color and Shape:SolidMolecular weight:286.24Ara-F-NAD+
CAS:<p>Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.</p>Formula:C21H26FN7O13P2Color and Shape:SolidMolecular weight:665.421NH2-UAMC1110 TFA
CAS:<p>NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating</p>Formula:C23H24F5N5O5Purity:99.02%Color and Shape:SolidMolecular weight:545.46CP-289
CAS:<p>CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.</p>Formula:C30H35ClN2O2Purity:99.97%Color and Shape:SoildMolecular weight:491.06L 012 sodium salt
CAS:<p>L 012 sodium salt: chemiluminescent probe for oxygen & nitrogen detection; identifies superoxides & Nox inhibitors.</p>Formula:C13H8ClN4NaO2Purity:98.08% - 98.70%Color and Shape:SolidMolecular weight:310.67TMV-IN-6
<p>TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat</p>Formula:C29H27N3OSColor and Shape:SolidMolecular weight:465.613-Methoxycatechol
CAS:<p>3-Methoxycatechol: lignin-based, esophageal carcinogen. 1,2-Dihydroxy-3-methoxybenzene: potent anti-EMCV.</p>Formula:C7H8O3Purity:99.31%Color and Shape:SolidMolecular weight:140.14Topramezone
CAS:<p>Topramezone is a 4-HPPD inhibitor herbicide for post-emergence weed control in corn.</p>Formula:C16H17N3O5SColor and Shape:SolidMolecular weight:363.39Lonazolac Calcium
CAS:<p>Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.</p>Formula:C34H24CaCl2N4O4Purity:98%Color and Shape:SolidMolecular weight:663.56NOD2 agonist 3
<p>NOD2agonist 3 (Compound 5) is an effective NOD2 agonist with an EC50 value of 111.45 nM, demonstrating immunoenhancing properties.</p>Formula:C27H39N3O7Color and Shape:SolidMolecular weight:517.61RIPK1-IN-27
<p>RIPK1-IN-27 (compound 19) is an inhibitor of RIPK1.</p>Formula:C27H28N4O3Color and Shape:SolidMolecular weight:456.544-methyl-6-phenyl-2H-pyranone
CAS:<p>4-methyl-6-phenyl-2H-pyranone from Scutellaria boosts mitochondria, shields astrocytes from peroxide.</p>Formula:C12H10O2Purity:>99.99%Color and Shape:SolidMolecular weight:186.21MC-ND-18
<p>MC-ND-18 is an ATTEC degrader that facilitates the degradation of NLRP3 via autophagy, exhibiting a DC50 of 125.5 nM in THP-1 cells. It is composed of an NLRP3 ligand, a linker, and an LC3 ligand.</p>Formula:C42H42Br2IN3O9SMolecular weight:1049.00532β-Amyrin acetate
CAS:<p>Beta-Amyrin acetate: HMGCR & sEH inhibitor (IC50 3.4 μM), anti-inflammatory, antifungal, antioxidant, anti-hyperlipidemic.</p>Formula:C32H52O2Purity:99.87%Color and Shape:SolidMolecular weight:468.753-O-(2'E,4'Z-Decadienoyl)ingenol
<p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>Formula:C30H42O6Color and Shape:SolidMolecular weight:498.66Anti-inflammatory agent 78
<p>Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. It effectively inhibits PGE2, PGE1, COX-2, and COX-1. Additionally, Anti-inflammatory agent 78 suppresses the release of NO in LPS-stimulated RAW 264.7 cell lines.</p>Formula:C19H14ClNO4Molecular weight:355.06114PROTAC IRAK4 degrader-11
<p>PROTACIRAK4 degrader-11 (compound 15) is a PROTAC molecule utilizing a Cereblon ligand, achieving a maximal IRAK4 degradation rate of 96.25% in HEK293 cells, with a DC50 value of 2.29 nM.</p>Formula:C41H41F3N8O6Molecular weight:798.31012Englumafusp alfa
<p>Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,</p>Color and Shape:Odour LiquidBMS-986235
CAS:<p>BMS-986235 (LAR-1219), an oral FPR2 agonist, EC50: 0.41 nM (hFPR2), 3.4 nM (mFPR2), may prevent heart failure.</p>Formula:C18H17F2N3O3Purity:99.85%Color and Shape:SolidMolecular weight:361.34M133 peptide
