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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3035 products of "Immunology and Inflammation"

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  • FK-565
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    FK-565

    CAS:
    <p>FK-565 is a ligand of nucleotide-binding oligomerization domain-1 (NOD1) that induces a mouse model of arteritis.</p>
    Formula:C22H38N4O9
    Color and Shape:Solid
    Molecular weight:502.559

    Ref: TM-T204684

  • mPGES1-IN-9
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    mPGES1-IN-9

    CAS:
    <p>mPGES1-IN-9 (compound 1_8) is an mPGES1 inhibitor with an IC50 of 0.5 μM and is utilized in anti-inflammatory research.</p>
    Formula:C25H18N4OS
    Color and Shape:Solid
    Molecular weight:422.502

    Ref: TM-T204717

  • Ambuic acid
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    Ambuic acid

    CAS:
    <p>Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.</p>
    Formula:C19H26O6
    Color and Shape:Solid
    Molecular weight:350.41

    Ref: TM-T71860

  • DPP4-In hydrochloride
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    DPP4-In hydrochloride

    CAS:
    <p>DPP4-In (hydrochloride) is an inhibitor of dipeptidyl peptidase 4 (DPP4) that effectively reduces the expression of DPP4.</p>
    Formula:C14H21ClN4O2
    Color and Shape:Solid
    Molecular weight:312.8

    Ref: TM-T201441

  • STING agonist-21
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    STING agonist-21

    CAS:
    <p>STING agonist-21 (compound 1), possessing an EC 50 of 592.8 nM, functions as a STING agonist. It is applicable in cancer research [1].</p>
    Formula:C17H11F6N5O2
    Color and Shape:Solid
    Molecular weight:431.29

    Ref: TM-T87445

  • NIK-IN-2
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    NIK-IN-2

    CAS:
    <p>NIK-IN-2 (compound 1) is an effective inhibitor of NF-κB inducing kinase (NIK), exhibiting a pIC50 of 7.4. It plays a crucial role in cancer research.</p>
    Formula:C20H22N4O3
    Color and Shape:Solid
    Molecular weight:366.41

    Ref: TM-T201462

  • NLRP3-IN-57
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    NLRP3-IN-57

    <p>NLRP3-IN-57 (compound 5) inhibits the NLRP3 inflammasome, consequently downregulating IL-1β levels in THP-1 macrophages induced by LPS+Nigericin.</p>
    Formula:C44H60O7
    Color and Shape:Solid
    Molecular weight:700.94

    Ref: TM-T201467

  • Indeno[1,2,3-cd]pyrene
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    Indeno[1,2,3-cd]pyrene

    CAS:
    <p>Indeno[1,2,3-cd]pyrene, a polycyclic aromatic hydrocarbon, exhibits moderate cytotoxicity to human alveolar epithelial cells (HPAEpiC). Additionally, it enhances allergic pulmonary inflammation responses through the activation of the aryl hydrocarbon receptor.</p>
    Formula:C22H12
    Color and Shape:Solid
    Molecular weight:276.33

    Ref: TM-T201817

  • STING-IN-15
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    STING-IN-15

    CAS:
    <p>STING-IN-15 (compound 66) is a potent STING inhibitor, effectively suppressing human and mouse STING with IC50 values of 116 nM and 96.3 nM, respectively. In the REX1 D18N mouse model, STING-IN-15 significantly reduces tissue damage and inflammation.</p>
    Formula:C20H14F2N4O3
    Color and Shape:Solid
    Molecular weight:396.35

    Ref: TM-T207666

  • 4-Octylphenol
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    4-Octylphenol

    CAS:
    <p>4-Octylphenol is an endocrine disruptor with gender-specific effects on male germ cells, significantly reducing the mitotic index and the number of spermatogonia. It also causes inflammatory damage in the gills of carp by activating the complement system through the C3a/C3a receptor (C3a/C3aR) axis and C5a/C5a receptor 1 (C5a/C5aR1) axis. Furthermore, 4-Octylphenol induces immune suppression by disrupting the balance between helper T (Th) cells 1/Th2 and regulatory T (Treg)/Th17 cells, and triggers inflammatory damage through the Toll-like receptor 7 (Toll-like Receptor (TLR))/inhibitor κBα/nuclear factor κB (TLR7/IκBα/NF-κB) pathway.</p>
    Formula:C14H22O
    Color and Shape:Solid
    Molecular weight:206.32

    Ref: TM-T201798

  • ROS inducer 9
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    ROS inducer 9

    CAS:
    <p>ROS inducer 9 (compound 4e) is an antibacterial agent with a minimum inhibitory concentration (MIC) of 0.25 μg/mL against Escherichia coli. It eradicates bacteria by inhibiting GSH activity and increasing ROS levels. Additionally, ROS inducer 9 exhibits low toxicity toward red blood cells and RAW 264.7 cells.</p>
    Formula:C26H26BrF4N3O3
    Color and Shape:Solid
    Molecular weight:584.401

    Ref: TM-T206928

  • Darizmetinib
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    Darizmetinib

    CAS:
    <p>Darizmetinib (HRX215) is an MKK4 inhibitor.</p>
    Formula:C21H17F2N5O3S
    Purity:98.03% - 99.57%
    Color and Shape:Solid
    Molecular weight:457.45

    Ref: TM-T72956

  • UBS109
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    UBS109

    CAS:
    <p>UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.</p>
    Formula:C18H17N3O
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:291.35

    Ref: TM-T88314

  • KI696
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    KI696

    CAS:
    <p>KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.</p>
    Formula:C28H30N4O6S
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:550.63

    Ref: TM-T11758L

  • AM103
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    AM103

    CAS:
    <p>AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).</p>
    Formula:C36H38N3NaO4S
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:631.76

    Ref: TM-T10314

  • Zharp1-211
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    Zharp1-211

    CAS:
    <p>Zharp1-211 is a RIPK3 inhibitor，reduces JAK/ stat1-mediated chemokines and MHC class II molecules in IECs, (GVHD) for gastrointestinal inflammation.</p>
    Formula:C24H25N5O4
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:447.49

    Ref: TM-T87664

  • Dazostinag disodium
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    Dazostinag disodium

    CAS:
    <p>Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist.Cost-effective and quality-assured.</p>
    Formula:C21H20F2N8Na2O10P2S2
    Purity:98.84% - 99.96%
    Color and Shape:Solid
    Molecular weight:754.48

    Ref: TM-T72482

  • Antiproliferative agent-22
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    Antiproliferative agent-22

    CAS:
    <p>Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 cells.</p>
    Formula:C17H13N3O3
    Purity:99.20% - 99.27%
    Color and Shape:Solid
    Molecular weight:307.3

    Ref: TM-T85699

  • Evixapodlin
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    Evixapodlin

    CAS:
    <p>Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.</p>
    Formula:C34H36Cl2N8O4
    Purity:99.07%
    Color and Shape:Solid
    Molecular weight:691.61

    Ref: TM-T36487

  • HOIPIN-8 sodium
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    HOIPIN-8 sodium

    CAS:
    <p>HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.</p>
    Formula:C23H15F2N4NaO3
    Purity:97.34%
    Color and Shape:Solid
    Molecular weight:456.38

    Ref: TM-T62826