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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3035 products of "Immunology and Inflammation"

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  • HSV-60mer sodium


    <p>HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).</p>
  • NLRP3-IN-55


    <p>NLRP3-IN-55 (Compound 19) is an effective inhibitor of NLRP3, exhibiting an inhibitory concentration (IC50) of 0.34 μM. It targets the NLRP3 protein directly with a dissociation constant (KD) of 0.45 μM, effectively blocking the assembly and activation of the NLRP3 inflammasome. This action results in anti-inflammatory effects and inhibits cell pyroptosis.</p>
    Formula:C32H30ClFN2O4
    Color and Shape:Solid
    Molecular weight:561.04
  • RIPK1-IN-27


    <p>RIPK1-IN-27 (compound 19) is an inhibitor of RIPK1.</p>
    Formula:C27H28N4O3
    Color and Shape:Solid
    Molecular weight:456.54
  • PSMA-DA1

    CAS:
    <p>PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.</p>
    Formula:C50H76IN9O20
    Color and Shape:Solid
    Molecular weight:1250.105
  • PSMA-ALB-56

    CAS:
    <p>PSMA-ALB-56: radioactive, PSMA-targeted ligand, antitumor, combines glutamic urea, DOTA, albumin, with iodophenyl or tolyl fragments.</p>
    Formula:C66H95N11O18
    Color and Shape:Solid
    Molecular weight:1330.52
  • RS 09 TFA


    <p>RS 09 TFA is a TLR4 agonist and LPS peptide analogue, promotes NF-κB nuclear translocation, induces inflammatory cytokine secretion in RAW264.7 macrophages.</p>
    Formula:C33H50F3N9O11
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:805.8
  • Bectumomab

    CAS:
    <p>Bectumomab (IMMU-LL2) is a humanized IgG2a mAb targeting CD22, used in imaging and staging non-Hodgkin's lymphoma.</p>
    Color and Shape:Liquid
  • ZM640


    <p>ZM640 is an NLRP3 inhibitor that promotes IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. It demonstrates low cytotoxicity.</p>
    Formula:C28H36F3NO8S
    Molecular weight:603.21137
  • 4-hydroperoxy 2-Nonenal

    CAS:
    <p>4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.</p>
    Formula:C9H16O3
    Color and Shape:Solid
    Molecular weight:172.224
  • UNC8900


    <p>UNC8900 is a VHL-recruiting STINGPROTAC degrader with a DC50 of 0.924 μM. It is applicable for the study of bacterial and viral infections.</p>
    Formula:C75H99N17O15S
    Molecular weight:1509.72273
  • CD22 ligand-1

    CAS:
    <p>CD22 ligand-1 is a potent, selective hCD22 binder (K D 0.335 µM) with potential for B-cell disease research.</p>
    Formula:C33H34N5NaO10
    Color and Shape:Solid
    Molecular weight:683.64
  • BMS-986148


    <p>BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.</p>
    Purity:98.1% (SDS-PAGE); 99% (SEC-HPLC) - 98.1% (SDS-PAGE); 99% (SEC-HPLC)
    Color and Shape:Odour Liquid
  • OVA Peptide(257-264) acetate salt


    <p>OVA Peptide(257-264) acetate salt is a Class I (Kb)-restricted epitope of OVA. This octamer peptide is presented by Class I MHC molecule H-2Kb derived from ovalbumin.</p>
    Formula:C47H78N10O15
    Molecular weight:1022.56481
  • cGAS-IN-3


    <p>cGAS-IN-3 (compound 30d-S) is an orally active inhibitor of cyclic GMP-AMP synthase (cGAS) that exhibits excellent plasma exposure and low clearance rate. It demonstrates anti-inflammatory properties, significantly reducing pulmonary inflammation in rats.</p>
    Formula:C21H20Cl2F2N4O2
    Molecular weight:468.09314
  • M-TriDAP TFA


    <p>M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a bioactive peptide that functions as an agonist for NOD1/2.</p>
    Formula:C26H43N5O15·xC2HF3O2
  • 4-Methylamino antipyrine hydrochloride

    CAS:
    <p>4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.</p>
    Formula:C12H16ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:253.73
  • PSMA-D5

    CAS:
    <p>PSMA-D5 exhibits a binding affinity for PSMA with a Ki of 0.21 nM and becomes useful for PSMA tracing following radiolabeling. When marked with [68Ga], PSMA-D5 contains a DOTA chelator, facilitating the convenient labeling with therapeutic radionuclides such as 177Lu and 225Ac. Additionally, [68Ga]-labeled PSMA-D5 demonstrates exceptional pharmacokinetic properties and significant tumor uptake in 22Rv1 tumors. This compound can be employed in the synthesis and research of radiolabeled conjugates (RDC).</p>
    Formula:C57H80N12O24
    Color and Shape:Solid
    Molecular weight:1317.31
  • BCOR(498-514), biotinylated


    <p>BCOR(498-514), biotinylated, is the smallest BCL6 binding domain with a KD of 1.32 µM. It can block BCL6-mediated transcriptional repression and induce cell death in lymphoma cells.</p>
    Formula:C98H155N25O29S
    Molecular weight:2178.11433
  • Axinelline A

    CAS:
    <p>Axinelline A: COX inhibitor, IC50 of 2.22 μM (COX-2) &amp; 8.89 μM (COX-1), anti-inflammatory.</p>
    Formula:C12H15NO6
    Color and Shape:Solid
    Molecular weight:269.25
  • Biotin-labeled Agatolimod sodium


    <p>Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>
    Color and Shape:Odour Solid