<p>The M133 peptide is a coronavirus-specific CD4 T cell epitope. In mice infected with the neurotropic coronavirus (strain JHM of mouse hepatitis virus), the M133 peptide demonstrates immunodominance. It activates CD4 T cells by forming an MHC/peptide complex through binding with MHC II molecules, which is recognized by specific TCRs.</p>Formula:C84H130N20O25Molecular weight:1818.9516dsVACV-70mer sodium
<p>dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.</p>OVA Peptide (323-339)
CAS:<p>OVA Peptide (323-339) is an immunodominant epitope peptide, MHC class II-restricted T-cell epitope , and a B-cell epitope that is recognized by IgE antibodies.</p>Formula:C74H120N26O25Purity:99.38%Color and Shape:SolidMolecular weight:1773.9Biotin-labeled ODN 1826 sodium
<p>Biotin-labeled ODN 1826 (sodium), a class B CpG oligodeoxynucleotide (ODN), serves as a TLR9 agonist and facilitates assessment of CpG ODN cellular uptake and</p>Color and Shape:Odour SolidSuc-Tyr-Val-Ala-Asp-pNA
CAS:<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Formula:C31H38N6O12Color and Shape:SolidMolecular weight:686.675GB1908
<p>GB1908 is a selective oral inhibitor of galectin-1 (galectin-1), with Ki values of 57 nM for human galectin-1 and 72 nM for mouse galectin-1. It demonstrates over 50-fold selectivity for galectin-1 compared to galectin-3. GB1908 can be utilized in lung cancer research.</p>Formula:C18H18Cl2N4O5S2Molecular weight:504.00957DOPAL
CAS:<p>DOPAL, a neurotoxic aldehyde from dopamine metabolism, is linked to Parkinson's and can convert to DOPAC or DOPET.</p>Formula:C8H8O3Color and Shape:SolidMolecular weight:152.15β-Interleukin II (44-56)
<p>β-Interleukin II is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH.</p>Formula:C68H113N19O19Purity:98%Color and Shape:SolidMolecular weight:1500.742-Hydroxybenzylamine
CAS:<p>2-Hydroxybenzylamine captures IsoLGs, prevents early atrial fibrillation recurrence post-ablation.</p>Formula:C7H9NOPurity:95.93%Color and Shape:CoaMolecular weight:123.15Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formula:C16H12O5Color and Shape:SolidMolecular weight:284.267Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Formula:C20H28O6Color and Shape:SolidMolecular weight:364.43StemRegenin 1 Hydrochloride
CAS:<p>StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.</p>Formula:C24H24ClN5OSPurity:99.94%Color and Shape:SolidMolecular weight:466MC1
<p>MC1, an effective NLRP3 inhibitor, exhibits a KD value of 19.3 nM and is devoid of cytotoxicity. This compound enhances cognitive function without causing adverse effects and exhibits no hepatotoxicity. MC1 holds potential for research in Alzheimer's disease.</p>Formula:C23H23N3O6S2Color and Shape:SolidMolecular weight:501.58ODN 2395
CAS:<p>ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5'-tcgtcgttttcggcgc:gcgccg-3' [1].</p>Color and Shape:SolidMolecular weight:7035SARS-CoV-2-IN-39
CAS:<p>SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM.</p>Formula:C14H8ClF4NO3Purity:99.86%Color and Shape:SoildMolecular weight:349.66mPGES-1/5-LOX-IN-1
<p>mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.</p>Formula:C20H22N4O6SMolecular weight:446.12601(±)-Phrymarolin II
CAS:<p>(±)-Phrymarolin II is a promising class of inhibitors that targets the tobacco mosaic virus, representing a novel approach in plant virus suppression.</p>Formula:C23H22O10Color and Shape:SolidMolecular weight:458.419Calcitriol Impurities D
CAS:<p>Calcitriol Impurities D: Vitamin hormone, promotes cell differentiation, has bone activity, inhibits HIV, and aids in treating AIDS/viral infections.</p>Formula:C28H46O3Purity:98%Color and Shape:SolidMolecular weight:430.66UNC9036
<p>UNC9036 is a PROTAC degrader of STING, with a DC50 value of 227 nM. The degradation of STING mediated by UNC9036 is dependent on the proteasomal VHL pathway.</p>Formula:C73H95N17O11SMolecular weight:1417.71177Antibiofilm agent-8
<p>Antibiofilm agent-8 (compound Ru2) boosts antibacterial activity under visible light (400-700 nm, 10 J cm-2). It induces oxidative stress by promoting NADH oxidation and reactive oxygen species (ROS) generation, which disrupts the bacterial cell wall.</p>Formula:C35H23ClF6N7PRuMolecular weight:823.03887CP-447697
CAS:<p>CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.</p>Formula:C29H26ClF2N3O2SPurity:99.90%Color and Shape:SoildMolecular weight:554.05Glutaminase C-IN-2
<p>Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.</p>Formula:C24H23N7O2SPurity:98%Color and Shape:SolidMolecular weight:473.55TLR8 agonist 2
CAS:<p>TLR8 agonist 2 activates human TLR8 (EC50=3nM), less effective on TLR7 (EC50=33.33μM).</p>Formula:C16H22N8Color and Shape:SolidMolecular weight:326.408STING agonist-31
CAS:<p>STING agonist-31, a potent STING agonist, exhibits EC50 values of 0.24 μM and 39.51 μM for human STING (h-STING) and murine STING (m-STING), respectively,</p>Formula:C43H51N15O6Color and Shape:SolidMolecular weight:873.96HSV-60mer sodium
<p>HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).</p>SMRT peptide
CAS:<p>SMRT peptide, one of the corepressor factors interacting with the BCL6 BTB domain, binds to the BTB domain of BCL6 to enhance its transcriptional repression function. Additionally, SMRT peptide is utilized for studying protein-protein interactions.</p>Formula:C82H142N26O24Color and Shape:SolidMolecular weight:1876.16COX-2/NLRP3-IN-1
<p>COX-2/NLRP3-IN-1 (Compound 6k) is an inhibitor that targets COX-2 and NLRP3, exhibiting an IC50 value of 1.53 μM for COX-2. This compound exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway.</p>Formula:C24H19Cl2N5OSMolecular weight:495.06874PROTAC IRAK4 degrader-5
CAS:<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Formula:C41H40F3N11O9Color and Shape:SolidMolecular weight:887.834Ezeprogind
CAS:<p>Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can Trust</p>Formula:C25H44N6Purity:99.28%Color and Shape:SolidMolecular weight:428.66Ginger extract
CAS:<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Color and Shape:SolidCAY10512
CAS:<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Formula:C15H13FOColor and Shape:SolidMolecular weight:228.266Cartap hydrochloride
CAS:<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Formula:C18H33Cl2CuN3O3Color and Shape:Colorless Crystalline Slightly Hygroscopic Solid CoaMolecular weight:473.93(-)-10,11-Dihydroxyfarnesol
CAS:<p>(-)-10,11-Dihydroxyfarnesol, from Cryptomarasmius aucubae, inhibits NO production.</p>Formula:C15H28O3Color and Shape:SolidMolecular weight:256.38Benz-AP
CAS:<p>Benz-AP: potent photosensitizer, creates singlet oxygen, more toxic in low hCES2 cancer cells, generates ROS via TPE to kill tumors.</p>Formula:C20H13NO2Color and Shape:SolidMolecular weight:299.32LC-MI-3
<p>LC-MI-3 is an orally active and potent PROTAC degrader of interleukin-1 receptor-associated kinase 4 (IRAK4), with a DC50 value of 47.3 nM. It effectively inhibits the activation of downstream NF-κB signaling. LC-MI-3 is applicable for research in both acute and chronic inflammatory skin conditions.</p>Formula:C39H36N8O8Molecular weight:744.26561DZ-837
<p>DZ-837 is a PROTAC that targets the BCL6 protein. The composition of DZ-837 includes the BCL6 ligand-2, the E3 ubiquitin ligase ligand Thalidomide-4-OH, and a PROTAC Linker. The configuration notably features a conjugate of the E3 ubiquitin ligase ligand and the Linker, designated as 2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-hydroxyethoxy)ethyl)amino)isoindoline-1,3-dione.</p>Formula:C42H44FN9O7SColor and Shape:SolidMolecular weight:837.92NLRP3-IN-52
<p>NLRP3-IN-52 (compund 1) serves as an inhibitor of NLRP3.</p>Formula:C19H25N5O3Color and Shape:SolidMolecular weight:371.43Ara-F-NAD+ sodium
<p>Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].</p>Formula:C21H25FN7NaO13P2Color and Shape:SolidMolecular weight:687.4HPK1-IN-57
<p>HPK1-IN-57 (Compound 10c) is an inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 of 0.09 nM. It suppresses the activity of HPK1 kinase, inhibits the phosphorylation of downstream adaptor protein SLP76 (IC50 of 33.74 nM), and effectively induces the secretion of the T cell activation marker IL-2 (EC50 of 84.24 nM). HPK1-IN-57 holds promise for research in tumor immunotherapy.</p>Formula:C30H36F2N8O3Color and Shape:SolidMolecular weight:594.655WAY-605471
CAS:<p>WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.</p>Formula:C14H15NO3S2Purity:99.62%Color and Shape:SolidMolecular weight:309.4Bifarcept
CAS:<p>Bifarcept, a recombinant antibody targeting the interferon receptor type I (IFN-RI), enhances the serum half-life of IFN-β by facilitating its binding.</p>Color and Shape:LiquidOVA Peptide(257-264) acetate salt
<p>OVA Peptide(257-264) acetate salt is a Class I (Kb)-restricted epitope of OVA. This octamer peptide is presented by Class I MHC molecule H-2Kb derived from ovalbumin.</p>Formula:C47H78N10O15Molecular weight:1022.56481Chitoheptaose heptahydrochloride
CAS:<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Formula:C42H80ClN7O29Color and Shape:SolidMolecular weight:1182.57OATD-02 hydrochloride
<p>OATD-02 hydrochloride is the hydrochloride salt form of OATD-02. It is an orally effective, competitive, reversible, and non-covalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride serves as a sustained-release inhibitor that efficiently blocks the activity of intracellular arginases, with IC50 values of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1). It effectively eliminates tumor-induced immunosuppression caused by both types of arginases. This compound is utilized in research studies on melanoma.</p>Color and Shape:Odour SolidIsosorbide dinitrate
CAS:<p>Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.</p>Formula:C6H8N2O8Purity:99.87%Color and Shape:Hard Colorless Crystals SolidMolecular weight:236.14Porphyra 334
CAS:<p>Porphyra 334 is a mycosporine-like amino acid.</p>Formula:C14H22N2O8Color and Shape:SolidMolecular weight:346.336PSMA-IN-2
CAS:<p>PSMA-IN-2, an inhibitor of PSMA with a K i value of 1.07 nM, exhibits favorable in vivo NIR imaging (λ EM = 1088 nm, λ ex = 808 nm) and is useful for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice [1].</p>Formula:C54H60N14O18S2Color and Shape:SolidMolecular weight:1257.27Human Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Color and Shape:Odour SolidMitoquinol
CAS:<p>Mitoquinol is a mitochondria-targeted antioxidant used in the study of cardiovascular disease by modulating the mitochondrial antioxidant defense system.</p>Formula:C38H49O7PSPurity:98%Color and Shape:SolidMolecular weight:680.83UNC8900
<p>UNC8900 is a VHL-recruiting STINGPROTAC degrader with a DC50 of 0.924 μM. It is applicable for the study of bacterial and viral infections.</p>Formula:C75H99N17O15SMolecular weight:1509.72273RDR 02308
CAS:<p>RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase [1] .</p>Formula:C19H15N3O3Color and Shape:SolidMolecular weight:333.34TMX-201
CAS:<p>TMX-201: TLR7 ligand-phospholipid with potent immune-boosting effect; for breast cancer & melanoma study.</p>Formula:C57H93N6O12PColor and Shape:SolidMolecular weight:1085.36ADU-S100 disodium salt
CAS:<p>ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).</p>Formula:C20H22N10Na2O10P2S2Purity:98%Color and Shape:SolidMolecular weight:734.51POT-4 acetate
<p>POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.</p>Formula:C74H106N22O20S2Purity:98%Color and Shape:SolidMolecular weight:1687.9Z-VRPR-FMK TFA
<p>Z-VRPR-FMK (TFA), a tetrapeptide, irreversibly inhibits MALT1, protecting against influenza A.</p>Formula:C33H50F4N10O8Color and Shape:SolidMolecular weight:790.81ZM640
<p>ZM640 is an NLRP3 inhibitor that promotes IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. It demonstrates low cytotoxicity.</p>Formula:C28H36F3NO8SMolecular weight:603.21137HNGF6A
CAS:<p>increases glucose stimulated insulin secretion and glucose metabolism</p>Formula:C112H198N34O31S2Purity:98%Color and Shape:SolidMolecular weight:2581.11InsB (9-23)
CAS:<p>InsB (9-23) (InsulinB chain (9-23)) is an insulin B chain peptide capable of binding to the class II major histocompatibility complex (MHC) allele I-Ag7. It holds potential for research into various autoimmune diseases, including type 1 diabetes.</p>Formula:C72H116N20O22SMolecular weight:1645.88Pegaldesleukin
CAS:<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Color and Shape:LiquidPSMA-trillium
CAS:<p>PSMA-trillium is a PSMA-targeting compound comprising a PSMA-targeting molecule (PSMA binding agent), a Macropa chelator, and a pharmacokinetics-modulating group (PK modulator). It acts as the non-radioactive variant of Actinium-225-PSMA-Trillium (BAY 3563254), boasting enhanced PSMA targeting and pharmacokinetic properties. PSMA-trillium can bind with Ac through either the Macropa chelator or the radioactive isotope Actinium-225. Actinium-225-PSMA-Trillium effectively inhibits metastatic castration-resistant prostate cancer (mCRPC).</p>Formula:C106H156IN17O34SMolecular weight:2371.44M-TriDAP TFA
<p>M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a bioactive peptide that functions as an agonist for NOD1/2.</p>Formula:C26H43N5O15·xC2HF3O2hSTING activator-1
<p>hSTING activator-1 (Compound 68) is a STING agonist capable of effectively activating various human STING variants (R232, H232, HAQ), with EC50 values of 56 nM, 89 nM, and 51 nM, respectively. This compound activates the type I interferon pathway by directly binding to the STING protein and stabilizing its conformation, which leads to downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 also demonstrates potential in cancer research by inhibiting fibrosarcoma tumor growth.</p>Color and Shape:Odour SolidRedaporfin
CAS:<p>Redaporfin (F-2BMet, LUZ-11) is a PDT cancer photosensitizer; 83% of mice had tumor regression with 1.5 mg/kg and 74 J/cm² light.</p>Formula:C48H38F8N8O8S4Color and Shape:SolidMolecular weight:1135.11FITC-labeled ODN 1668 sodium
<p>FITC-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist.</p>Color and Shape:Odour SolidNLRP3-IN-73
<p>NLRP3-IN-73 (W16) is an orally bioavailable inhibitor that disrupts the assembly of the NLRP3 inflammasome, exhibiting an IC50 value of 0.18 μM for the NLRP3/IL-1β pathway.</p>Color and Shape:Odour SolidBiotin-labeled ODN TTAGGG sodium
<p>Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS.</p>Color and Shape:Odour SolidCDD-3290
<p>CDD-3290 (Compound 20) is an inhibitor of prostate-specific antigen (PSA) with a Ki value of 216 nM. This compound also exhibits inhibitory effects on α-chymotrypsin and elastase.</p>Color and Shape:Odour Solid
